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Plectin (PLEC) (NM_201382) Human Untagged Clone
CAT＃: SC308017
PLEC (untagged)-Human plectin (PLEC), nuclear gene encoding mitochondrial protein, transcript variant 8
CNY 87,590.00
货期*
详询
规格
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EBS1; EBSMD; EBSND; EBSO; EBSOG; EBSPA; HD1; LGMD2Q; LGMDR17; PCN; PLEC1; PLEC1b; PLTN |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_201382, the custom clone sequence may differ by one or more nucleotides
ATGGAGCCCTCGGGCAGCCTGTTTCCCTCCCTGGTGGTTGTGGGTCACGTTGTCACCCTG GCCGCTGTGTGGCACTGGCGCAGGGGACGTCGGTGGGCGCAGGACGAGCAAGATGAGCGG GATCGTGTGCAGAAGAAAACCTTCACCAAGTGGGTCAACAAGCACCTCATCAAGGCCCAG AGGCACATCAGTGACCTGTATGAAGACCTCCGCGATGGCCACAACCTCATCTCCCTGCTG GAGGTCCTCTCGGGGGACAGCCTGCCCCGGGAGAAGGGGAGGATGCGTTTCCACAAGCTG CAGAATGTCCAGATTGCCCTGGACTACCTCCGGCACCGCCAGGTGAAGCTGGTGAACATC AGGAATGATGACATCGCTGACGGCAACCCCAAGCTGACCCTTGGCCTCATCTGGACAATC ATTCTGCACTTCCAGATCTCAGATATCCAGGTGAGTGGGCAGTCGGAGGACATGACGGCC AAGGAGAAGCTGCTGCTGTGGTCGCAGCGAATGGTGGAGGGGTACCAGGGCCTGCGATGC GACAACTTCACCTCCAGCTGGAGAGACGGCCGCCTCTTCAATGCCATCATCCACCGGCAC AAGCCCCTGCTCATCGACATGAACAAGGTGTACCGGCAGACCAACCTGGAGAACCTGGAC CAGGCCTTCTCTGTGGCGGAGCGGGACCTGGGAGTGACGCGGCTCCTGGACCCTGAGGAC GTGGATGTCCCTCAGCCCGACGAGAAGTCCATCATCACCTACGTCTCGTCGCTGTATGAC GCCATGCCCCGCGTGCCGGACGTGCAGGATGGGGTGAGGGCCAACGAGCTGCAGCTGCGC TGGCAGGAGTACCGGGAGCTGGTGCTGCTGCTGCTTCAGTGGATGCGACACCACACGGCC GCCTTTGAGGAACGCAGGTTCCCCTCCAGCTTCGAGGAGATTGAGATCCTGTGGTCTCAG TTCCTGAAGTTTAAGGAGATGGAGCTACCAGCCAAGGAGGCCGACAAGAACAGGTCCAAG GGCATCTACCAATCCCTGGAGGGAGCGGTGCAAGCAGGCCAGCTCAAGGTGCCCCCTGGC TACCACCCGCTGGATGTGGAGAAGGAGTGGGGCAAGCTGCACGTGGCCATCCTGGAGCGG GAGAAGCAGCTCCGCAGCGAGTTTGAGAGGCTGGAGTGTCTTCAGCGCATCGTGACCAAG CTGCAGATGGAGGCGGGGCTGTGTGAGGAGCAGCTGAACCAGGCCGACGCCCTGCTGCAG