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Frizzled 7 (FZD7) (NM_003507) Human Untagged Clone
CAT＃: SC303322
FZD7 (untagged)-Human frizzled family receptor 7 (FZD7)
CNY 6,424.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | FzE3 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_003507 edited
ACTCGCGGCCGGCGATGCGGGACCCCGGCGCGGCCGCTCCGCTTTCGTCCCTGGGCCTCT GTGCCCTGGTGCTGGCGCTGCTGGGCGCACTGTCCGCGGGCGCCGGGGCGCAGCCGTACC ACGGAGAGAAGGGCATCTCCGTGCCGGACCACGGCTTCTGCCAGCCCATCTCCATCCCGC TGTGCACGGACATCGCCTACAACCAGACCATCCTGCCCAACCTGCTGGGCCACACGAACC AAGAGGACGCGGGCCTCGAGGTGCACCAGTTCTACCCGCTGGTGAAGGTGCAGTGTTCTC CCGAACTCCGCTTTTTCTTATGCTCCATGTATGCGCCCGTGTGCACCGTGCTCGATCAGG CCATCCCGCCGTGTCGTTCTCTGTGCGAGCGCGCCCGCCAGGGCTGCGAGGCGCTCATGA ACAAGTTCGGCTTCCAGTGGCCCGAGCGGCTGCGCTGCGAGAACTTCCCGGTGCACGGTG CGGGCGAGATCTGCGTGGGCCAGAACACGTCGGACGGCTCCGGGGGCCCAGGCGGCGGCC CCACTGCCTACCCTACCGCGCCCTACCTGCCGGACCTGCCCTTCACCGCGCTGCCCCCGG GGGCCTCAGATGGCAGGGGGCGTCCCGCCTTCCCCTTCTCATGCCCCCGTCAGCTCAAGG TGCCCCCGTACCTGGGCTACCGCTTCCTGGGTGAGCGCGATTGTGGCGCCCCGTGCGAAC CGGGCCGTGCCAACGGCCTGATGTACTTTAAGGAGGAGGAGAGGCGCTTCGCCCGCCTCT GGGTGGGCGTGTGGTCCGTGCTGTGCTGCGCCTCGACGCTCTTTACCGTTCTCACCTACC TGGTGGACATGCGGCGCTTCAGCTACCCAGAGCGGCCCATCATCTTCCTGTCGGGCTGCT ACTTCATGGTGGCCGTGGCGCACGTGGCCGGCTTCCTTCTAGAGGACCGCGCCGTGTGCG TGGAGCGCTTCTCGGACGATGGCTACCGCACGGTGGCGCAGGGCACCAAGAAGGAGGGCT GCACCATCCTCTTCATGGTGCTCTACTTCTTCGGCATGGCCAGCTCCATCTGGTGGGTCA TTCTGTCTCTCACTTGGTTCCTGGCGGCCGGCATGAAGTGGGGCCACGAGGCCATCGAGG CCAACTCGCAGTACTTCCACCTGGCCGCGTGGGCCGTGCCCGCCGTCAAGACCATCACTA TCCTGGCCATGGGCCAGGTAGACGGGGACCTGCTGAGCGGGGTGTGCTACGTTGGCCTCT CCAGTGTGGACGCGCTGCGGGGCTTCGTGCTGGCGCCTCTGTTCGTCTACCTCTTCATAG GCACGTCCTTCTTGCTGGCCGGCTTCGTGTCCCTCTTCCGTATCCGCACCATCATGAAAC ACGACGGCACCAAGACCGAGAAGCTGGAGAAGCTCATGGTGCGCATCGGCGTCTTCAGCG TGCTCTACACAGTGCCCGCCACCATCGTCCTGGCCTGCTACTTCTACGAGCAGGCCTTCC GCGAGCACTGGGAGCGCACCTGGCTCCTGCAGACGTGCAAGAGCTATGCCGTGCCCTGCC CGCCCGGCCACTTCCCGCCCATGAGCCCCGACTTCACCGTCTTCATGATCAAGTACCTGA TGACCATGATCGTCGGCATCACCACTGGCTTCTGGATCTGGTCGGGCAAGACCCTGCAGT CGTGGCGCCGCTTCTACCACAGACTTAGCCACAGCAGCAAGGGGGAGACTGCGGTATGAG CCCCGGCCCCTCCCCACCTTTCCCACCCCAGCCCTCTTGCAAGAGGAGAGGCACGGTAGG GAAAAGAACTGCTGGGTGGGGGCCTGTTTCTGTAACTTTCTCCCCCTCTACTGAGAAGTG ACCTGGAAGTGAGAAGTTTTTTGCAGATTTGGGGCGAGGGGTGATTTGGAAAAGAAGACC TGTGTGGAAAGCGGTTTGGATGAAAAGATTTCAGGCAAAGACTTGCAGGAAGATGATGAT AACGGCGATGTGAATCGTCAAAGGTACGGGCCAGCTTGTGCCTAATAGAAGGTTGAGACC AGCAGAGACTGCTGTGAGTTTCTCCCGGCTCCGAGGCTGAACGGGGACTGTGAGCGATCC