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SCN7A (NM_002976) Human Untagged Clone
CAT＃: SC128285
SCN7A (untagged)-Human sodium channel, voltage-gated, type VII, alpha (SCN7A)
CNY 16,968.00
货期*
现货
规格
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | NaG; Nav2.1; Nav2.2; SCN6A |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_002976 edited
AGAAAACCCGAGAGATCCGTGGAGAAAGAGAAGCCCAGGAGGAGGAAAAGGCTCCAAGGA GCCCTAGCTCCTGAAGGGTCCCTCAGGCACTGGTGGAGACCTGTCGCTTCGTAGCAAGTA CAAAATTGGAAATGTTGGCTTCACCAGAACCTAAGGGCCTTGTTCCCTTCACTAAAGAGT CTTTTGAACTTATAAAACAGCATATTGCTAAAACACATAATGAAGACCATGAAGAAGAAG ACTTAAAGCCAAATCCTGATTTGGAAGTTGGCAAAAAGCTTCCATTTATTTATGGAAACC TTTCTCAAGGAATGGTGTCAGAGCCCTTGGAAGATGTGGACCCATATTACTACAAGAAAA AAAATACTTTCATAGTATTAAATAAAAATAGAACAATCTTCAGATTCAATGCGGCTTCCA TCTTGTGTACATTGTCTCCTTTCAATTGTATTAGAAGAACAACTATCAAGGTTTTGGTAC ATCCCTTTTTCCAACTGTTTATTCTAATTAGTGTCCTGATTGATTGCGTATTCATGTCCC TGACTAATTTGCCAAAATGGAGACCAGTATTAGAGAATACTTTGCTTGGAATTTACACAT TTGAAATACTTGTAAAACTCTTTGCAAGAGGTGTCTGGGCAGGATCATTTTCCTTCCTCG GTGATCCATGGAACTGGCTCGATTTCAGCGTAACTGTGTTTGAGGTTATTATAAGATACT CACCTCTGGACTTCATTCCAACGCTTCAAACTGCAAGAACTTTGAGAATTTTAAAAATTA TTCCTTTAAATCAAGGTCTGAAATCCCTTGTAGGGGTCCTGATCCACTGCTTGAAGCAGC TTATTGGTGTCATTATCCTAACTCTGTTTTTTCTGAGCATATTTTCTCTAATTGGGATGG GGCTCTTCATGGGCAACTTGAAACATAAATGTTTTCGATGGCCCCAAGAGAATGAAAATG AAACCCTGCACAACAGAACTGGAAACCCATATTATATTCGAGAAACAGAAAACTTTTATT ATTTGGAAGGAGAAAGATATGCTCTCCTTTGTGGCAACAGGACAGATGCTGGTCAGTGTC CTGAAGGATATGTGTGTGTAAAAGCTGGCATAAATCCTGATCAAGGCTTCACAAATTTTG ACAGTTTTGGCTGGGCCTTATTTGCCCTATTTCGGTTAATGGCTCAGGATTACCCTGAAG TACTTTATCACCAGATACTTTATGCTTCTGGGAAGGTCTACATGATATTTTTTGTGGTGG TAAGTTTTTTGTTTTCCTTTTATATGGCAAGTTTGTTCTTAGGCATACTTGCCATGGCCT ATGAAGAAGAAAAGCAGAGAGTTGGTGAAATATCTAAGAAGATTGAACCAAAATTTCAAC AGACTGGAAAAGAACTTCAAGAAGGAAATGAAACAGATGAGGCCAAGACCATACAAATAG AAATGAAGAAAAGGTCACCAATTTCCACAGACACATCATTGGATGTGTTGGAAGATGCTA CTCTCAGACATAAGGAAGAACTTGAAAAATCCAAGAAGATATGCCCATTATACTGGTATA AGTTTGCTAAAACTTTCTTGATCTGGAATTGTTCTCCCTGTTGGTTAAAATTGAAAGAGT TTGTCCATAGGATTATAATGGCACCATTTACTGATCTTTTCCTTATCATATGCATAATTT