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Reticulocalbin 3 (RCN3) (NM_020650) Human Untagged Clone
CAT＃: SC128149
RCN3 (untagged)-Human reticulocalbin 3, EF-hand calcium binding domain (RCN3)
CNY 6,270.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | RLP49 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_020650, the custom clone sequence may differ by one or more nucleotides
ATGATGTGGCGACCATCAGTTCTGCTGCTTCTGTTGCTACTGAGGCACGGGGCCCAGGGGAAGCCATCCC CAGACGCAGGCCCTCATGGCCAGGGGAGGGTGCACCAGGCGGCCCCCCTGAGCGACGCTCCCCATGATGA CGCCCACGGGAACTTCCAGTACGACCATGAGGCTTTCCTGGGACGGGAAGTGGCCAAGGAATTCGACCAA CTCACCCCAGAGGAAAGCCAGGCCCGTCTGGGGCGGATCGTGGACCGCATGGACCGCGCGGGGGACGGCG ACGGCTGGGTGTCGCTGGCCGAGCTTCGCGCGTGGATCGCGCACACGCAGCAGCGGCACATACGGGACTC GGTGAGCGCGGCCTGGGACACGTACGACACGGACCGCGACGGGCGTGTGGGTTGGGAGGAGCTGCGCAAC GCCACCTATGGCCACTACGCGCCCGGTGAAGAATTTCATGACGTGGAGGATGCAGAGACCTACAAAAAGA TGCTGGCTCGGGACGAGCGGCGTTTCCGGGTGGCCGACCAGGATGGGGACTCGATGGCCACTCGAGAGGA GCTGACAGCCTTCCTGCACCCCGAGGAGTTCCCTCACATGCGGGACATCGTGATTGCTGAAACCCTGGAG GACCTGGACAGAAACAAAGATGGCTATGTCCAGGTGGAGGAGTACATCGCGGATCTGTACTCAGCCGAGC CTGGGGAGGAGGAGCCGGCGTGGGTGCAGACGGAGAGGCAGCAGTTCCGGGACTTCCGGGATCTGAACAA GGATGGGCACCTGGATGGGAGTGAGGTGGGCCACTGGGTGCTGCCCCCTGCCCAGGACCAGCCCCTGGTG GAAGCCAACCACCTGCTGCACGAGAGCGACACGGACAAGGATGGGCGGCTGAGCAAAGCGGAAATCCTGG GTAATTGGAACATGTTTGTGGGCAGTCAGGCCACCAACTATGGCGAGGACCTGACCCGGCACCACGATGA GCTGTGA >OriGene 5' read for NM_020650 unedited
CCCCGTTCAAAATTTGTATACGACTCATATAGGCGGCCTGCGAATCGGCACCAGGNAACG CAGAGCGGAGCGTGGAGAGCGGAGCGAAGCTGGATAACAGGGGACCGATGATGTGGCGAC CATCAGTTCTGCTGCTTCTGTTGCTACTGAGGCACGGGGCCCAGGGGAAGCCATCCCCAG ACGCAGGCCCTCATGGCCAGGGGAGGGTGCACCAGGCGGCCCCCCTGAGCGACGCTCCCC ATGATGACGCCCACGGGAACTTCCAGTACGACCATGAGGCTTTCCTGGGACGGGAAGTGG CCAAGGAATTCGACCAACTCACCCCAGAGGAAAGCCAGGCCCGTCTGGGGCGGATCGTGG ACCGCATGGACCGCGCGGGGGACGGCGACGGCTGGGTGTCGCTGGCCGAGCTTCGCGCGT GGATCGCGCACACGCAGCAGCGGCACATACGGGACTCGGTGAGCGCGGCCTGGGACACGT ACGACACGGACCGCGACGGGCGTGTGGGTTGGGAGGAGCTGCGCAACGCCACCTATGGCC ACTACGCGCCCGGTGAAGAATTTCATGACGTGGAGGATGCAGAGACCTACAAAAAGATGC TGGCTCGGGACGAGCGGCGTTTCCGGGTGGCCGCCAGGATGGGGACTCGATGGCCACTCG AGAGGAGCTGACAGCCTTCCTGCCCCCGNAGGAGTTCCCTCACATGCGGNGACATCGTGA TTGCTGACACCCTGNAGGACCTGGACAGAACCAAGAGGGCTTGTCCAGGTGGGAGGAGTA CATCGCGGACTGCGCCCCCACCCCCCCTGGGGGAGGAGAGCCGGCGTGGGTGCGACGGAG GGCCACCAATTCTGGCTTTTCCGGATCTGACCACGATGGCACTGATTGNGAAAGTNAGGA GCCCTCTTGGGTGCTGCCCCTG >OriGene 3' read for NM_020650 unedited
