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MOV10 (BC009312) Human Untagged Clone
CAT＃: SC126015
MOV10 (untagged)-Human Mov10, Moloney leukemia virus 10, homolog (mouse), mRNA (cDNA clone MGC:15000 IMAGE:4109453), complete cds
CNY 2,950.00
货期*
现货
规格
| Cited in 2 publications. |
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DKFZp667O1423; FLJ32791; fSAP113; functional spliceosome-associated protein 113; gb110; KIAA1631; Mov10, Moloney leukemia virus 10, homolog; Mov10, Moloney leukemia virus 10, homolog (mouse); OTTHUMP00000013677; OTTHUMP00000013679; OTTHUMP00000013680 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for BC009312 edited
AGGGAAAGCTCAGGGCCGCCAACTTCCAGCTGCAGCGGCGACTTTCAGTTTCATTTCCAC GGACCCTCCTGCCTGGGCCGCAGCCGCCGCCGCGATGCCCAGTAAGTTCAGCTGCCGGCA GCTCCGGGAGGCGGGCCAGTGTTTCGAGAGTTTCCTGGTCGTTCGGGGACTGGACATGGA GACAGATCGCGAGCGGCTGCGGACCATTTATAACCGCGACTTCAAGATCAGCTTTGGGAC CCCCGCCCCTGGCTTCTCCTCCATGCTGTATGGAATGAAGATTGCAAATCTGGCCTACGT CACCAAGACTCGGGTCAGGTTCTTCAGACTCGACCGCTGGGCCGACGTGCGGTTCCCAGA AAAGAGGAGAATGAAGCTGGGGTCAGATATCAGCAAACACCACAAGTCACTGCTAGCCAA GATCTTTTATGACAGGGCTGAGTATCTTCATGGGAAACATGGTGTGGATGTGGAAGTCCA GGGGCCCCATGAAGCCCGAGATGGGCAGCTCCTTATCCGCCTGGATTTGAACCGCAAAGA GGTGCTGACCCTGAGGCTTCGGAATGGCGGAACCCAGTCTGTTACCCTCACTCACCTCTT CCCACTCTGCCGGACACCCCAGTTTGCTTTCTACAATGAAGACCAGGAGTTGCCCTGTCC ACTGGGCCCCGGTGAATGCTATGAACTCCATGTCCATTGTAAGACCAGCTTTGTGGGCTA CTTCCCAGCCACAGTGCTCTGGGAGCTGCTGGGACCTGGGGAGTCGGGTTCAGAAGGAGC CGGCACATTCTACATTGCCCGCTTCTTGGCTGCCGTCGCCCACAGCCCCCTGGCTGCACA GCTGAAGCCCATGACTCCCTTCAAGCGGACCCGGATCACCGGAAACCCTGTGGTGACCAA TCGGATAGAGGAAGGAGAGAGACCTGACCGCGCTAAGGGCTATGACCTGGAGTTAAGTAT GGCGCTGGGGACATACTACCCACCTCCCCGCCTCAGGCAGCTGCTCCCCATGCTTCTTCA GGGAACAAGTATCTTCACTGCCCCTAAGGAGATCGCAGAGATCAAGGCCCAGCTGGAGAC AGCCCTGAAGTGGAGGAACTATGAGGTGAAGCTGCGGCTGCTGCTGCACCTGGAGGAACT GCAGATGGAGCATGATATCCGGCACTATGACCTGGAGTCGGTGCCCATGACCTGGGACCC TGTGGACCAGAACCCCAGGCTGCTCACGCTGGAGGTTCCTGGAGTGACTGAGAGCCGCCC CTCAGTGCTACGGGGCGACCACCTGTTTGCCCTTTTGTCCTCGGAGACACACCAGGAGGA CCCCATCACATATAAGGGCTTTGTGCACAAGGTGGAATTGGACCGTGTCAAGCTGAGCTT TTCCATGAGCCTCCTGAGCCGCTTTGTGGATGGGCTGACCTTCAAGGTGAACTTTACCTT CAACCGCCAGCCGCTGCGAGTCCAGCACCGTGCCCTGGAGCTGACAGGGCGCTGGCTGCT GTGGCCCATGCTCTTTCCTGTGGCACCTCGGGACGTCCCGCTGCTGCCCTCAGATGTGAA