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IKK beta (IKBKB) (NM_001556) Human Untagged Clone
CAT＃: SC125322
IKBKB (untagged)-Human inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (IKBKB), transcript variant 1
CNY 5,544.00
Product images
CNY 6,281.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | IKK-beta; IKK2; IKKB; IMD15; IMD15A; IMD15B; NFKBIKB |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_001556 edited
ATGAGCTGGTCACCTTCCCTGACAACGCAGACATGTGGGGCCTGGGAAATGAAAGAGCGC CTTGGGACAGGGGGATTTGGAAATGTCATCCGATGGCACAATCAGGAAACAGGTGAGCAG ATTGCCATCAAGCAGTGCCGGCAGGAGCTCAGCCCCCGGAACCGAGAGCGGTGGTGCCTG GAGATCCAGATCATGAGAAGGCTGACCCACCCCAATGTGGTGGCTGCCCGAGATGTCCCT GAGGGGATGCAGAACTTGGCGCCCAATGACCTGCCCCTGCTGGCCATGGAGTACTGCCAA GGAGGAGATCTCCGGAAGTACCTGAACCAGTTTGAGAACTGCTGTGGTCTGCGGGAAGGT GCCATCCTCACCTTGCTGAGTGACATTGCCTCTGCGCTTAGATACCTTCATGAAAACAGA ATCATCCATCGGGATCTAAAGCCAGAAAACATCGTCCTGCAGCAAGGAGAACAGAGGTTA ATACACAAAATTATTGACCTAGGATATGCCAAGGAGCTGGATCAGGGCAGTCTTTGCACA TCATTCGTGGGGACCCTGCAGTACCTGGCCCCAGAGCTACTGGAGCAGCAGAAGTACACA GTGACCGTCGACTACTGGAGCTTCGGCACCCTGGCCTTTGAGTGCATCACGGGCTTCCGG CCCTTCCTCCCCAACTGGCAGCCCGTGCAGTGGCATTCAAAAGTGCGGCAGAAGAGTGAG GTGGACATTGTTGTTAGCGAAGACTTGAATGGAACGGTGAAGTTTTCAAGCTCTTTACCC TACCCCAATAATCTTAACAGTGTCCTGGCTGAGCGACTGGAGAAGTGGCTGCAACTGATG CTGATGTGGCACCCCCGACAGAGGGGCACGGATCCCACGTATGGGCCCAATGGCTGCTTC AAGGCCCTGGATGACATCTTAAACTTAAAGCTGGTTCATATCTTGAACATGGTCACGGGC ACCATCCACACCTACCCTGTGACAGAGGATGAGAGTCTGCAGAGCTTGAAGGCCAGAATC CAACAGGACACGGGCATCCCAGAGGAGGACCAGGAGCTGCTGCAGGAAGCGGGCCTGGCG TTGATCCCCGATAAGCCTGCCACTCAGTGTATTTCAGACGGCAAGTTAAATGAGGGCCAC ACATTGGACATGGATCTTGTTTTTCTCTTTGACAACAGTAAAATCACCTATGAGACTCAG ATCTCCCCACGGCCCCAACCTGAAAGTGTCAGCTGTATCCTTCAAGAGCCCAAGAGGAAT CTCGCCTTCTTCCAGCTGAGGAAGGTGTGGGGCCAGGTCTGGCACAGCATCCAGACCCTG AAGGAAGATTGCAACCGGCTGCAGCAGGGACAGCGAGCCGCCATGATGAATCTCCTCCGA AACAACAGCTGCCTCTCCAAAATGAAGAATTCCATGGCTTCCATGTCTCAGCAGCTCAAG GCCAAGTTGGATTTCTTCAAAACCAGCATCCAGATTGACCTGGAGAAGTACAGCGAGCAA ACCGAGTTTGGGATCACATCAGATAAACTGCTGCTGGCCTGGAGGGAAATGGAGCAGGCT GTGGAGCTCTGTGGGCGGGAGAACGAAGTGAAACTCCTGGTAGAACGGATGATGGCTCTG CAGACCGACATTGTGGACTTACAGAGGAGCCCCATGGGCCGGAAGCAGGGGGGAACGCTG GACGACCTAGAGGAGCAAGCAAGGGAGCTGTACAGGAGACTAAGGGAAAAACCTCGAGAC CAGCGAACTGAGGGTGACAGTCAGGAAATGGTACGGCTGCTGCTTCAGGCAATTCAGAGC