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Neurexin 1 (NRXN1) (NM_004801) Human Untagged Clone
CAT＃: SC127539
NRXN1 (untagged)-Human neurexin 1 (NRXN1), transcript variant alpha1
CNY 10,112.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | Hs.22998; PTHSL2; SCZD17 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_004801, the custom clone sequence may differ by one or more nucleotides
ATGGGGACGGCGCTGCTCCAGCGCGGGGGCTGTTTTCTTCTGTGCCTCTCGCTGCTGCTCCTGGGCTGCT GGGCGGAGCTGGGCAGCGGGCTGGAGTTTCCGGGCGCCGAGGGCCAATGGACGCGCTTCCCCAAGTGGAA CGCCTGCTGCGAGAGCGAGATGAGCTTCCAGCTCAAGACTCGCAGCGCCCGCGGCCTCGTGCTCTACTTC GACGACGAGGGCTTCTGCGACTTCCTGGAGCTGATTCTGACGCGCGGCGGCCGCCTGCAGCTCAGCTTCT CCATCTTCTGCGCTGAGCCTGCGACGCTCCTGGCCGACACGCCGGTTAACGACGGCGCCTGGCACAGCGT GCGCATCCGCCGCCAGTTCCGCAACACCACGCTCTTCATCGACCAGGTGGAGGCCAAGTGGGTGGAGGTC AAGTCCAAGCGCAGGGACATGACGGTGTTCAGCGGCCTTTTCGTCGGGGGGCTGCCCCCGGAACTGCGCG CCGCGGCGCTCAAGCTCACCCTGGCCTCGGTGAGGGAGCGGGAGCCCTTCAAGGGGTGGATTCGTGACGT GAGGGTCAACTCCTCGCAGGTCCTGCCCGTGGACAGCGGCGAGGTGAAGCTGGACGATGAGCCGCCCAAC AGCGGCGGGGGAAGCCCGTGCGAGGCGGGCGAGGAGGGCGAGGGCGGGGTGTGCCTCAACGGAGGTGTGT GCTCCGTGGTGGACGACCAGGCCGTGTGCGACTGCTCGCGAACCGGCTTCCGCGGCAAGGACTGCAGCCA AGAAGACAACAATGTGGAAGGTCTGGCGCACCTGATGATGGGCGACCAAGGTAAAAGTAAAGGAAAAGAA GAATATATTGCCACGTTCAAAGGATCTGAATACTTCTGCTACGACTTGTCTCAAAACCCCATTCAAAGCA GCAGTGATGAAATAACTCTGTCATTTAAAACCCTTCAGAGGAATGGACTGATGCTTCACACTGGGAAATC GGCTGATTATGTCAATCTTGCCCTGAAAAATGGAGCTGTCTCTCTGGTCATTAATTTGGGATCAGGGGCC TTTGAAGCACTAGTGGAGCCTGTGAATGGAAAGTTTAATGATAATGCCTGGCATGATGTGAAAGTCACCA GGAATCTGCGTCAGCACTCAGGCATTGGACACGCTATGGTGACAATATCAGTGGATGGGATTCTTACCAC AACGGGCTACACGCAAGAAGATTATACCATGCTGGGGTCTGATGACTTTTTCTATGTTGGAGGCAGTCCC AGCACAGCCGACCTTCCAGGGTCACCAGTCAGTAACAACTTTATGGGCTGTCTCAAAGAGGTTGTATATA AAAATAATGATGTGAGGCTGGAATTATCTCGACTTGCCAAGCAAGGAGATCCTAAGATGAAGATCCATGG AGTGGTGGCATTTAAATGTGAGAATGTTGCAACTTTAGACCCAATCACCTTTGAAACCCCAGAGTCTTTC ATCTCTTTGCCTAAATGGAATGCAAAGAAAACTGGCTCCATATCATTTGATTTCCGTACAACAGAGCCAA ATGGCCTCATCTTATTTAGCCATGGCAAGCCAAGACATCAGAAAGATGCCAAGCACCCACAGATGATAAA GGTGGACTTCTTTGCTATTGAGATGCTAGATGGCCACCTCTACCTCCTCCTGGACATGGGGTCAGGTACT ATAAAAATAAAAGCCCTGTTGAAGAAAGTGAATGATGGAGAATGGTATCATGTGGACTTCCAGAGAGACG GACGGTCAGGTACCATTTCTGTCAACACGTTGCGTACTCCCTACACTGCTCCTGGTGAGAGTGAGATTCT GGACCTGGATGATGAGTTGTACCTGGGGGGGCTGCCAGAAAATAAAGCTGGCCTTGTCTTCCCCACCGAG