TCGGATGTCCGGCTGCTGGCTGCAGGCAAAGTGCCACAGCGGGCGGGGGAGGTGGAACGG GACTTGGACAAGGCGGATAGCATGATCCGGCTGCTCTTCAACGACGTGCAGACCCTCAAG GATGGACGGCACCCGCAGGGCGAGCAGATGTACCGCAGGGTGTACCGTCTGCACGAGCGC CTGGTAGCCATCCGCACCGAGTACAACCTACGGCTGAAGGCAGGCGTGGCGGCCCCTGCA ACCCAGGTGGCCCAGGTGACTCTGCAGAGTGTGCAGAGGCGCCCCGAGCTGGAGGACTCC ACTCTGCGCTACCTGCAGGACCTGCTGGCCTGGGTGGAGGAGAACCAGCACCGTGTGGAT GGCGCTGAGTGGGGTGTGGACCTGCCCAGCGTGGAGGCGCAGCTGGGCAGCCACCGAGGC CTGCACCAGTCCATCGAAGAATTCCGGGCCAAGATCGAGCGGGCACGGAGTGACGAGGGC CAGCTCTCCCCCGCCACCCGGGGTGCCTACCGTGACTGCCTGGGTCGGCTGGACCTGCAG TACGCCAAGCTGCTGAACTCCTCCAAGGCCCGCCTCAGGTCCCTGGAGAGCTTGCACAGC TTTGTGGCAGCCGCCACTAAGGAGCTAATGTGGCTGAATGAGAAGGAGGAGGAGGAGGTG GGCTTCGACTGGAGCGACCGCAACACCAACATGACCGCCAAGAAGGAGAGCTACTCGGCG CTGATGCGGGAGCTGGAGCTGAAGGAGAAGAAGATCAAGGAGCTCCAAAATGCTGGGGAC CGGCTGCTGCGGGAGGACCACCCGGCCCGGCCCACGGTGGAGTCCTTCCAGGCGGCCCTG CAGACGCAGTGGAGCTGGATGCTACAGCTGTGCTGCTGTATCGAGGCACACCTGAAGGAG AACGCTGCCTACTTTCAGTTCTTCTCAGATGTGCGGGAGGCCGAGGGGCAGTTGCAGAAG CTGCAGGAGGCACTGCGTAGGAAATACAGTTGTGATCGCTCCGCCACCGTCACCCGGCTG GAGGACCTGCTGCAGGATGCCCAGGACGAGAAGGAACAGCTGAACGAGTACAAGGGCCAC CTCTCAGGCCTGGCCAAGCGGGCCAAGGCCGTCGTGCAGCTGAAGCCCCGCCACCCAGCC CACCCCATGCGGGGCCGCCTGCCCCTGCTGGCCGTGTGCGACTATAAGCAGGTGGAGGTG ACTGTGCACAAGGGTGACGAGTGCCAGCTGGTGGGCCCTGCACAGCCGTCCCACTGGAAG GTGCTCAGCAGCTCCGGCAGCGAGGCCGCCGTGCCCTCCGTGTGCTTCCTGGTGCCCCCG CCCAACCAGGAGGCCCAGGAGGCCGTCACCAGGCTGGAGGCCCAGCACCAGGCCCTGGTC ACGCTGTGGCACCAGTTGCACGTGGACATGAAGAGCCTTCTGGCCTGGCAGAGCCTTCGC CGCGACGTGCAGCTCATCCGCTCCTGGTCCCTGGCCACGTTCCGCACCCTGAAGCCAGAG GAGCAGCGCCAAGCCCTGCACAGCCTGGAGCTGCACTACCAGGCCTTCCTGCGGGACAGC CAGGACGCGGGCGGCTTCGGACCCGAGGACCGGCTGATGGCTGAGCGCGAGTACGGCTCC TGCAGCCACCACTACCAGCAGCTGCTGCAGAGCCTGGAACAGGGTGCACAGGAAGAGTCT CGCTGCCAGCGCTGCATCTCCGAGCTCAAAGACATCCGGCTGCAGCTGGAGGCCTGTGAG ACGCGCACCGTGCACCGCCTGCGGCTGCCGCTGGACAAAGAGCCGGCACGGGAGTGTGCC