PHC1 (NM_004426) Human Untagged Clone
CAT#: SC127500
PHC1 (untagged)-Human polyhomeotic homolog 1 (Drosophila) (PHC1)
CNY 7,000.00
Cited in 1 publication. |
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | EDR1; HPH1; MCPH11; RAE28 |
Vector | pCMV6-XL4 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF within SC127500 sequence for NM_004426 edited (data generated by NextGen Sequencing)
ATGGAGACTGAGAGCGAGCAGAACTCCAATTCCACCAATGGGAGTTCTAGCTCAGGGGGC AGCTCTCGGCCCCAGATAGCTCAAATGTCACTATATGAACGACAAGCAGTGCAGGCTCTG CAAGCACTGCAGCGGCAGCCCAATGCAGCTCAGTATTTCCACCAGTTCATGCTCCAGCAG CAGCTCAGTAATGCCCAGCTGCATAGCCTGGCTGCCGTCCAGCAGGCCACAATTGCTGCC AGTCGGCAGGCCAGCTCCCCAAACACCAGCACTACACAGCAGCAGACTACCACCACCCAG GCCTCGATCAATCTGGCCACCACATCGGCCGCCCAGCTCATCAGCCGATCCCAGAGTGTG AGCTCTCCCAGTGCTACCACCTTGACCCAATCTGTGCTACTGGGGAACACCACCTCCCCA CCCCTCAACCAGTCTCAGGCCCAGATGTATCTACGGCCACAGCTGGGAAACCTATTGCAG GTAAACCGAACCCTGGGTCGGAATGTGCCTCTAGCCTCCCAACTCATCCTGATGCCTAAT GGGGCGGTGGCTGCAGTCCAGCAGGAGGTGCCATCTGCTCAGTCTCCTGGAGTTCATGCA GATGCAGATCAGGTTCAGAACTTGGCAGTAAGGAATCAACAGGCCTCAGCTCAAGGACCT CAGATGCAAGGCTCCACTCAGAAGGCCATTCCTCCAGGAGCCTCCCCTGTCTCTAGCCTC TCCCAGGCCTCTAGCCAGGCCCTAGCGGTGGCACAGGCTTCCTCTGGGGCCACAAACCAG TCCCTCAACCTTAGTCAAGCTGGTGGAGGCAGTGGGAATAGCATCCCAGGGTCCATGGGT CCAGGTGGAGGTGGGCAGGCACATGGTGGTTTGGGTCAGTTGCCTTCCTCAGGAATGGGT GGTGGGAGCTGTCCCAGGAAGGGTACAGGAGTGGTGCAGCCCTTGCCTGCAGCCCAAACA GTGACTGTGAGCCAGGGCAGCCAGACAGAGGCAGAAAGTGCAGCAGCCAAGAAGGCAGAA GCAGATGGGAGTGGCCAGCAGAATGTGGGCATGAACCTGACACGGACAGCCACACCTGCG CCCAGCCAGACACTTATTAGCTCAGCCACCTACACACAGATCCAGCCCCATTCACTGATT CAGCAACAGCAACAGATCCACCTCCAGCAGAAACAGGTGGTGATCCAGCAGCAGATTGCC ATCCACCACCAGCAGCAGTTCCAGCACCGGCAGTCCCAGCTCCTTCACACAGCTACACAC CTCCAGTTGGCGCAGCAGCAGCAGCAGCAACAACAGCAACAGCAGCAACAGCAGCAGCCG CAAGCCACCACCCTCACTGCCCCTCAGCCACCACAGGTCCCACCTACTCAGCAGGTCCCA CCTTCCCAGTCCCAGCAGCAAGCCCAAACCCTGGTCGTTCAGCCCATGCTTCAGTCTTCA CCCTTGTCTCTTCCACCTGATGCAGCCCCTAAGCCACCAATTCCCATCCAATCCAAACCA CCTGTAGCACCTATCAAGCCGCCTCAGTTAGGGGCCGCTAAGATGTCAGCTGCCCAGCAA CCACCACCCCATATCCCTGTGCAAGTTGTAGGCACTCGACAGCCAGGTACAGCCCAGGCA CAGGCTTTGGGGTTGGCACAGCTGGCAGCTGCTGTACCTACTTCCCGGGGGATGCCAGGT ACAGTGCAGTCTGGTCAGGCCCATTTGGCCTCCTCGCCACCTTCATCCCAGGCTCCTGGT GCACTGCAGGAGTGCCCTCCCACATTGGCCCCTGGGATGACCCTTGCTCCTGTGCAGGGG ACAGCACATGTGGTAAAGGGTGGGGCTACCACCTCCTCACCTGTTGTAGCCCAGGTCCCT GCTGCCTTCTATATGCAGTCTGTGCACTTGCCGGGTAAACCCCAGACATTGGCTGTCAAA CGCAAGGCTGACTCTGAGGAGGAGAGAGATGATGTCTCCACATTGGGTTCAATGCTTCCT GCCAAGGCATCTCCAGTAGCAGAAAGCCCAAAAGTCATGGACGAGAAGAGCAGTCTTGGA