GTGTGGACTGCTCTGCTCAACTATGGCTACGTGGGCTGCATCAGGGATTTGTTCATCGATGGCCAAAGCA AAGATATCCGGCAAATGGCTGAAGTTCAAAGTACTGCTGGAGTGAAGCCTTCCTGCTCAAAGGAAACAGC AAAACCGTGCCTTAGCAACCCTTGCAAAAACAATGGCATGTGCAGGGATGGGTGGAACAGATATGTCTGT GATTGTTCCGGAACAGGCTATCTTGGCAGGTCCTGTGAGAGAGAGGCAACGGTTTTGAGCTATGATGGGA GCATGTTTATGAAAATTCAGCTCCCCGTAGTCATGCATACGGAGGCTGAGGATGTTTCCTTACGGTTCCG ATCCCAGCGTGCATATGGCATTCTGATGGCAACCACTTCTAGAGACTCTGCTGACACCCTCCGCCTGGAG CTAGACGCAGGACGTGTGAAACTGACGGTCAATCTAGATTGTATCAGGATTAACTGTAATTCCAGCAAAG GTCCCGAGACTCTTTTTGCTGGCTATAACCTCAATGATAACGAGTGGCACACAGTGCGTGTAGTTCGGCG TGGAAAAAGTTTAAAGTTAACAGTGGATGACCAACAGGCCATGACAGGTCAAATGGCAGGTGATCATACT AGGCTGGAGTTCCATAACATAGAGACTGGCATCATCACAGAACGACGGTATCTTTCTTCTGTCCCCTCCA ACTTCATTGGACACCTGCAGAGCTTGACATTTAATGGAATGGCATACATTGACCTGTGTAAAAATGGCGA CATAGATTACTGTGAGCTTAATGCCAGATTTGGCTTCAGGAACATCATAGCAGATCCTGTCACCTTCAAG ACCAAATCGAGCTATGTTGCCTTAGCTACCTTGCAAGCCTACACTTCTATGCATCTTTTTTTCCAGTTCA AGACAACATCCCTAGATGGATTAATTCTATATAACAGTGGGGATGGAAATGACTTTATTGTGGTTGAATT AGTTAAAGGGTACTTACATTACGTGTTTGATTTGGGAAATGGTGCTAACCTCATCAAAGGAAGCTCAAAT AAACCTCTCAATGACAATCAGTGGCACAACGTGATGATATCAAGGGACACCAGCAACCTCCACACTGTAA AGATTGACACAAAAATCACAACGCAAATCACCGCCGGAGCCAGGAACTTAGACCTCAAGAGTGACTTATA TATAGGAGGAGTAGCTAAAGAAACATACAAATCCTTACCAAAACTTGTACATGCCAAAGAAGGCTTTCAA GGCTGCCTGGCATCAGTTGATTTAAATGGACGGCTTCCGGACCTCATCTCCGATGCTCTTTTCTGCAACG GACAGATCGAGAGAGGATGTGAAGGGCCCAGCACAACCTGCCAAGAGGACTCATGTTCCAATCAAGGTGT GTGCTTGCAACAATGGGATGGCTTCAGCTGTGACTGTAGTATGACTTCCTTCAGTGGACCACTCTGCAAT GACCCTGGGACGACATATATCTTTAGCAAAGGTGGTGGACAAATCACGTATAAGTGGCCTCCTAATGACC GACCCAGTACACGAGCAGACAGACTGGCCATAGGTTTTAGCACTGTTCAGAAAGAAGCCGTATTGGTGCG AGTGGACAGTTCTTCAGGCTTGGGTGACTACCTAGAACTGCATATACACCAGGGAAAAATTGGAGTTAAG TTTAATGTTGGGACAGATGACATCGCCATTGAAGAATCCAATGCAATCATTAATGATGGGAAATACCATG TAGTTCGTTTCACGAGGAGTGGTGGCAATGCCACGTTGCAGGTGGACAGCTGGCCAGTGATCGAGCGCTA CCCTGCAGGGCGTCAGCTCACAATCTTCAATAGCCAAGCAACCATAATAATTGGCGGGAAAGAGCAGGGC CAGCCCTTCCAGGGCCAGCTCTCTGGGCTGTACTACAATGGCTTGAAAGTTCTGAATATGGCAGCCGAAA ACGATGCCAACATCGCCATAGTGGGAAATGTGAGACTGGTTGGTGAAGTGCCTTCCTCTATGACAACTGA GTCAACAGCCACTGCCATGCAATCAGAGATGTCCACATCAATTATGGAGACTACCACGACCCTGGCTACT AGCACAGCCAGAAGAGGAAAGCCCCCGACAAAAGAACCCATTAGCCAGACCACAGATGACATCCTTGTGG CCTCAGCAGAGTGTCCCAGCGATGATGAGGACATTGACCCCTGTGAGCCGAGCTCAGGTGGGTTAGCCAA