TAAACGTATGTTTTCTGACCTTGGAGCATTATCCAATGAGTAAACAAACTAACACTCTTC TCAACATTGGAAACCTGGTTTTCATTGGAATTTTCACAGCAGAAATGATTTTTAAAATAA TTGCAATGCATCCATATGGGTATTTCCAAGTAGGTTGGAACATTTTTGATAGCATGATAG TGTTCCATGGTTTAATAGAACTTTGTCTAGCAAATGTTGCAGGAATGGCTCTTCTTCGAT TATTCAGGATGTTAAGAATTTTCAAGTTGGGAAAGTATTGGCCAACATTCCAGATTTTGA TGTGGTCTCTTAGTAACTCATGGGTGGCCCTGAAAGACTTGGTCCTGTTGTTGTTCACAT TCATCTTCTTTTCTGCTGCATTCGGCATGAAGCTGTTTGGTAAGAATTATGAAGAATTTG TCTGCCACATAGACAAAGACTGTCAACTCCCACGCTGGCACATGCATGACTTTTTCCACT CCTTCCTGAATGTGTTCCGAATTCTCTGTGGAGAGTGGGTAGAGACCTTGTGGGACTGTA TGGAGGTTGCAGGCCAATCCTGGTGTATTCCTTTTTACCTGATGGTCATTTTAATTGGAA ATTTACTGGTACTTTACCTGTTTCTGGCATTGGTGAGCTCATTTAGTTCATGCAAGGATG TAACAGCTGAAGAGAATAATGAAGCAAAAAATCTCCAGCTTGCAGTGGCAAGAATTAAAA AAGGAATAAACTATGTGCTTCTTAAAATACTATGCAAAACACAAAATGTCCCAAAGGACA CAATGGACCATGTAAATGAGGTATATGTTAAAGAAGATATTTCTGACCATACCCTTTCTG AATTGAGCAACACCCAAGATTTTCTCAAAGATAAGGAAAAAAGCAGTGGCACAGAGAAAA ACGCTACTGAAAATGAGAGCCAATCACTTATCCCCAGTCCTAGTGTCTCAGAAACTGTAC CAATTGCTTCAGGAGAATCTGATATAGAAAATCTGGATAATAAGGAGATTCAGAGTAAGT CTGGTGATGGAGGCAGCAAAGAGAAAATAAAGCAATCTAGCTCATCTGAATGCAGTACTG TTGATATTGCTATCTCTGAAGAAGAAGAAATGTTCTATGGAGGTGAAAGATCAAAGCATC TGAAAAATGGTTGCAGACGCGGATCTTCACTTGGTCAAATCAGTGGAGCATCCAAGAAAG GAAAAATCTGGCAGAACATCAGGAAAACCTGCTGCAAGATTGTAGAGAACAATTGGTTTA AGTGTTTTATTGGGCTTGTTACTCTGCTCAGCACTGGCACTCTGGCTTTTGAAGATATAT ATATTGATCAGAGAAAGACAATTAAAATTTTATTAGAATATGCTGACATGATCTTTACTT ATATCTTCATTCTGGAAATGCTTCTAAAATGGATGGCATATGGTTTTAAGGCCTATTTCT CTAATGGCTGGTACAGGCTGGACTTCGTGGTTGTTATTGTGTTTTGTCTTAGCTTAATAG GCAAAACTCGGGAAGAACTAAAACCTCTTATTTCCATGAAATTCCTTCGGCCCCTCAGAG TTCTATCTCAATTTGAAAGAATGAAGGTGGTTGTGAGAGCTTTGATCAAAACAACCTTAC CCACTTTGAATGTGTTTCTTGTCTGCCTGATGATCTGGCTGATTTTTAGTATCATGGGAG TAGACTTATTTGCTGGCAGATTCTATGAATGCATTGACCCAACAAGTGGAGAAAGGTTTC CTTCATCTGAAGTCATGAATAAGAGTCGGTGTGAAAGCCTTCTGTTTAACGAATCCATGC TATGGGAAAATGCAAAAATGAACTTTGATAATGTTGGAAATGGTTTCCTTTCTCTGCTTC AAGTAGCAACATTTAATGGATGGATCACTATTATGAATTCAGCAATTGATTCTGTTGCTG TTAATATACAGCCTCATTTTGAAGTCAACATCTACATGTATTGTTACTTTATCAACTTTA TTATATTTGGAGTATTTCTCCCTCTGAGTATGCTGATTACTGTTATTATTGATAATTTCA