SCARF2 (NM_182895) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	NSR1; SREC-II; SREC2; SRECRP-1; VDEGS
Vector	pCMV6 series
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for NM_182895, the custom clone sequence may differ by one or more nucleotides ATGGAGGGCGCAGGGCCCCGGGGGGCCGGGCCGGCGCGGCGCCGGGGAGCCGGGGGGCCG CCGTCACCGCTGCTGCCGTCGCTGCTGCTGCTGCTGCTGCTCTGGATGCTGCCGGACACC GTGGCGCCTCAGGAACTGAACCCTCGCGGCCGCAACGTGTGCCGTGCTCCCGGCTCCCAG GTGCCCACGTGCTGCGCTGGCTGGAGGCAGCAAGGGGACGAGTGTGGGATTGCGGTGTGC GAAGGCAACTCCACGTGCTCAGAGAACGAGGTGTGCGTGAGGCCTGGCGAGTGCCGCTGC CGCCACGGCTACTTCGGTGCCAACTGCGACACCAAGTGCCCGCGCCAGTTCTGGGGCCCC GACTGCAAGGAGCTGTGTAGCTGCCACCCACACGGGCAGTGCGAGGACGTGACAGGCCAG TGTACTTGTCACGCGCGGCGCTGGGGCGCGCGCTGCGAGCATGCGTGCCAGTGCCAGCAC GGCACGTGCCACCCGCGGAGCGGCGCGTGCCGCTGTGAGCCCGGCTGGTGGGGCGCGCAG TGCGCCAGCGCGTGCTACTGCAGCGCCACGTCGCGCTGCGACCCACAGACCGGCGCCTGC CTGTGCCACGCAGGCTGGTGGGGCCGCAGCTGCAACAACCAGTGCGCCTGCAACTCGTCT CCCTGCGAGCAGCAGAGCGGCCGCTGTCAGTGCCGCGAGCGTACGTTCGGCGCGCGCTGC GATCGCTACTGCCAGTGCTTCCGCGGCCGCTGCCACCCTGTGGACGGCACGTGTGCCTGC GAGCCGGGCTACCGCGGCAAGTACTGTCGCGAGCCGTGCCCCGCCGGCTTCTACGGCTTG GGCTGTCGCCGCCGGTGTGGCCAGTGCAAGGGCCAGCAGCCGTGCACGGTGGCCGAGGGC CGCTGCTTGACGTGCGAGCCCGGCTGGAACGGAACCAAGTGCGACCAGCCTTGCGCCACC GGTTTCTATGGCGAGGGCTGCAGCCACCGCTGTCCGCCATGCCGCGACGGGCATGCCTGT AACCATGTCACCGGCAAGTGTACGCGCTGCAACGCGGGCTGGATCGGCGACCGGTGCGAG ACCAAGTGTAGCAATGGCACTTACGGCGAGGACTGCGCCTTCGTGTGCGCCGACTGCGGC AGCGGACACTGCGACTTCCAGTCGGGGCGCTGCCTGTGCAGCCCTGGCGTCCACGGGCCC CACTGTAACGTGACGTGCCCGCCCGGACTCCACGGCGCGGACTGTGCTCAGGCCTGCAGC TGCCACGAGGACACGTGCGACCCGGTCACTGGTGCCTGCCACCTAGAAACCAACCAGCGC AAGGGCGTGATGGGCGCGGGCGCGCTGCTCGTCCTGCTCGTCTGCCTGCTGCTCTCGCTG CTCGGCTGCTGCTGCGCTTGCCGCGGCAAGGACCCTACGCGCCGGGAGCTTTCGCTTGGG AGGAAGAAGGCGCCGCACCGACTATGCGGGCGCTTCAGTCGCATCAGCATGAAGCTGCCC CGGATCCCGCTCCGGAGGCAGAAACTACCCAAAGTCGTAGTGGCCCACCACGACCTGGAT AACACACTCAACTGCAGCTTCCTGGAGCCACCCTCAGGGCTGGAGCAGCCCTCACCATCC TGGTCCTCTCGGGCCTCCTTCTCCTCGTTTGACACCACTGATGAAGGCCCTGTGTACTGT GTACCCCATGAGGAGGCACCAGCGGAGAGCCGGGACCCCGAAGTCCCCACTGTCCCTGCC GAGGCGCCGGCGCCGTCCCCTGTGCCCTTGACCACGCCAGCCTCCGCCGAGGAGGCGATA CCCCTCCCCGCGTCCTCCGACAGCGAGCGGTCGGCGTCCAGCGTGGAGGGGCCCGGAGGG GCTCTGTACGCGCGCGTGGCCCGACGCGAGGCCCGGCCGGCCCGGGCCCGGGGCGAGATT GGGGGCCTGTCGCTGTCGCCATCGCCCGAGCGCAGGAAACCGCCGCCACCTGACCCCGCC ACCAAGCCTAAGGTGTCCTGGATCCACGGCAAGCACAGCGCCGCTGCAGCTGGCCGTGCG CCCTCACCACCGCCGCCAGGCTCCGAGGCCGCGCCCAGCCCCAGCAAGAGGAAACGGACG CCCAGCGACAAATCGGCGCATACGGTCGAACACGGCAGCCCCCGGACCCGCGACCCAACG CCGCGCCCCCCGGGGCTGCCCGAGGAGGCGACAGCCCTCGCTGCGCCCTCGCCGCCCAGG GCCCGAGCGCGCGCCGCGCCCCGGCCTCTTGGAGCCCACGGACGCCGGCGGTCCCCCGCG AAGCGCGCCGAGGCTGCCTCCATGTTGGCCGCTGACGTGCGCGGCAAGACTCGCAGCCTG GGCCGCGCCGAGGTGGCCCTGGGCGCGCAGGGCCCCAGGGAAAAGCCGGCGCCCCCACAG AAAGCCAAGCGCTCCGTGCCGCCAGCCTCGCCCGCCCGCGCGCCCCCAGCGACCGAAACC CCGGGGCCTGAGAAGGCGGCGACCGACTTGCCCGCGCCTGAGACCCCCCGGAAGAAGACC CCCATCCAGAAGCCGCCGCGCAAGAAGAGCCGGGAGGCGGCGGGCGAGCTGGGCAGGGCG GGCGCACCCACCCTGTAG
Restriction Sites	Please inquire
ACCN	NM_182895
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation	This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	NM_182895.1, NP_878315.1
RefSeq Size	3493 bp
RefSeq ORF	2598 bp
Locus ID	91179
UniProt ID	Q96GP6
Protein Families	Druggable Genome
Gene Summary	The protein encoded by this gene is similar to SCARF1/SREC-I, a scavenger receptor protein that mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). This protein has only little activity of internalizing modified low density lipoproteins (LDL), but it can interact with SCARF1 through its extracellular domain. The association of this protein with SCARF1 is suppressed by the presence of scavenger ligands. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) lacks an in-frame segment within the coding region, as compared to variant 1. The resulting isoform (2) lacks an internal region, as compared to isoform 1. CCDS Note: This CCDS representation has been updated to correct a frameshifted segment in the 3' coding region, supported by transcript and orthologous alignments, and by the update of the GRCh37 reference genome assembly to the GRCh38 assembly.

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.