CAGCGCATCGCCGAGCAGCAGAAGGCACAGGCAGAGGTGGAGGGGCTGGGCAAGGGGGTC GCCCGGCTCTCTGCCGAGGCCGAGAAGGTCTTGGCCCTACCAGAGCCATCGCCTGCGGCC CCCACGCTGCGCTCGGAGCTGGAGCTGACGCTGGGCAAGCTGGAGCAGGTCCGCAGCCTG TCTGCCATCTACCTGGAGAAGCTCAAGACCATCAGCCTGGTGATCCGCGGCACGCAGGGG GCCGAGGAGGTGCTCAGGGCCCACGAGGAGCAGCTCAAGGAGGCCCAGGCCGTGCCGGCC ACCCTCCCGGAGCTCGAGGCCACCAAGGCCTCTCTGAAGAAGCTGCGGGCCCAGGCCGAG GCACAGCAGCCCACGTTCGACGCCCTGCGGGATGAGCTGCGGGGGGCACAGGAGGTGGGG GAGCGACTGCAGCAGCGGCACGGGGAGCGGGACGTGGAGGTGGAGCGCTGGCGGGAGCGG GTCGCCCAGTTGCTTGAGCGCTGGCAGGCTGTGCTGGCCCAGACCGACGTGCGGCAGCGC GAGCTCGAGCAACTGGGCCGCCAGCTGCGTTACTACCGCGAGAGTGCAGACCCCTTGGGC GCCTGGCTGCAGGACGCCAGGCGGCGGCAGGAGCAGATCCAGGCCATGCCGCTGGCCGAC AGCCAGGCTGTGCGGGAGCAGCTGCGGCAGGAGCAGGCCCTGCTGGAGGAGATCGAGCGC CACGGCGAGAAGGTCGAGGAGTGCCAGAGGTTTGCGAAACAGTACATCAACGCCATCAAG GACTATGAACTCCAGCTGGTGACGTACAAGGCGCAGCTTGAGCCGGTGGCCTCCCCGGCC AAGAAGCCCAAGGTCCAGTCGGGATCAGAGAGTGTCATCCAGGAGTACGTGGACCTGCGT ACGCACTACAGCGAGCTGACCACACTGACGAGCCAGTACATCAAGTTCATCAGCGAGACT CTGCGGCGCATGGAGGAGGAGGAGAGGCTGGCTGAGCAGCAGCGGGCAGAGGAGCGCGAG CGGCTGGCCGAGGTGGAGGCCGCGCTGGAGAAGCAGCGGCAGCTGGCCGAGGCGCACGCC CAGGCAAAGGCACAGGCGGAGCGGGAGGCGAAGGAGCTGCAGCAGCGCATGCAGGAGGAG GTGGTGCGGCGGGAGGAGGCGGCGGTGGACGCGCAGCAGCAGAAGCGCAGCATTCAGGAG GAGCTGCAGCAGCTGCGGCAGAGCTCGGAGGCGGAGATCCAGGCCAAGGCCCGGCAGGCA GAGGCGGCTGAGCGCAGCCGGCTGCGCATCGAGGAGGAGATCCGCGTGGTGCGCCTGCAG TTGGAGGCCACCGAGCGCCAGCGTGGCGGGGCTGAGGGGGAGCTGCAGGCACTGCGTGCA CGGGCGGAGGAGGCTGAGGCACAAAAGCGACAGGCGCAGGAGGAGGCCGAGCGCTTGCGG AGGCAGGTGCAGGACGAGAGCCAGCGTAAGCGGCAGGCGGAGGTGGAGCTGGCCTCGCGC GTGAAGGCCGAGGCCGAGGCGGCGCGCGAGAAGCAGCGGGCCCTGCAGGCCCTGGAGGAG CTGCGGCTGCAGGCGGAGGAGGCGGAGCGGCGCCTGCGGCAGGCCGAGGTGGAGCGAGCG CGGCAGGTACAGGTGGCCCTGGAGACGGCGCAGCGCAGTGCAGAGGCGGAGCTGCAGAGC AAACGCGCCTCCTTCGCCGAGAAGACGGCACAGCTGGAGCGCTCCCTGCAGGAGGAACAC GTGGCTGTGGCACAGCTGCGGGAGGAGGCTGAGCGGCGGGCACAGCAGCAGGCCGAGGCC