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EGR1 (NM_001964) Human Untagged Clone
CAT＃: SC128132
EGR1 (untagged)-Human early growth response 1 (EGR1)
CNY 6,072.00
| Cited in 10 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AT225; G0S30; KROX-24; NGFI-A; TIS8; ZIF-268; ZNF225 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_001964 edited
CAGCTCTCCAGCCTGCTCGTCCAGGATGGCCGCGGCCAAGGCCGAGATGCAGCTGATGTC CCCGCTGCAGATCTCTGACCCGTTCGGATCCTTTCCTCACTCGCCCACCATGGACAACTA CCCTAAGCTGGAGGAGATGATGCTGCTGAGCAACGGGGCTCCCCAGTTCCTCGGCGCCGC CGGGGCCCCAGAGGGCAGCGGCAGCAACAGCAGCAGCAGCAGCAGCGGGGGCGGTGGAGG CGGCGGGGGCGGCAGCAACAGCAGCAGCAGCAGCAGCACCTTCAACCCTCAGGCGGACAC GGGCGAGCAGCCCTACGAGCACCTGACCGCAGAGTCTTTTCCTGACATCTCTCTGAACAA CGAGAAGGTGCTGGTGGAGACCAGTTACCCCAGCCAAACCACTCGACTGCCCCCCATCAC CTATACTGGCCGCTTTTCCCTGGAGCCTGCACCCAACAGTGGCAACACCTTGTGGCCCGA GCCCCTCTTCAGCTTGGTCAGTGGCCTAGTGAGCATGACCAACCCACCGGCCTCCTCGTC CTCAGCACCATCTCCAGCGGCCTCCTCCGCCTCCGCCTCCCAGAGCCCACCCCTGAGCTG CGCAGTGCCATCCAACGACAGCAGTCCCATTTACTCAGCGGCACCCACCTTCCCCACGCC GAACACTGACATTTTCCCTGAGCCACAAAGCCAGGCCTTCCCGGGCTCGGCAGGGACAGC GCTCCAGTACCCGCCTCCTGCCTACCCTGCCGCCAAGGGTGGCTTCCAGGTTCCCATGAT CCCCGACTACCTGTTTCCACAGCAGCAGGGGGATCTGGGCCTGGGCACCCCAGACCAGAA GCCCTTCCAGGGCCTGGAGAGCCGCACCCAGCAGCCTTCGCTAACCCCTCTGTCTACTAT TAAGGCCTTTGCCACTCAGTCGGGCTCCCAGGACCTGAAGGCCCTCAATACCAGCTACCA GTCCCAGCTCATCAAACCCAGCCGCATGCGCAAGTACCCCAACCGGCCCAGCAAGACGCC CCCCCACGAACGCCCTTACGCTTGCCCAGTGGAGTCCTGTGATCGCCGCTTCTCCCGCTC CGACGAGCTCACCCGCCACATCCGCATCCACACAGGCCAGAAGCCCTTCCAGTGCCGCAT CTGCATGCGCAACTTCAGCCGCAGCGACCACCTCACCACCCACATCCGCACCCACACAGG CGAAAAGCCCTTCGCCTGCGACATCTGTGGAAGAAAGTTTGCCAGGAGCGATGAACGCAA GAGGCATACCAAGATCCACTTGCGGCAGAAGGACAAGAAAGCAGACAAAAGTGTTGTGGC CTCTTCGGCCACCTCCTCTCTCTCTTCCTACCCGTCCCCGGTTGCTACCTCTTACCCGTC CCCGGTTACTACCTCTTATCCATCCCCGGCCACCACCTCATACCCATCCCCTGTGCCCAC CTCCTTCTCCTCTCCCGGCTCCTCGACCTACCCATCCCCTGTGCACAGTGGCTTCCCCTC CCCGTCGGTGGCCACCACGTACTCCTCTGTTCCCCCTGCTTTCCCGGCCCAGGTCAGCAG CTTCCCTTCCTCAGCTGTCACCAACTCCTTCAGCGCCTCCACAGGGCTTTCGGACATGAC AGCAACCTTTTCTCCCAGGACAATTGAAATTTGCTAAAGGGAAAGGGGAAAGAAAGGGAA AAGGGAGAAAAAGAAACACAAGAGACTTAAAGGACAGGAGGAGGAGATGGCCATAGGAGA GGAGGGTTCCTCTTAGGTCAGATGGAGGTTCTCA >OriGene 5' read for NM_001964 unedited
AGGTTCAAATTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCTTCAGCTCTCCAGC CTGCTCGTCCAGATGGCCGCGGCCAAGGCCGAGATGCAGCTGATGTCCCCGCTGCAGATC TCTGACCCGTTCGGATCCTTTCCTCACTCGCCCACCATGGACAACTACCCTAAGCTGGAG GAGATGATGCTGCTGAGCAACGGGGCTCCCCAGTTCCTCGGCGCCGCCGGGGCCCCAGAG GGCAGCGGCAGCAACAGCAGCAGCAGCAGCAGCGGGGGCGGTGGAGGCGGCGGGGGCGGC AGCAACAGCAGCAGCAGCAGCAGCACCTTCAACCCTCAGGCGGACACGGGCGAGCAGCCC TACGAGCACCTGACCGCAGAGTCTTTTCCTGACATCTCTCTGAACAACGAGAAGGTGCTG GTGGAGACCAGTTACCCCAGCCAAACCACTCGACTGCCCCCCATCACCTATACTGGCCGC TTTTCCCTGGAGCCTGCACCCAACAGTGGCAACACCTTGTGGCCCGAGCCCCTCTTCAGC TTGGTCAGTGGCCTAGTGAGCATGACCAACCCACCGGCCTCCTCGTCCTCAGCACCATCT CCAGCGGCCTCCTCCGCCTCCGCCTCCCAGAGCCCACCCCTGAGCTGCGCAGTGCCATCC AACGACAGCAGTCCCATTTACTCAGCGGCACCCACCTTCCCCACGCCGAACACTGACATT TTCCCTGAGCCACAAAGCCAGGCCTTCCCGGGCTCGGCAGGGACAGCGCTCCAGTACCCG CCTCCTGCCTACCCTGCCGCCAAGGGTGGCTTTCAGGTTCCCATGATCCCCGACTACCTG TTTCCACAGCAGCAGGNGGATCTGGGCCTGGGCACCCCAGAACAGAAGCCCCTCCG >OriGene 3' read for NM_001964 unedited
TATGGGGTGGCACTTCCAGGNCCAGGNANAGCACTGGGGNAGGGTCACAGGGATGCCACC CGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGACAAGCTTGAT ATCGGTACCAGATCTGAATTCGGCTTGAGAACCTCCATCTGACCTAAGAGGAACCCTCCT CTCCTATGGCCATCTCCTCCTCCTGTCCTTTAAGTCTCTTGTGTTTCTTTTTCTCCCTTT TCCCTTTCTTTCCCCTTTCCCTTTAGCAAATTTCAATTGTCCTGGGAGAAAAGGTTGCTG TCATGTCCGAAAGCCCTGTGGAGGCGCTGAAGGAGTTGGTGACAGCTGAGGAAGGGAAGC TGCTGACCTGGGCCGGGAAAGCAGGGGGAACAGAGGAGTACGTGGTGGCCACCGACGGGG AGGGGAAGCCACTGTGCACAGGGGATGGGTAGGTCGAGGAGCCGGGAGAGGAGAAGGAGG TGGGCACAGGGGATGGGTATGAGGTGGTGGCCGGNGATGGATAAGAGGTAGTAACCGGGG ACGGGTAAGAGGTAGCAACCGGGGACGGGTAGGAAGAGAGAGAGGNANGTGGCCGAANAG GCCACAACACTTTTGTCTGCTTTCTTGTCCTTCTGCCGCAAGTGGATCTTGGTATGCCTC TTGCGTTCATCGCTCCTGGCAAACTTTCTTCCACAGATGTCGCAAGCGAAAGGCTTTTCG CCTGTGTGGGTGCCGATGTGGGTGGTGAAGGTGGTCCCTGCCGGCTGAAGTTGCCCATGC AAAATGCCGGACTGGAAAGGCCTCCGGGCCTGTGTGGATCCGGATAGTGCCCGGTGAGCT TCTCCGAACCGGGAAAAAACGGCCAATCCAGGACTCCACTGGGGCAAGCCGTAAGGCCGT TCCTGGGGGGGGCGTTCTGGG |
| Restriction Sites | Please inquire |
| ACCN | NM_001964 |
| Insert Size | 1800 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | The ORF of this clone is found to be a perfect match to NM_001964.2. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001964.2, NP_001955.1 |
| RefSeq Size | 3136 bp |
| RefSeq ORF | 1632 bp |
| Locus ID | 1958 |
| UniProt ID | P18146 |
| Domains | zf-C2H2 |
| Protein Families | Druggable Genome |
| Protein Pathways | Prion diseases |
| Gene Summary | The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppressor gene. [provided by RefSeq, Dec 2014] |
Citations (10)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Identification, Characterization, and Regulatory Mechanisms of a Novel EGR1 Splicing Isoform
,Aliperti, V;Sgueglia, G;Aniello, F;Vitale, E;Fucci, L;Donizetti, A;,
Int J Mol Sci
,PubMed ID 30925677
[EGR1]
|
|
EGR1 regulates cellular metabolism and survival in endocrine resistant breast cancer
,null,
Oncotarget
,PubMed ID 29228577
[EGR1]
|
|