GAAAAAGCTGAATCAGTGGCTAATGTGAATGCTAATACTCCAAGCAGTGAACTAGTAGCC TTGACCCCCGCCCCTTCAGTACCGCCTCCTACACTAGCCATGGTGTCTAGACAAATGGGT GACTCAAAACCCCCACAGGCCATCGTGAAGCCCCAGATTCTCACCCACATCATTGAAGGC TTTGTTATCCAGGAAGGAGCAGAACCTTTCCCGGTGGGTTGTTCTCAGTTACTGAAGGAG TCTGAGAAGCCACTACAGACTGGCCTTCCGACAGGGCTGACTGAGAATCAGTCAGGTGGC CCTTTGGGAGTGGACAGCCCATCTGCTGAGTTAGATAAGAAGGCGAATCTCCTGAAGTGC GAGTACTGTGGGAAGTACGCCCCCGCAGAGCAGTTTCGTGGCTCTAAGAGGTTCTGCTCC ATGACTTGCGCTAAGAGGTACAATGTGAGCTGTAGCCATCAGTTCCGGCTGAAGAGGAAA AAAATGAAAGAGTTTCAAGAAGCCAACTATGCTCGCGTTCGCAGGCGTGGACCCCGCCGC AGCTCCTCTGACATTGCCCGTGCCAAGATTCAGGGCAAGTGCCACCGGGGTCAAGAAGAC TCTAGCCGGGGTTCAGATAATTCCAGTTATGATGAAGCACTCTCTCCAACATCTCCTGGG CCTTTATCAGTAAGAGCTGGGCATGGAGAACGTGACCTGGGGAATCCCAATACAGCTCCA CCTACACCGGAATTACATGGCATCAACCCTGTGTTCCTGTCCAGTAATCCCAGCCGTTGG AGTGTAGAGGAGGTGTACGAGTTTATTGCTTCTCTCCAAGGCTGCCAAGAGATTGCAGAG GAATTTCGCTCACAGGAGATTGATGGACAGGCCCTTTTATTACTTAAAGAAGAACATCTT ATGAGTGCCATGAACATCAAGCTGGGCCCTGCCCTCAAGATCTGCGCCAAGATAAATGTC CTCAAGGAGACCTAA Clone variation with respect to NM_004426.2 93 t=>a;918 a=>g >OriGene 5' read for NM_004426 unedited
TATAGGCGGCCGCGAATTCGGCACGAGGCTCGTGTCTCTGAGTCCAGTGAACTAAATCCA GTAATCTATAAAACTGTGCCGTGCTGCCTCTAATCCTTACCCACTTTTTTTCTTCACATG CTGATAATGAGGATTCATGGGTCTTGAGTCAGACAGAGCACCAGCCTTGGGGACCCTGGA CCACTATCATGGAGACTGAGAGCGAGCAGAACTCCAATTCCACCAATGGGAGTTCTAGCT CAAGGGGCAGCTCTCGGCCCCAGATAGCTCAAATGTCACTATATGAACGACAAGCAGTGC AGGCTCTGCAAGCACTGCAGCGGCAGCCCAATGCAGCTCAGTATTTCCACCAGTTCATGC TCCAGCAGCAGCTCAGTAATGCCCAGCTGCATAGCCTGGCTGCCGTCCAGCAGGCCACAA TTGCTGCCAGTCGGCAGGCCAGCTCCCCAAACACCAGCACTACACAGCAGCAGACTACCA CCACCCAGGCCTCGATCAATCTGGCCACCACATCGGCCGCCCAGCTCATCAGCCGATCCC AGAGTGTGAGCTCTCCCAGTGCTACCACCTTGACCCAATCTGTGCTACTGGGGAACACCA CCTCCCCACCCCTCAACCAGTCTCAGGCCCAGATGTATCTACGGCCACAGCTGGGANACC TATTGCAGGTAAACCGAACCCTGGGTCGGAATGTGCCTCTAGCCTNCCAACTCATNCTGA TGCCTATGGGGGCGGTGGCTGCAGTCCAGCAGGAGGTGCCATCTGCTCAGTCTCCTGGAG TCATGCAATGCAGNACAGGTTCAGAACTTGCAGTAGGGAATCACAGGCCTCAGCTCAGGG ACCTCANATGCAGGCTCACTCAAAAGGCATTNNCTCAGAGCTNCCTGCTTGAANNCCTTC CAGGCTNTAGCAG >OriGene 3' read for NM_004426 unedited
NNTTACTTGNCCGCGGCCGCAATCTANGATCGAGTTTTTTTTTTTTTTTTTTTTTACTGA GGAAAAAAAATTTAATATTTTTGTTATATAAGGAATAGTGCCTAAGGCAGGTACTTATAC TCCTGACCTCAGCCCCACACACTCTGGTTTTATAAAGCTATAGGACAGAGCAGAGATGGA ACTGAAAAACAGGGTAGAAAATAACATAAATTGGAGGGGAACAGTGGGATGCAGAAAGAA TGACAACAGCCACATGTGCCCCAGTCAAATACTTTTAGTCCCTGCAGCAGAAGATGCCAA CCAAGTCTCTATACTGGCTGGGGATCCTGCCATGGATGCAGGAGAAAAAATTCAATCACA AGGGAGTAAGTGACAACAAAAAGAAAAAACTCTGAGCCACAGCTACACTGGGAGGGGGGA GGACCAGATTTTGCTACTTCTGTCACACAAGCTAGAAAAACCCTACCTCTCCCATTGGGC