ACAAGCATAAAATAAAGCTGGGAGGCTCAAATATCTTTATAACGGTTAAACAGAGAAAAC AGTACCGCAGGCTGAAGAAGCTAATGTATGAGGATTCTCAAAGACCAGTACCTCGCCCAT TAAACAAGCTCCAAGGATTCATCTTTGATGTGGTAACAAGCCAAGCTTTTAATGTCATTG TTATGGTTCTTATATGTTTCCAAGCAATAGCCATGATGATAGACACTGATGTTCAGAGTC TACAAATGTCCATTGCTCTCTACTGGATTAACTCAATTTTTGTTATGCTATATACTATGG AATGTATACTGAAGCTCATCGCTTTCCGTTGTTTTTATTTCACCATTGCGTGGAACATTT TTGATTTTATGGTGGTTATTTTCTCCATCACAGGACTATGTCTGCCTATGACAGTAGGAT CCTACCTTGTGCCTCCTTCACTTGTGCAACTGATACTTCTCTCACGGATCATTCACATGC TGCGTCTTGGAAAAGGACCAAAGGTGTTTCATAATCTGATGCTTCCTTTGATGCTGTCCC TCCCAGCATTATTGAACATCATTCTTCTCATCTTCCTGGTCATGTTCATCTATGCCGTAT TTGGAATGTATAATTTTGCCTATGTTAAAAAAGAAGCTGGAATTAATGATGTGTCTAATT TTGAAACCTTTGGCAACAGTATGCTCTGTCTTTTTCAAGTTGCAATATTTGCTGGTTGGG ATGGGATGCTTGATGCAATTTTCAACAGTAAATGGTCTGACTGTGATCCTGATAAAATTA ACCCTGGGACTCAAGTTAGAGGAGATTGTGGGAACCCCTCTGTTGGGATTTTTTATTTTG TCAGTTATATCCTCATATCATGGCTGATCATTGTAAATATGTACATTGTTGTTGTCATGG AGTTTTTAAATATTGCTTCTAAGAAGAAAAACAAGACCTTGAGTGAAGATGATTTTAGGA AATTCTTTCAGGTATGGAAAAGGTTTGATCCTGATAGGACCCAGTACATAGACTCTAGCA AGCTTTCAGATTTTGCAGCTGCTCTTGATCCTCCTCTTTTCATGGCAAAACCAAACAAGG GCCAGCTCATTGCTTTGGACCTCCCCATGGCTGTTGGGGACAGAATTCATTGCCTCGATA TCTTACTTGCTTTTACAAAGAGAGTTATGGGTCAAGATGTGAGGATGGAGAAAGTTGTTT CAGAAATAGAATCAGGGTTTTTGTTAGCCAACCCTTTTAAGATCACATGTGAGCCAATTA CGACTACTTTGAAACGAAAACAAGAGGCAGTTTCAGCAACCATCATTCAACGTGCTTATA AAAATTACCGCTTGAGGCGAAATGACAAAAATACATCAGATATTCATATGATAGATGGTG ACAGAGATGTTCATGCTACTAAAGAAGGTGCCTATTTTGACAAAGCTAAGGAAAAGTCAC CTATTCAAAGCCAGATCTAATACCACTTACCACCTCTTTTCATATTTCTTCACATATCTG AAAAATGTTGAAAGCCTAAGCCAGGAATAAAAGAAAAGTAGAGATAATAATCAGTTCTTT ACAACCGATGGTAATTAAGCTTGTATTCACAAGACTTCATGCCAAATTCACTTTTTAGCA TTATATCTAACAAATCAAGAGAATCCTTAATATTGCTGCAGTGAGTTTAAAGTGGGTTAA AGTGGCCATTTGACAATCTCATATTTGTTTTCTCTACATGGCTTATATGATGTGTGCCTT CTAGGGAATGAAGGGAAGTGGTGATAGAGATCAGCAGCAGCAGGGGCTTTCTTTTATATT TTATGTATAATTTAATGGGCTTTAAGTCACCACTATTAAGACTTACAAATAAGCAAATAC TTTCCTGATGTGGGATGGTGAAATGCTAATGGCCATTAAATCATAAACTTGCCTAGACAA AAGCCAATTGGAAGAAGGGAGAGAGCAGTTCTTTAGAAAGTGCCTTTGAGATCAACCTCA GAGATTCTTGGGCTGATTAAAACTGCATTTGAAAAAGATTGGTTGAAGCTCTGTGTTTAT