GAGCGGGCGCGCGAGGAGGCAGAGCGGGAGCTGGAGCGCTGGCAGCTCAAGGCCAACGAG GCGCTACGGCTGCGGCTGCAGGCGGAGGAGGTGGCGCAGCAGAAGAGCCTGGCGCAGGCC GAGGCTGAGAAGCAGAAGGAGGAGGCGGAGCGCGAGGCGCGGCGGCGCGGCAAGGCGGAG GAGCAGGCCGTCCGGCAGCGGGAGCTGGCTGAACAAGAGCTGGAGAAGCAGCGGCAGCTG GCGGAAGGCACCGCGCAGCAGCGCCTGGCCGCGGAGCAGGAGTTGATCCGGCTGCGGGCC GAGACGGAGCAGGGGGAGCAGCAGCGGCAGCTGCTGGAGGAGGAGCTGGCCCGGCTGCAG CGTGAGGCGGCTGCAGCCACGCAGAAACGGCAGGAGCTGGAAGCCGAGCTGGCCAAGGTG CGGGCCGAGATGGAGGTGCTGCTGGCCAGCAAGGCGAGGGCTGAGGAGGAGTCGCGCTCC ACCAGCGAGAAGTCCAAGCAGAGGCTGGAGGCCGAGGCCGGCCGGTTCCGCGAGCTGGCC GAGGAGGCCGCCCGCCTGCGTGCCCTGGCGGAAGAGGCCAAGCGGCAGCGGCAGCTGGCC GAGGAAGACGCGGCGCGGCAGCGGGCCGAGGCGGAGCGGGTGCTTGCGGAGAAGCTGGCC GCCATCGGCGAGGCCACGCGGCTCAAGACGGAGGCGGAGATCGCGCTCAAGGAGAAGGAG GCGGAGAACGAGCGCCTGCGGCGGCTGGCGGAGGACGAGGCCTTCCAGCGGCGGCGGCTG GAGGAGCAGGCCGCGCAACACAAGGCTGACATCGAGGAGCGCCTGGCCCAGCTGCGCAAG GCATCGGACAGCGAGCTGGAGCGGCAGAAGGGGCTGGTGGAGGACACGCTGAGGCAGCGG CGGCAGGTGGAGGAGGAGATCCTGGCGCTGAAGGCGAGCTTCGAGAAGGCGGCCGCTGGC AAGGCGGAGCTGGAGCTGGAGCTGGGACGCATCCGCAGCAACGCGGAGGACACGCTGCGC AGCAAGGAGCAGGCCGAGCTGGAGGCTGCGAGGCAGCGGCAGCTGGCGGCGGAGGAGGAG CGGCGGCGCCGTGAGGCTGAGGAGCGCGTGCAGAAGAGCCTGGCGGCCGAGGAGGAGGCC GCACGGCAGCGGAAGGCGGCGCTGGAGGAAGTCGAGCGGCTGAAAGCCAAGGTGGAGGAG GCGCGGCGCCTGCGGGAGCGAGCGGAGCAGGAGTCGGCGCGGCAGCTGCAGCTGGCCCAG GAGGCCGCCCAGAAGCGGCTGCAGGCGGAAGAGAAGGCACACGCCTTCGCGGTGCAGCAG AAGGAGCAGGAGCTACAGCAGACGCTGCAGCAGGAGCAGAGCGTGCTGGACCAGCTGCGC GGCGAGGCGGAGGCGGCCCGGCGGGCGGCTGAGGAGGCGGAGGAGGCCCGGGTGCAGGCG GAGCGTGAGGCGGCGCAGTCCCGGCGGCAGGTGGAAGAGGCCGAGCGGCTGAAGCAGTCG GCAGAGGAGCAGGCACAGGCCCGGGCTCAGGCACAGGCGGCTGCAGAGAAGCTGCGCAAG GAGGCCGAGCAAGAGGCGGCGCGGCGGGCACAGGCGGAGCAGGCGGCCCTGCGGCAGAAG CAGGCAGCTGACGCGGAGATGGAGAAGCATAAGAAATTCGCCGAGCAGACGCTGCGGCAG AAGGCGCAGGTGGAGCAGGAGCTGACAACACTGCGGCTGCAGCTGGAGGAGACCGACCAC