AGGCAACCTGACATTCCACCCAGTTCCTTGCCTTACCATACTATGTATTCCTCCTCTTGG AGAATTAAGACCTGGGCTAAATGCTCCACTCCAGGATAAGGCTGAGCAGTCCTAGTTCTC TAGACTGCCTCTTTTATAAAGATTGGATTAAGGTACGTGAAATGGTGAGAACTGTAAAGA TTTTAAAAAATAAAGTAGAACCCAGAGAAAATGTCAAAGCTGCCGCCATGTAGCACCAGC AACCAATTCTTGCACTTCTCTTCCCTGTCTCAGTAATCCCCTACAGAAGGTTACATGATT GGGACAACTCTTNTCTTCCCTGCAAGTCTGCTGGTACCCAGTTATACCTGGACAGGGGAN AGTGTCTGCCTTAGCTGGTNTGTGCAAGAGGCCCACCCTAGTCTNNCTGAGACATTNNAT CTGGCGCAGATCTTGAGGCAGGNCCCAGCTGATGTCATGGACTCATAA |
Restriction Sites | NotI-NotI |
ACCN | NM_004426 |
Insert Size | 4100 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_004426.2, NP_004417.2 |
RefSeq Size | 5206 bp |
RefSeq ORF | 3015 bp |
Locus ID | 1911 |
UniProt ID | P78364 |
Domains | SAM |
Protein Families | ES Cell Differentiation/IPS, Stem cell - Pluripotency |
Gene Summary | This gene is a homolog of the Drosophila polyhomeotic gene, which is a member of the Polycomb group of genes. The gene product is a component of a multimeric protein complex that contains EDR2 and the vertebrate Polycomb protein BMH1. The gene product, the EDR2 protein, and the Drosophila polyhomeotic protein share 2 highly conserved domains, named homology domains I and II. These domains are involved in protein-protein interactions and may mediate heterodimerization of the protein encoded by this gene and the EDR2 protein. [provided by RefSeq, Jul 2008] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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Mutation in PHC1 implicates chromatin remodeling in primary microcephaly pathogenesis
,Salma Awad, Mohammed S Al-Dosari, Nadya Al-Yacoub, Dilek Colak, Mustafa A Salih, Fowzan S Alkuraya, and Coralie Poizat,
Hum. Mol. Genet., Jun 2013; 22: 2200 - 2213.
,PubMed ID 23418308
[PHC1]
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC222530 | PHC1 (Myc-DDK-tagged)-Human polyhomeotic homolog 1 (Drosophila) (PHC1) |
CNY 6,992.00 |
|
RC222530L1 | Lenti ORF clone of Human polyhomeotic homolog 1 (Drosophila) (PHC1), Myc-DDK-tagged |
CNY 9,392.00 |
|
RC222530L2 | Lenti ORF clone of Human polyhomeotic homolog 1 (Drosophila) (PHC1), mGFP tagged |
CNY 12,540.00 |
|
RC222530L3 | Lenti ORF clone of Human polyhomeotic homolog 1 (Drosophila) (PHC1), Myc-DDK-tagged |
CNY 12,540.00 |
|
RC222530L4 | Lenti ORF clone of Human polyhomeotic homolog 1 (Drosophila) (PHC1), mGFP tagged |
CNY 12,540.00 |
|
RG222530 | PHC1 (tGFP-tagged) - Human polyhomeotic homolog 1 (Drosophila) (PHC1) |
CNY 8,592.00 |