ACTCAAGCTGTACGACCGGAGTCTGGAGTCAAACCCAGAGCAGCTGCAGGCCATGAGGCA CATTGTTACGGGCACCACCCGTCCAGCCCCCTACATCATCTTTGGGCCTCCAGGCACCGG CAAGACTGTCACGTTAGTGGAGGCAATTAAGCAGGTGGTGAAGCACTTGCCCAAAGCCCA CATCTTGGCCTGCGCTCCATCCAACTCAGGGGCTGACCTACTCTGTCAAAGGCTCCGGGT CCACCTTCCTAGCTCCATCTACCGCCTCCTGGCCCCCAGCAGGGACATCCGCATGGTACC TGAGGACATCAAGCCCTGCTGCAACTGGGACGCAAAGAAGGGGGAGTATGTATTTCCCGC CAAGAAGAAGCTGCAGGAATACCGGGTCTTAATTACCACCCTCATCACTGCCGGCAGGTT GGTCTCGGCCCAGTTTCCCATTGATCACTTCACACACATCTTCATCGATGAGGCTGGCCA CTGCATGGAGCCTGAGAGTCTGGTAGCTATAGCAGGGCTGATGGAAGTAAAGGAAACAGG TGATCCAGGAGGGCAGCTGGTGCTGGCAGGAGACCCTCGGCAGCTGGGGCCTGTGCTGCG TTCCCCACTGACCCAGAAGCATGGACTGGGATACTCACTGCTGGAGCGGCTGCTCACCTA CAACTCCCTGTACAAGAAGGGCCCTGATGGCTATGACCCCCAGTTCATAACCAAGCTGCT CCGCAACTACAGGTCTCATCCCACCATCCTGGACATTCCTAACCAGCTCTATTATGAAGG GGAGCTGCAGGCCTGTGCTGATGTCGTGGATCGAGAACGCTTCTGCCGCTGGGCGGGCCT ACCTCGACAGGGCTTTCCCATCATCTTTCACGGCGTAATGGGCAAAGATGAGCGTGAAGG CAACAGCCCATCCTTCTTCAACCCTGAAGAGGCTGCCACAGTGACTTCCTACCTGAAGCT GCTCCTGGCCCCCTCCTCCAAGAAGGGCAAAGCTCGCCTGAGCCCTCGAAGTGTGGGCGT CATCTCCCCGTACCGGAAACAGGTGGAGAAAATCCGTTACTGCATCACCAAACTTGACAG GGAGCTTCGAGGACTGGATGACATCAAGGACTTGAAGGTGGGTTCAGTAGAAGAATTCCA AGGCCAAGAACGAAGCGTCATCCTCATCTCCACCGTGCGAAGCAGCCAGAGCTTTGTGCA GCTGGATCTGGACTTTAATCTGGGTTTCCTTAAGAACCCCAAGAGGTTCAATGTAGCTGT GACCCGGGCCAAGGCCCTGCTCATCATCGTGGGGAACCCCCTTCTCCTGGGCCATGACCC TGACTGGAAAGTATTCCTGGAGTTCTGTAAAGAAAACGGAGGGTATACCGGGTGTCCCTT CCCTGCCAAACTGGACCTGCAACAGGGACAGAATTTACTGCAAGGTCTGAGCAAGCTCAG CCCCTCTACCTCAGGGCCCCACAGCCATGACTACCTCCCCCAGGAGCGGGAGGGTGAAGG GGGCCTGTCTCTGCAAGTGGAGCCAGAGTGGAGGAATGAGCTCTGAAGACACAGCACCCA GCCTTCTCGCACCAGCCAAGCCTTAACTGCCTGCCTGACCCTGAACCAGAACCCAGCTGA ACTGCCCCTCCAAGGGACAGGAAGGCTGGGGGAGGGAGTTTACAACCCAAGCCATTCCAC CCCCTCCCCTGCTGGGGAGAATGACACATCAAGCTGCTAACAATTGGGGGAAGGGGAAGG AAGAAAACTCTGAAAACAAAATCTTGTTCTATGCAAAAAAAAAAAAAAAAAA >OriGene 5' read for BC009312 unedited
NAAGTCAAAATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGNAGGGAA AGCTCAGGGCCGCCAACTTCCAGCTGCAGCGGCGACTTTCAGTTTCATTTCCACGGACCC TCCTGCCTGGGCCGCAGCCGCCGCCGCGATGCCCAGTAAGTTCAGCTGCCGGCAGCTCCG GGAGGCGGGCCAGTGTTTCGAGAGTTTCCTGGTCGTTCGGGGACTGGACATGGAGACAGA TCGCGAGCGGCTGCGGACCATTTATAACCGCGACTTCAAGATCAGCTTTGGGACCCCCGC