CCCTGCTGCAGGGCGAGTGGCCTGTCCAGACCCCTGTGAGGCCCCGGGAAAGGTACAGCC CTGTCTGCGGTGGCTGCTTTGTTGGAAAGAGGGAGGGCCTCCTGCGGTGTGCTTGTCAAG CAGTGGTCAAACCATAATCTCTTTTCACTGGGGCCAAACTGGAGCCCAGATGGGTTAATT TCCAGGGTCAGACATTACGGTCTCTCCTCCCCTGCCCCCTCCCGCCTGTTTTTCCTCCCG TACTGCTTTCAGGTCTTGTAAAATAAGCATTTGGAAGTCTTGGGAGGCCTGCCTGCTAGA ATCCTAATGTGAGGATGCAAAAGAAATGATGATAACATTTTGAGATAAGGCCAAGGAGAC GTGGAGTAGGTATTTTTGCTACTTTTTCATTTTCTGGGGAAGGCAGGAGGCAGAAAGACG GGTGTTTTATTTGGTCTAATACCCTGAAAAGAAGTGATGACTTGTTGCTTTTCAAAACAG GAATGCATTTTTCCCCTTGTCTTTGTTGTAAGAGACAAAAGAGGAAACAAAAGTGTCTCC CTGTGGAAAGGCATAACTGTGACGAAAGCAACTTTTATAGGCAAAGCAGCGCAAATCTGA GGTTTCCCGTTGGTTGTTAATTTGGTTGAGATAAACATTCCTTTTTAAGGAAAAGTGAAG AGCAGTGTGCTGTCACACACCGTTAAGCCAGAGGTTCTGACTTCGCTAAAGGAAATGTAA GAGGTTTTGTTGTCTGTTTTAAATAAATTTAATTCGGAACACATGATCCAACAGACTATG TTAAAATATTCAGGGAAATCTCTCCCTTCATTTACTTTTTCTTGCTATAAGCCTATATTT AGGTTTCTTTTCTATTTTTTTCTCCCATTTGGATCCTTTGAGGTAAAAAAACATAATGTC TTCAGCCTCATAATAAAGGAAAGTTAATTAAAAAAAAAAAGCAAAGAAAAAAAAAAAAAA AAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_003507 |
| Insert Size | 3100 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003507.1, NP_003498.1 |
| RefSeq Size | 3851 bp |
| RefSeq ORF | 1725 bp |
| Locus ID | 8324 |
| UniProt ID | O75084 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Basal cell carcinoma, Colorectal cancer, Melanogenesis, Pathways in cancer, Wnt signaling pathway |
| Gene Summary | Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6
,ME Binnerts, KA Kim, JM Bright, SM Patel, K Tran, M Zhou, JM Leung, Y Liu, WE Lomas 3rd, M Dixon, SA Hazell, M Wagle, WS Nie, N Tomasevic, J Williams, X Zhan, MD Levy, WD Funk, and A Abo,
Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14700-5.
[FZD7]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204167 | FZD7 (Myc-DDK-tagged)-Human frizzled family receptor 7 (FZD7) |
CNY 6,408.00 |
|
| RC204167L1 | Lenti ORF clone of Human frizzled family receptor 7 (FZD7), Myc-DDK-tagged |
CNY 8,808.00 |
|
| RC204167L2 | Lenti ORF clone of Human frizzled family receptor 7 (FZD7), mGFP tagged |
CNY 8,808.00 |
|
| RC204167L3 | Lenti ORF clone of Human frizzled family receptor 7 (FZD7), Myc-DDK-tagged |
CNY 8,808.00 |
|
| RC204167L4 | Lenti ORF clone of Human frizzled family receptor 7 (FZD7), mGFP tagged |
CNY 8,808.00 |
|
| RG204167 | FZD7 (tGFP-tagged) - Human frizzled family receptor 7 (FZD7) |
CNY 8,008.00 |
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