TTTTGTATGTTCTTGTTTTCATTTGGAACTGGGAATGAATAGGATTTCATTGTGCTCAAG CTCCTGGTTTCTCATCTCTGGATAGTTTCACCTAAGCTCTGGCTCTTAAGCAGGACAGAT TCGTAAAACAAGAAGCATAAAGGAGAGGTATAGCCTTTTTTTTTTTTTTTTTTCATTTTC TTCTCATTTACACCTATTTTTTTAAAAAGTATACATTTACTAAAATGATGTAATAAATAA CATGTTAATAGACTCAAGCTTTACCTTATGAAATTGATGTATTTTTACCAGTTATTTCTA ATGTAACATTGAATATATAAGATCTGACAAATGTATGTTTAAACATGAGTTAGAAGAGTT GAGAACTACCATTATGTATAGGGATTCTCATAGTGTCTTGGCCCTTAATTGGAAAGTTGT GGCAACTTTAAAGTACTTTTTACTGTATGTTATAATTCTTTATAACTTAGAGAGAGACAA TGGTCACTCAAACTATGAGAACTATGAATTAGGAGATAAAAGTTTAAATTTGTTGTTGTT TTATAACAGTATGTACAAGTTAGTTTTCCCTTATATATTTACGTTTTTCAGTTTTTTAAT TTCATCATATACATCCATACTCTATAAAATGTTTTATATTCAAAGAACTGTAAAATCCTA AACATTAGTTTTCACTATTGAAATTGTTTTTTAAAGATAGGCATAAATAGTTGTCCTTAG ACTTATTCATACAAATATAGTCATTTACTTCTATGTAGTTTGAGATTCTGAGAGTTATTC CAACTTTATGAAGATTGATTTCAATGTGCCTGCTAAGTCCTAAAAGATTCAGAAAGAAAA TTTATATATTATTGATTTAAATGTCATCCTTTAAATATGTTGTATAACATTCAATATAGT TTATGTATCAGTGATTGTATTTTATTCTGAATGCATGATCTCAAGCCTTAACTACTATAA TCTTTTTCTGCCCCTCAGAAATTGAATAACCTAACCAAGATGCCTTTAGGGGATGCCCTA AGTAAATGTAATTTCAGATTTCAGGGTTTTTTTTTTTTCCTCTCTAAGTGTTCCTTCCCT TTCTTCTCATGCTCTCCATCATGTTATGGAGACCAGTGAGGAACCAGTGTTAACTTGGTG ACAATGTGACAGCTGGTGCTTTATCTAAGCTCCGTTTTCTATTTCTTGGGAATGCTTTAT TGTGGAAACTGCTTCAGATACTTAAATTGAATCATAACTTGCTTCTGTAAATTGCGTAAA GACAACAAACTGATTTTAGTTTGAAAAGTTTATCTTTTACTTGTAAACCTTGTTTGCCAG TTACCTTCCGAAAGCTGTGTAAAGAGTTATTTTTAACAAAGTCTTAACAATATATGTTAC TTTTTAGATACTATAGAAAATAATAAATATAACCTGTAAACCAAAAAAGAG >OriGene 5' read for NM_002976 unedited
ACCGTCCGTTGCGCAAAGGGCGGTAGGCGTGTACTGTTGGGAGGTCTATATAAGCAGAGC TCAGAAAACCCGAGAGATCCGTGGAGAAAGAGAAGCCCAGGAGGAGGAAAAAGGCTCCAA GGAGCCCTAGCTCCTGAAGGGTCCCTCAGGCACTGGTGGAGACCTGTCGCTTCGTAGCAA GTACAAAATTGGAAATGTTGGCTTCACCAGAACCTAAGGGCCTTGTTCCCTTCACTAAAG AGTCTTTTGAACTTATAAAACAGCATATTGCTAAAACACATAATGAAGACCATGAAGAAG AAGACTTAAAGCCAAATCCTGATTTGGAAGTTGGCAAAAAGCTTCCATTTATTTATGGAA ACCTTTCTCAAGGAATGGTGTCAGAGCCCTTGGAAGATGTGGACCCATATTACTACAAGA AAAAAAATACTTTCATAGTATTAAATAAAAATAGAACAATCTTCAGATTCAATGCGGCTT CCATCTTGTGTACATTGTCTCCTTTCAATTGTATTAGAAGAACAACTATCAAGGTTTTGG