TTCGAGAAGAAAGTGCGAGTGATCTATACGCAGCTCAGTAAAACTGTGGTTTGCAAGCAG AAGGCGCTGGAACTGTTGCCCAAGGTGGAAGAGGTGGTGAGCTTAATGAATGAGGATGAG AAGACTGTTGTCCGGCTGCAGGAGAAGCGGCAGAAGGAGCTCTGGAATCTCCTGAAGATT GCTTGTAGCAAGGTCCGTGGTCCTGTCAGTGGAAGCCCGGATAGCATGAATGCCTCTCGA CTTAGCCAGCCTGGGCAGCTGATGTCTCAGCCCTCCACGGCCTCCAACAGCTTACCTGAG CCAGCCAAGAAGAGTGAAGAACTGGTGGCTGAAGCACATAACCTCTGCACCCTGCTAGAA AATGCCATACAGGACACTGTGAGGGAACAAGACCAGAGTTTCACGGCCCTAGACTGGAGC TGGTTACAGACGGAAGAAGAAGAGCACAGCTGCCTGGAGCAGGCCTCATGA >OriGene 5' read for NM_001556 unedited
GCCGCCCCAGCCCCGCCTTCCCCGCCCCGGGGAGCCCGCCCCCTGCCCCGCGTCCCTGCC GACAGAGTTAGCACGACATCAGTATGAGCTGGTCACCTTCCCTGACAACGCAGACATGTG GGGCCTGGGAAATGAAAGAGCGCCTTGGGACAGGGGGATTTGGAAATGTCATCCGATGGC ACAATCAGGAAACAGGTGAGCAGATTGCCATCAAGCAGTGCCGGCAGGAGCTCAGCCCCC GGAACCGAGAGCGGTGGTGCCTGGAGATCCAGATCATGAGAAGGCTGACCCACCCCAATG TGGTGGCTGCCCGAGATGTCCCTGAGGGGATGCAGAACTTGGCGCCCAATGACCTGCCCC TGCTGGCCATGGAGTACTGCCAAAGAGGAGATCTCCGGAAGTACCTGAACCAGTTTGAGA ACTGCTGTGGTCTGCGGGAAAGGTGCATCCTCACCTTGCTGAGAGACATTGCCTCTGCGC TTANATACCTTCTTGAAAACAAAATCATCCATCGGGATCTAAAGCCCAAAAACATCTTCC TGCAGCAAGGAGAACAAAGGTTAATCCACAAAATTATTGCCCTATGATTTGCCCACGGAG CTGGATTAGGGCAGTCTTTTCACATAATTCTGGGGGACCCTGGATTCCTGGCCCCAAACT TCTGGAGCCAAAAAGTACCACGGACCGTCGCTATTGGACTTCGGCCCCTGTCTTTGATGG ATAAGGGCTTTCGGCCTTTCTTCCCACTGGCAGCCCGGGGTGGTGTTTAAAATCCGGGAA AAAAGAGGGGGCTTGTTTGTCCAAACCTAATTGAACGTA >OriGene 3' read for NM_001556 unedited
NGGCCTAGGGTCTTTATAACGGCCTCCTCATTGGNAAGTTAATACATGTTTCACACACAC AATCAGCAGGAGAAAAGTTTCTATAGCCAAATGACATTGATAAACAGTGTTCTTACACAA AGTTAAGCCTGTTTCTTTATTATAAGACTTTTCAGATACTTTCCCAGTGCATAGTGTGAA TCTCCACAAAGCAAGTGAAACATGAATAGCTCCCTAAACTTACTTGACCACAGAATGCTT CATTCTATCTCCATGGAAACCACTTGTGAAAGTCTCCTACTCCAACTTTCTTCTCCAACA AAACTCACCTGTTTGTGATCATCTGAACTCATTTTGTGCTCTTGCCTTTATATAAAAGAG AAGTTCTGTGAAATGTTGAAGAAGCAGGGTTATGGCACTAGTAATGATCCAGGCACTATA CACATTGTTAACATTTTCCATTATTTTAGTTCAGAAGCCCTAACCATATGTATTCTAACA GTGGATTGTGGAACCCACTATGAGTGTTTGAGACGTGTCGCCNTATACGGGAGCTATTTT GTATATGAATCCATTGATTATCCCTGCTAGTTGCCGTGTGAGACGCCCACTCACCGGGCG AGCGCCCTTGCTCGGGCCGGCCTGGGGACCCGGTCGGGCGCCGGCCGGCAGGTTGCTCGG CCCTTGCCCGTGCTGGGGGCGGGCTTTGTCTCTTCTCTCCCTAGGTTGCGTGTGGGTCGC CCCGCTTGTCGCTGGTGGCGTTTTTCCGTCGGGCGCTTTCGGCGCTTCTTCCTCTNNTAC TGCCGCGTGTGGTCGGCACCCCTGCATCTCCCCNCGTTGGTGCTCCCTTTGATGGACTGG GCGCGGCGCCGCTCCGATCATTTGTTGCCGTCTTTTCCCGCCCTTTGCCGCTTTTCGTCT CCCCCCTCCCCCTTTTTTCCCGCCTTTGTTTTATATAGACGCTTAGCCAGAACAACA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001556 |
