FBXO46 (BC021978) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	20D7-FC4; F-box only protein 34-like; F-box protein 46; Fbx46; FBXO34L
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >OriGene sequence for BC021978 edited GGTGAGGACGTGGACCTGCTCTCTGTGGCCGAGATGGTGGCCCTGGTGGAACAGCGGGCA GCCCTGGCCCTGCAGAGCTACCCACGACCGACCACCCCAGCGCCTGTAGTCTTTGTGTCC GCCGAGCAAGGTGGACCGGCCAAGGGGGTGGGATCTGAACGGCGGTCCGGTGGTGGGGAC TGCAGCCGTGTAGCCGAGGCCGTGGCCCACTTTGAAGCGCAGAGGGACAGCCCTCCCACC AAGGGCCTCCGCAAGGAAGAGCGGCCCGGGCCAGGCCCTGGGGAGGTGCGCATCGCCTTC CGCATCTCCAACGGCCGGGAGCCCCGTGCACCAGACAGCGGCCTGCCCAGTGGGGGCGGG GGCAGGCCTGGTTGTGCCTACCCTGGCAGCCCAGGTCCTGGGGCCCGAGCCAAGGACAAG ATCACATGTGACTTATACCAGCTCATCAGCCCCTCGCGGGATGCCCTCCCCAGCAACGTG GAGTTCCTGCTGGCCAGGGCGGATGAGGCCAGTGAGGGTGACAGCCCGGCACCCGCCAGG CCTGAGGACACTCCCCCGGCGCCCCCTCCGCCCCCTGCCCGGGACTGCGGAGCGTCAGGC TTCCACGTGGACGTGGTGGTGACGGGCGTGGTAGATGAGTGCATCTTCTTTGGCAAGGAC GGCACCAAGAACGTGAAGGAGGAGACTGTGTGCCTGACGGTCAGCCCGGAGGAACCGCCG CCTCCGGGCCAGCTCTTCTTTCTCCAGAACCGCGGGCCGGACGGGCCCCCGGAGCCACCC CCGGCCGACTCCCCGGCCACTGCGCCCGGCCCAGACGATGCCGAGGGCACGGCGGACACC TCCCTGTGCCGCTTGTACCGGCACGTGTCGCACGACTTCCTAGAGATCCGCTTCAAGATT CAGCGGCTGCTGGAGCCGCGACAGTACATGCTGCTGCTGCCCGAGCACGTGCTGGTCAAG ATCTTCAGCTTCCTGCCCACGCGCGCGCTGGCCGCCCTCAAGTGCACCTGCCACCACTTC AAGGGCATCATCGAGGCGTTTGGCGTGCGGGCCACAGACTCGCGCTGGAGCCGAGACCCG CTCTACCGCGATGATCCGTGCAAACAGTGCCGCAAGAGATACGAGAAGGGCGACGTGTCG CTCTGCCGCTGGCACCCCAAGCCCTACCACCATGACCTGCCTTACGGACGTTCCTACTGG ATGTGCTGCCGTCGAGCCGACCGCGAGACTCCCGGCTGCCGCCTGGGCCTCCACGATAAC AACTGGGTGCTGCCCTGCAATGGGCCAGGCGGGGGCCGGGCCGGCCGGGAGGAGGGGAGG TCAACCCGCGGGAGGGGAGGGGAGAGCCCACCACGCCCACCCCTCCCCTCTCCTCCCGGG AGCCGAGGGTCCGGACTGGGCCGCCTGCCCATTCCCCTACTCCAGGCAGCATTGATCCCT CACCGGAACTGAGCTGGGGTTCAGCAGGGGTGACCCAGGAAAGCCCTCTGCTTGATCCTG TTGATTTTCTACTCTTCAGAACCAGGGCCGTGGACCCTCTGAGAAGGGTGTTTTTTTTTT TTTTTTATCAGCATCTCACTTTCTTCTCCATTCAGCCCCAACCCCCTCCCTGCCATGCTT TCCACCCCAAGGACCCACCAGCAGGGAGCAGACGGCAGCTAATTTTGGTACCACTTAAGG GTCCCCCCATTCTGGCCCCCATCCTCTCCCTCACCCCAATTCTTTCTCGCTGGAGCTGTT ATTTCCCAAGAAGCCGCATCGCCCAAGGTTGGCACCTCTCCTAACCTGCCACACGACAGC TCTCACCTCTCTAGGAATTGGGGGCTGTCAGGTCACAGGTGGGATCTGGCATTTTTTTAT GACAGTCCATTTCTAGATGGTTTGCCTATTAAAGAAGTGGGGGGGAAATACTGTTTTCTC CTTAACCTCAAGCTACCAGTCTCTCCTCTTCCGCGTAGAGGAAGAGGGGGGCAGACAAAA AAAAAAAAAAAAAAA
Restriction Sites	Please inquire
ACCN	BC021978
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	BC021978.2, AAH21978.1
RefSeq Size	1995 bp
Locus ID	23403
Protein Families	Druggable Genome
Gene Summary	Members of the F-box protein family, such as FBXO46, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]

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