CCCAACCCGAGCAGGCGGCAGAGAGCCGTATCCAGGCTCAGCAGAAGTGATCCGGGAGTCCAGCAGCACC ACGGGTATGGTCGTTGGGATAGTAGCCGCTGCCGCCCTGTGCATCCTTATCCTCCTCTATGCCATGTACA AGTACAGAAACCGGGATGAAGGCTCATACCATGTGGACGAGAGTCGAAACTACATCAGTAACTCAGCACA GTCCAATGGGGCTGTTGTAAAGGAGAAACAACCCAGCAGTGCGAAAAGCTCCAACAAAAATAAGAAAAAC AAGGATAAAGAGTATTATGTCTGA >OriGene 5' read for NM_004801 unedited
CCCCCCCCCNNNNNCCNCCCNCCTTTTCCCCCCCNCNNGGTTCGGAATTTGTNATACCAC TCACTATAGGCGGCCGCGNAATTCGCACGNAGGNANANANAGAGAGAGAGAGAACTAGAT AAAGGAGGGCACATCCCTCTCACTCCCGCCTTTCCCCTTACCTTTCTGTCTCTCGGGACC CTTATTTCTTCGTCACGGTGTCCAGGACCATTTTGACCCTGTCGGCCCCGGCACCCCCCC GCCGCACCCCAGCCCCGAGCATGGGGACGGCGCTGCTCCAGCGCGGGGGCTGTTTTCTTC TGTGCCTCTCGCTGCTGCTCCTGGGCTGCTGGGCGGAGCTGGGCAGCGGGCTGGAGTTTC CGGGCGCCGAGGGCCAATGGACGCGCTTCCCCAAGTGGAACGCCTGCTGCGAGAGCGAGA TGAGCTTCCAGCTCAAGACTCGCAGCGCCCGCGGCCTCGTGCTCTACTTCGACGACGAGG GCTTCTGCGACTTCCTGGAGCTGATTCTGACGCGCGGCGGCCGCCTGCAGCTCAGCTTCT CCATCTTCTGCGCTGAGCCTGCGACGCTCCTGGCCGACACGCCGGTTAACGACGGCGCCT GGCACAGCGTGCGCATCCGCCGCCAGTTCCGCAACACCACGCTCTTCATCGACCAGGTGG AGGCCAAGTGGGTGGAGGTCAAGTCCAAGCGCAGGGACATGACGGTGTTCAGCGGCCTTT TCGTCGGGGGGCTGCCCCCGGAACTGCGCGCCGCGGCGCTCAAGCTCACCTTGGCCTCGG TGAGGGAGCGGGAGCCCTTCAGGGGTGGATTCGNGACGTGAGGGCACCTCCTCGCAGGTC TGCCCCGTGACAGGGCGAGGTGAAGCTGGACGATGACCCCCCAACACCGGCGGGGAAGCC CCCTCTAGCGGCCCAGAGGGCCAGGCCCGGGTGTGCCTTAACGGGGGGGGTGCTCCGGGG GGACCACCAGCG >OriGene 3' read for NM_004801 unedited
TTTTTATGTACCGCGGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTGAGAAAC AAGACATGAGATACTTGTTTTTATTTTTTAAAAAGTCTTTCCTTCCTGATTGCATTCCCT GTCTTCTTTTGTATGTGCTTCATAAAAAGGAAAGTAAATAAGTTTATATTATGTCTCAGA TAAAATGAAGACTATTTCTATACAAGTGTCCATTTAAGATCTTGGGATCAGACATAATAC TCTTTATCCTTGTTTTTCTTATTTTTGTTGGAGCTTTTCGCACTGCTGGGTTGTTTCTCC TTTACAACAGCCCCATTGGACTGTGCTGAGTTACTGATGTAGTTTCGACTCTCGTCCACA TGGTATGAGCCTTCATCCCGGTTTCTGTACTTGTACATGGCATAGAGGAGGATAAGGATG CACAGGGCGGCAGCGGCTACTATCCCAACGACCATACCCGTGGTGCTGCTGGACTCCCGG ATCACTTCTGCTGAGCCTGGATACGGCTCTCTGCCGCCTGCTCGGGTTGGGTTGGCTGAC CTCGGCTCACAGGGGACAATGCCCTCATCATCGCTGGGACCCTCTGCTGAGGCCCCAGGA TGACATCTGCGGACTGGCTAATGGGATCCTTTGCCGGGGCCCACCCCTTGTGCTGCGCTA ACCACCCGGATATGGTAACCCCATCATGCATGGGACAACACGTGACGCAAGGCAATGCCT CGTGACTTCCCTGTCGAAAGCAAGCCCTTCGGCGACCAGCCCCCCTCGTCCTTTAGGGGG ATGTATCTTTCTCTCATCGCCCATCCCCACTACCCACCCTTGTGTACCCCTCTCCCACCC TTACCACTAGGACGAACCTTATTTCCCCCCCTACGTTCCGCCCGCCGCCATCTCAAAGCC AACCCCGCGTCCTCCCGCCCCGCCCCCCCTCTACCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004801 |