| Insert Size | 4500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001556.1, NP_001547.1 |
| RefSeq Size | 3916 bp |
| RefSeq ORF | 2271 bp |
| Locus ID | 3551 |
| UniProt ID | O14920 |
| Protein Families | Druggable Genome, Protein Kinase, Transcription Factors |
| Protein Pathways | Acute myeloid leukemia, Adipocytokine signaling pathway, Apoptosis, B cell receptor signaling pathway, Chemokine signaling pathway, Chronic myeloid leukemia, Cytosolic DNA-sensing pathway, Epithelial cell signaling in Helicobacter pylori infection, Insulin signaling pathway, MAPK signaling pathway, Neurotrophin signaling pathway, NOD-like receptor signaling pathway, Pancreatic cancer, Pathways in cancer, Prostate cancer, RIG-I-like receptor signaling pathway, Small cell lung cancer, T cell receptor signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus |
| Gene Summary | The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene. [provided by RefSeq, Sep 2011] Transcript Variant: This variant (1) encodes the longest isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC219154 | IKBKB (Myc-DDK-tagged)-Human inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (IKBKB), transcript variant 1 |
CNY 5,536.00 |
|
| RC219154L1 | Lenti ORF clone of Human inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (IKBKB), transcript variant 1, Myc-DDK-tagged |
CNY 7,936.00 |
|
| RC219154L2 | Lenti ORF clone of Human inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (IKBKB), transcript variant 1, mGFP tagged |
CNY 7,936.00 |
|
| RC219154L3 | Lenti ORF clone of Human inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (IKBKB), transcript variant 1, Myc-DDK-tagged |
CNY 7,936.00 |
|
| RC219154L4 | Lenti ORF clone of Human inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (IKBKB), transcript variant 1, mGFP tagged |
CNY 7,936.00 |
|
| RG219154 | IKBKB (tGFP-tagged) - Human inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (IKBKB), transcript variant 1 |
CNY 7,136.00 |
|
| SC323399 | IKBKB (untagged)-Kinase deficient mutant (K44M) of Human inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (IKBKB) |
CNY 5,544.00 |
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