NTTTCGTGCGGCTTTTATGCCTCTGGCANGAGGNAGTGTCCCCGGCCAGGCCAGGCAGGA GAGGGCTGGGGCCAGGGGAGTTTCAGTCTATGTGGTGGAGGCTCAGATTTGGAGCTGGAG GGGTTGGGGCGGTTCTTAGAGCTGAGCTTGGGGCCAAGGGTCCCTGGGTCTGGGCTGGGA GACTCAGTCAGAAATAGGTATTGCTTATCCTCTGGGACTATGACAGCCCCTCCCTGGGGT TGGGGGTGTGACAGGGACAGAAGCCGACCCAGGGGGTCCCTGACAGCCCAGGGGCAGGAG GATGCCTGGGACTGCATCTGCCTCCTGCGGGGCCTGGACAGGGAGGGGGCCAGACCACAG CGGCCCCTCCTCAGGTCATTGTGCGGCCCTCTGAGGCTGTGGCACGTGCGCGGTGCTCAC AGCTCATCGCGCTGCCGGGTCAGGTCCTCGCCATAGTTGGTGGCCTGACTGCCCACAAAC GTGGTCCAGTTACGCCAGATTTCCGCTTTGCTTAGCCGCCAATCCTTGTCCGTGTCCGCT CCGTGCACCGGGTGGGTGGCTCCCACGAAGGGCTGGGCTTGGTCAGGGGGCAGGACTCAG TGGTTCACCTTACTCCCATCCAGGTGCCTATCTTTGTTCCAATCCCGGGAATCTCGTAGT TGCTGTCCCGTCGGTTGCGGGCATGCTGGCTCTTCGTCCGCAGGCTCGCTTGATTCTACT TCCGAGGTGGTGCTCGTCAACCGGTCCTTAACGTTCTTCTCTCTCGGGCACGGACCCTAG TGTTTTATCGACCACTACCTTCAGGTTTGTAGCGCGAACCCTTCCGCCGTGAGGGAAGGC ATCCCCCTCCTCTCCAGAGAGGTTTATAATCCCCTTCCGGGGGGCCCTACCGGACAACCC GTGTTGCCCCG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_020650 |
| Insert Size | 1650 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_020650.2, NP_065701.2 |
| RefSeq Size | 1882 bp |
| RefSeq ORF | 987 bp |
| Locus ID | 57333 |
| UniProt ID | Q96D15 |
| Domains | EFh |
| Gene Summary | Probable molecular chaperone assisting protein biosynthesis and transport in the endoplasmic reticulum (PubMed:16433634, PubMed:28939891). Required for the proper biosynthesis and transport of pulmonary surfactant-associated protein A/SP-A, pulmonary surfactant-associated protein D/SP-D and the lipid transporter ABCA3 (By similarity). By regulating both the proper expression and the degradation through the endoplasmic reticulum-associated protein degradation pathway of these proteins plays a crucial role in pulmonary surfactant homeostasis (By similarity). Has an anti-fibrotic activity by negatively regulating the secretion of type I and type III collagens (PubMed:28939891). This calcium-binding protein also transiently associates with immature PCSK6 and regulates its secretion (PubMed:16433634).[UniProtKB/Swiss-Prot Function] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203708 | RCN3 (Myc-DDK-tagged)-Human reticulocalbin 3, EF-hand calcium binding domain (RCN3) |
CNY 2,400.00 |
|
| RC203708L3 | Lenti ORF clone of Human reticulocalbin 3, EF-hand calcium binding domain (RCN3), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC203708L4 | Lenti ORF clone of Human reticulocalbin 3, EF-hand calcium binding domain (RCN3), mGFP tagged |
CNY 5,890.00 |
|
| RG203708 | RCN3 (tGFP-tagged) - Human reticulocalbin 3, EF-hand calcium binding domain (RCN3) |
CNY 4,000.00 |
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