TACATCCCTTTTTCCAACTGTTTATTCTAATTAGTGTCCTGATTGATTGCGTATTCATGT CCCTGACTAATTTGCCAAAATGGAGACCAGTATTAGAGAATACTTTGCTTGGAATTTACA CATTTGAAATACTTGTAAAAACTCTTTGCAAGAGGTGTCTGGGCAGGATCATTTTCCTTC CTCGGTGATCCATGGAACTGGCTCGATTTCAGCGTAACTGTGTTTGAGGTTATTATAAGA TACTCACCTCTGGACTTCATTCCAACGCTTCAAACTGCAAGAACTTTGAGAATTTTAAAA ATTATTCCTTTAAATCAAGTCTGAATCCCTTGTAGGGTCTGATCACTGCTGAGCAGCTAT GTGTCATTATCCTAACTCTTGTTTTTTCTGGAGCATATTTTCTTCTAT >Forward primer walk for NM_002976 unedited
TCCGTATTTGGACTGTATAATTTTGCCTATTGTTAAAAAAGAAGCCTGGAATTAATGATG TGTCTAATTTTGAAACCTTTGGCAACAGTATGCTCTGTCTTTTTCAAGTTGCAATATTTG CTGGTTGGGATGGGATGCTTGATGCAATTTTCAACAGTAAATGGTCTGACTGTGATCCTG ATAAAATTAACCCTGGGACTCAAGTTAGAGGAGATTGTGGGAACCCCTCTGTTGGGATTT TTTATTTTGTCAGTTATATCCTCATATCATGGCTGATCATTGTAAATATGTACATTGTTG TTGTCATGGAGTTTTTAAATATTGCTTCTAAGAAGAAAAACAAGACCTTGAGTGAAGATG ATTTTAGGAAATTCTTTCAGGTATGGAAAAGGTTTGATCCTGATAGGACCCAGTACATAG ACTCTAGCAAGCTTTCAGATTTTGCAGCTGCTCTTGATCCTCCTCTTTTCATGGCAAAAC CAAACAAGGGCCAGCTCATTGCTTTGGACCTCCCCATGGCTGTTGGGGACAGAATTCATT GCCTCGATATCTTACTTGCTTTTACAAAGAGAGTTATGGGTCAAGATGTGAGGATGGAGA AAGTTGTTTCAGAAATAGAATCAGGGTTTTTGTTAGCCAACCCTTTTAAGATCACATGTG AGCCAATTACGACTACTTTGAAACGAAAACAAGAGGCAGTTTCAGCAACCATCATTCAAC GTGCTTATAAAAATTACCGCTTGAGGCGAAATGACAAAAATACATCAGATATTCATATGA TAGATGGTGACAGAGATGTTCATGCTACTAAAGAAGTGCCTATTTTGACAAAGCTAAGGA AAAGTCACCTATTCAAAGCCAGATCTATACCACTTACCACCTCTTTCATATTTCTCACAT ATCTGAAAAATGTGAAAGCCTAGCAGGAATAAAAGAAAAGTAGAGATAATAATCAGT |
| Restriction Sites | Please inquire |
| ACCN | NM_002976 |
| Insert Size | 7200 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_002976.2, NP_002967.2 |
| RefSeq Size | 5727 bp |
| RefSeq ORF | 5049 bp |
| Locus ID | 6332 |
| UniProt ID | Q01118 |
| Protein Families | Druggable Genome, Ion Channels: Other, Transmembrane |
| Gene Summary | This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown. [provided by RefSeq, Dec 2011] Transcript Variant: This variant (1) is the protein-coding transcript. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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