CAGAAGAACCTGCTGGACGAGGAGCTGCAGCGGCTGAAGGCGGAGGCCACGGAGGCCGCA CGCCAGCGCAGCCAGGTGGAGGAGGAGCTCTTCTCGGTGCGCGTGCAGATGGAGGAGCTG AGCAAGCTCAAGGCACGCATCGAGGCTGAGAACCGCGCACTCATCTTGCGTGACAAGGAC AATACGCAGCGCTTCCTGCAGGAGGAGGCTGAGAAGATGAAGCAGGTGGCGGAGGAGGCC GCGCGGCTGAGTGTGGCGGCCCAAGAGGCTGCGCGACTGCGGCAGCTGGCAGAGGAGGAC CTGGCACAGCAGCGGGCCTTGGCAGAGAAGATGCTCAAGGAGAAGATGCAGGCGGTGCAG GAGGCCACGCGACTCAAGGCTGAGGCGGAACTGCTGCAGCAGCAGAAGGAGCTTGCGCAG GAGCAGGCGCGGCGGCTGCAGGAGGACAAGGAGCAGATGGCGCAGCAGCTGGCGGAGGAG ACGCAGGGCTTCCAGCGGACGCTGGAGGCCGAGCGGCAGCGGCAGCTGGAGATGAGCGCT GAGGCTGAGCGCCTCAAGCTGCGTGTGGCCGAGATGAGCCGAGCCCAGGCCCGCGCTGAG GAGGACGCCCAGCGCTTCCGGAAGCAGGCGGAGGAGATCGGTGAGAAGCTGCACCGCACG GAGCTCGCCACCCAGGAGAAGGTGACCCTGGTGCAGACACTGGAGATCCAGCGACAGCAG AGTGACCATGATGCCGAGCGCCTGCGGGAGGCCATCGCTGAGCTGGAGCGTGAGAAGGAG AAGCTCCAACAGGAGGCCAAACTGCTGCAGCTCAAGTCTGAGGAGATGCAGACGGTGCAG CAGGAGCAGCTGCTGCAGGAGACGCAGGCCCTGCAGCAAAGCTTCCTCTCTGAAAAGGAC AGCCTGCTACAGCGGGAGCGCTTCATCGAGCAGGAGAAGGCCAAGCTGGAGCAGCTCTTC CAGGACGAGGTGGCCAAGGCACAGCAGCTGCGTGAGGAGCAGCAGCGGCAGCAGCAGCAG ATGGAGCAGGAACGGCAGCGGCTGGTGGCCAGCATGGAGGAGGCGCGGCGGCGGCAGCAT GAGGCCGAGGAGGGCGTGCGGCGCAAGCAGGAGGAGCTGCAGCAGCTGGAGCAGCAGCGG CGGCAGCAGGAGGAGCTGCTGGCTGAGGAGAACCAGAGGCTGCGTGAGCAGCTGCAGCTC CTGGAGGAGCAGCACCGGGCCGCGCTGGCGCACTCAGAGGAGGTCACTGCCTCGCAGGTG GCTGCCACAAAGACCCTGCCCAATGGCCGGGATGCACTTGATGGCCCCGCGGCAGAGGCA GAGCCGGAGCACAGCTTCGATGGCCTGCGGCGGAAGGTGTCAGCTCAGAGGCTGCAGGAG GCCGGCATCCTGAGTGCGGAGGAGCTGCAGCGGTTGGCGCAGGGCCACACCACGGTGGAC GAGCTCGCACGGCGGGAAGACGTGCGCCACTACCTGCAGGGCCGCAGCAGTATCGCAGGG CTGTTGCTGAAGGCCACCAATGAGAAGCTGAGTGTTTACGCCGCCCTGCAGAGGCAGCTG CTGAGTCCCGGCACGGCCCTCATCCTGCTGGAGGCGCAGGCGGCCTCAGGCTTCCTGCTG GACCCTGTGCGGAACCGGCGGCTGACCGTCAACGAGGCTGTGAAGGAGGGTGTGGTGGGC CCCGAGCTGCACCACAAGCTGCTGTCGGCCGAGCGCGCCGTCACTGGCTACAAGGACCCC TACACTGGCCAGCAGATCTCTCTCTTCCAAGCCATGCAGAAGGGCCTCATCGTCCGGGAG