| Insert Size | 4470 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_004801.2, NP_004792.1 |
| RefSeq Size | 9368 bp |
| RefSeq ORF | 4434 bp |
| Locus ID | 9378 |
| UniProt ID | Q9ULB1 |
| Domains | LamG, EGF, EGF |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Cell adhesion molecules (CAMs) |
| Gene Summary | This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca(2+)-dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission and is involved in the formation of synaptic contacts. Three members of this gene family have been studied in detail and are estimated to generate over 3,000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member. Recently, a third promoter (gamma) was identified for this gene in the 3' region. Mutations in this gene are associated with Pitt-Hopkins-like syndrome-2 and may contribute to susceptibility to schizophrenia. [provided by RefSeq, Aug 2016] Transcript Variant: This variant (alpha1) results from the use of the 5'-most promoter, referred to as alpha. It lacks two in-frame exons and uses an alternate in-frame donor splice site at an internal exon compared to variant alpha2. The resulting isoform (alpha1) is shorter missing a few internal protein segments compared to isoform alpha2. This isoform contains EGF-like, several laminin G, and syndecan domains. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC219376 | NRXN1 (Myc-DDK-tagged)-Human neurexin 1 (NRXN1), transcript variant alpha1 |
CNY 16,168.00 |
|
| RC219376L1 | Lenti-ORF clone of NRXN1 (Myc-DDK-tagged)-Human neurexin 1 (NRXN1), transcript variant alpha1 |
CNY 16,630.00 |
|
| RC219376L2 | Lenti-ORF clone of NRXN1 (mGFP-tagged)-Human neurexin 1 (NRXN1), transcript variant alpha1 |
CNY 18,568.00 |
|
| RC219376L3 | Lenti-ORF clone of NRXN1 (Myc-DDK-tagged)-Human neurexin 1 (NRXN1), transcript variant alpha1 |
CNY 16,630.00 |
|
| RC219376L4 | Lenti-ORF clone of NRXN1 (mGFP-tagged)-Human neurexin 1 (NRXN1), transcript variant alpha1 |
CNY 16,630.00 |
|
| RG219376 | NRXN1 (tGFP-tagged) - Human neurexin 1 (NRXN1), transcript variant alpha1 |
CNY 17,768.00 |
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