A Novel Egr-1-Agrin Pathway and Potential Implications for Regulation of Synaptic Physiology and Homeostasis at the Neuromuscular Junction
,MacDonald, R;Barbat-Artigas, S;Cho, C;Peng, H;Shang, J;Moustaine, A;Carbonetto, S;Robitaille, R;Chalifour, LE;Paudel, H;,
Front Aging Neurosci
,PubMed ID 28824419
[EGR1]
|
|
EGR-1/Bax Pathway Plays a Role in Vitamin E d-Tocotrienol-induced Apoptosis in Pancreatic Cancer Cells
,Wang, C;Husain, K;Zhang, A;Centeno, BA;,
The Journal of Nutritional Biochemistry
[EGR1]
|
|
Regulation of Rad51 promoter
,null,
Cell Cycle
,PubMed ID 24781030
[EGR1]
|
|
EGR1 supports the osteogenic differentiation of dental stem cells
,Press, T;Viale-Bouroncle, S;Felthaus, O;Gosau, M;Morsczeck, C;,
Int Endod J. April 2014
,PubMed ID 24749562
[EGR1]
|
|
Identification of a Functional TPH1 Polymorphism Associated With Irritable Bowel Syndrome Bowel Habit Subtypes
,Grasberger, H;Chang, L;Shih, W;Presson, AP;Sayuk, GS;Newberry, RD;Karagiannides, I;Pothoulakis, C;Mayer, E;Merchant, JL;,
J. Pharmacol. Exp. Ther., Aug 2013; 346: 201 - 210.
,PubMed ID 24060757
[EGR1]
|
|
Cellular Immediate-Early Gene Expression Occurs Kinetically Upstream of Epstein-Barr Virus bzlf1 and brlf1 following Cross-Linking of the B Cell Antigen Receptor in the Akata Burkitt Lymphoma Cell Line
,Jianjiang Ye, Lyndle Gradoville, and George Miller,
J. Virol., Dec 2010; 84: 12405 - 12418
[EGR1]
|
|
Early Gene Expression is Kinetically Upstream of Epstein-Barr Virus bzlf1 and brlf1 Following Cross-linking of the B Cell Antigen Receptor in the Akata Burkitt Lymphoma Cell Line
,Jianjiang Ye, Lyndle Gradoville, and George Miller,
J. Virol., Sep 2010; 10.1128/JVI.01415-10
[EGR1]
|
|
EGR-1 activation by EGF inhibits MMP-9 expression and lymphoma growth
,Frédéric Bouchard, Simon D. Bélanger, Katherine Biron-Pain, and Yves St-Pierre,
Blood, Aug 2010; 116: 759 - 766
[EGR1]
|
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209956 | EGR1 (Myc-DDK-tagged)-Human early growth response 1 (EGR1) |
CNY 6,064.00 |
|
| RC209956L1 | Lenti ORF clone of Human early growth response 1 (EGR1), Myc-DDK-tagged |
CNY 8,464.00 |
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| RC209956L2 | Lenti ORF clone of Human early growth response 1 (EGR1), mGFP tagged |
CNY 8,464.00 |
|
| RC209956L3 | Lenti ORF clone of Human early growth response 1 (EGR1), Myc-DDK-tagged |
CNY 8,464.00 |
|
| RC209956L4 | Lenti ORF clone of Human early growth response 1 (EGR1), mGFP tagged |
CNY 8,464.00 |
|
| RG209956 | EGR1 (tGFP-tagged) - Human early growth response 1 (EGR1) |
CNY 7,664.00 |