CACGGCATCCGCCTGCTGGAGGCCCAGATCGCCACGGGCGGCGTTATCGACCCCGTGCAC AGCCACCGCGTGCCCGTGGACGTGGCCTACCGGCGCGGCTACTTCGACGAGGAGATGAAC CGCGTCCTGGCGGACCCCAGCGACGACACCAAGGGCTTCTTTGACCCCAACACGCACGAG AACCTCACGTACCTGCAGCTACTGGAGCGCTGCGTGGAGGACCCCGAGACGGGCCTGTGC CTTCTGCCACTCACGGATAAGGCTGCCAAGGGCGGGGAGCTGGTCTACACTGACTCCGAG GCCCGGGACGTCTTTGAGAAGGCCACCGTGTCTGCGCCGTTCGGCAAGTTCCAGGGCAAG ACGGTGACCATTTGGGAGATCATCAACTCGGAATACTTCACGGCAGAGCAGCGGCGGGAC CTGCTGCGGCAGTTCCGCACGGGCCGGATCACAGTGGAGAAGATCATCAAGATCATCATC ACGGTGGTGGAGGAGCAGGAGCAGAAGGGCCGGCTTTGCTTTGAGGGCCTGCGCAGCCTG GTGCCAGCCGCCGAGCTGCTGGAGAGCAGGGTCATCGACCGCGAGCTCTACCAGCAGCTG CAGCGAGGTGAGCGCTCTGTGCGAGACGTAGCCGAGGTGGACACTGTGCGGCGGGCTCTC CGGGGTGCCAACGTCATCGCGGGTGTATGGCTGGAGGAGGCGGGGCAGAAGCTGAGTATC TACAATGCCCTGAAGAAAGACCTGCTGCCATCCGACATGGCCGTGGCCCTGTTGGAAGCC CAGGCCGGCACCGGGCACATCATCGACCCCGCCACCAGCGCCCGGCTGACCGTGGACGAG GCAGTGCGTGCTGGCCTGGTGGGCCCCGAGTTTCATGAGAAGCTGCTATCAGCCGAGAAG GCTGTGACAGGGTACAGGGACCCCTACACAGGGCAGAGCGTCTCCCTGTTCCAGGCCCTG AAGAAGGGCCTCATTCCCCGGGAGCAGGGCCTGCGCCTGTTGGACGCCCAGCTGTCCACG GGCGGCATCGTGGACCCCAGCAAGAGCCACCGCGTGCCCCTGGATGTCGCCTGCGCCCGA GGCTGCCTGGATGAGGAGACCAGCAGGGCCCTGTCGGCACCAAGGGCCGACGCCAAGGCC TACAGTGACCCCAGCACAGGGGAGCCGGCCACCTACGGCGAGCTCCAGCAGCGGTGCCGG CCCGACCAGCTGACCGGGCTGAGCCTGCTGCCGCTCTCAGAAAAGGCTGCTCGGGCCCGG CAGGAGGAGCTCTACTCAGAGCTGCAGGCCCGTGAGACCTTTGAAAAGACCCCGGTTGAG GTCCCCGTGGGTGGCTTCAAGGGCAGGACGGTGACGGTGTGGGAGCTCATCAGCTCTGAG TACTTCACTGCGGAGCAGCGGCAGGAGCTGTTGCGTCAGTTCCGCACGGGCAAGGTCACC GTGGAGAAGGTCATCAAGATTCTCATTACCATCGTGGAGGAGGTGGAGACCCTGCGGCAG GAGAGGCTGTCCTTCAGCGGCCTCCGTGCCCCTGTGCCAGCCAGCGAGCTCCTGGCTTCC GGGGTCCTCAGCAGAGCCCAGTTTGAGCAGCTCAAGGACGGCAAGACGACGGTCAAGGAC CTTTCGGAGCTGGGCTCCGTGCGGACGCTGCTGCAGGGCAGTGGCTGCCTCGCCGGCATC TACCTGGAGGACACCAAGGAGAAGGTGTCCATCTACGAGGCCATGCGCCGGGGCCTGCTG AGAGCCACAACGGCTGCGCTCCTGCTGGAGGCGCAGGCGGCCACTGGCTTCCTGGTGGAC