CCCTGGCTTCTCCTCCATGCTGTATGGAATGAAGATTGCAAATCTGGCCTACGTCACCAA GACTCGGGTCAGGTTCTTCAGACTCGACCGCTGGGCCGACGTGCGGTTCCCAGAAAAGAG GAGAATGAAGCTGGGGTCAGATATCAGCAAACACCACAAGTCACTGCTAGCCAAGATCTT TTATGACAGGGCTGAGTATCTTCATGGGAAACATGGTGTGGATGTGGAAGTCCAGGGGCC CCATGAAGCCCGAGATGGGCAGCTCCTTATCCGCCTGGATTTGAACCGCAAAGAGGTGCT GACCCTGAGGCTTCGGAATGGCGGAACCCAGTCTGTTACCCTCACTCACCTCTTCCCACT CTGCCGGACACCCCAGTTTGCTTTCTACAATGAAGACCAGGAGTTGCCCTGTCCACTGGG CCCCGGTGAATGCTATGAACTCCATGTCCATTGTAAGACCAGCTTTGTGGGCTACTTCCC AGCCACAGTGCTCTGGGAGCTGCTGGGACCTGGGGAGTCNGGTTCAGAAGGAGCCGCACA TTCTACATTGCCGCTTCTTGCTGCCGTCGCCCAAGCCCCCTGGCTGACAGCTGAAGCCAT GACTCCCTTCA |
| Restriction Sites | Please inquire |
| ACCN | BC009312 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | BC009312.2, AAH09312.1 |
| RefSeq Size | 3352 bp |
| Locus ID | 4343 |
| Gene Summary | 5' to 3' RNA helicase contributing to UPF1 mRNA target degradation by translocation along 3' UTRs (PubMed:24726324). Required for microRNA (miRNA)-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC (PubMed:16289642, PubMed:17507929, PubMed:22791714). In cooperation with FMR1, regulates miRNA-mediated translational repression by AGO2 (PubMed:25464849). Restricts retrotransposition of long interspersed element-1 (LINE-1) in cooperation with TUT4 and TUT7 counteracting the RNA chaperonne activity of L1RE1 (PubMed:30122351, PubMed:23093941). Facilitates LINE-1 uridylation by TUT4 and TUT7 (PubMed:30122351). Required for embryonic viability and for normal central nervous system development and function. Plays two critical roles in early brain development: suppresses retroelements in the nucleus by directly inhibiting cDNA synthesis, while regulates cytoskeletal mRNAs to influence neurite outgrowth in the cytosol (By similarity). May function as a messenger ribonucleoprotein (mRNP) clearance factor (PubMed:24726324).[UniProtKB/Swiss-Prot Function] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
The Zinc-Finger Antiviral Protein ZAP Inhibits LINE and Alu Retrotransposition
,Moldovan, JB;Moran, JV;,
PLoS Genet.
,PubMed ID 25951186
[MOV10]
|
|
Perturbation of the P-Body Component Mov10 Inhibits HIV-1 Infectivity
,null,
PLoS ONE
,PubMed ID 20140200
[MOV10]
|
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