CCCGTGCGGAACCAGCGCCTGTATGTCCACGAGGCCGTGAAGGCGGGCGTGGTGGGCCCC GAGCTTCACGAGCAGCTGCTGTCTGCCGAGAAGGCCGTCACCGGCTACAGAGACCCCTAC TCGGGCAGCACCATCTCCCTCTTCCAGGCCATGCAGAAGGGCCTGGTTCTCCGGCAGCAC GGCATCCGCCTGCTGGAGGCCCAGATCGCCACGGGCGGCATCATCGACCCCGTGCACAGC CACCGCGTGCCTGTGGACGTGGCCTACCAGCGCGGCTACTTCAGTGAGGAGATGAACCGC GTCCTGGCGGACCCCAGCGACGACACCAAGGGCTTCTTTGACCCCAACACGCATGAGAAC CTCACGTACAGGCAGCTGCTGGAGCGGTGCGTGGAGGACCCCGAGACGGGCTTGCGCCTT CTGCCACTGAAAGGGGCGGAGAAGGCTGAGGTGGTGGAGACCACGCAGGTGTACACTGAG GAGGAGACAAGAAGGGCATTTGAAGAGACACAGATCGACATTCCCGGCGGCGGCAGCCAC GGCGGCTCCACCATGTCCCTGTGGGAGGTGATGCAGTCGGACCTGATCCCCGAGGAGCAG CGGGCCCAGCTGATGGCTGACTTCCAGGCCGGCCGGGTGACCAAGGAACGCATGATCATC ATCATCATCGAGATCATTGAGAAGACAGAGATCATCCGCCAGCAGGGTCTGGCCTCCTAC GACTACGTGCGCCGCCGCCTCACGGCTGAGGACCTGTTCGAGGCTCGGATCATCTCTCTC GAGACCTACAACCTGCTCCGGGAGGGCACCAGGAGCCTCCGTGAGGCTCTCGAGGCGGAG TCCGCCTGGTGCTACCTCTATGGCACGGGCTCCGTGGCTGGTGTCTACCTGCCCGGTTCC AGGCAGACACTGAGCATCTACCAGGCTCTCAAGAAAGGGCTGCTGAGTGCCGAGGTGGCC CGCCTGCTGCTGGAGGCACAGGCAGCCACAGGCTTCCTGCTGGACCCGGTGAAGGGGGAG CGGCTGACTGTGGATGAGGCTGTGCGGAAGGGCCTCGTGGGGCCCGAGCTGCACGACCGC CTGCTCTCGGCTGAGCGGGCGGTCACCGGCTACCGTGACCCCTACACCGAGCAGACCATC TCGCTCTTCCAGGCCATGAAGAAGGAGCTGATCCCTACTGAGGAGGCCCTGCGGCTGCTG GATGCCCAGCTGGCCACCGGCGGCATCGTGGACCCCCGCCTGGGCTTCCACCTTCCCCTG GAGGTGGCTTACCAGCGTGGCTACCTCAACAAGGACACGCACGACCAGCTGTCAGAGCCC AGCGAGGTGCGCAGCTACGTGGACCCGTCCACCGACGAGCGCCTCAGCTACACGCAGCTG CTCAGGCGGTGCCGTCGTGACGACGGCACCGGCCAGCTGCTCCTGCCACTGTCGGACGCC CGCAAGCTGACCTTCCGTGGCCTGCGGAAGCAGATCACCATGGAGGAGCTGGTGCGCTCG CAGGTCATGGACGAGGCCACGGCGCTGCAGCTGCGGGAGGGCCTGACCTCCATCGAGGAG GTCACCAAGAACTTGCAGAAGTTCCTGGAAGGCACCAGCTGCATCGCTGGTGTCTTCGTG GACGCCACCAAGGAACGGCTCTCGGTGTACCAGGCCATGAAGAAGGGCATCATCCGCCCC GGCACAGCCTTTGAGCTCCTGGAGGCGCAGGCGGCCACCGGTTACGTCATCGACCCCATC AAGGGACTGAAGCTGACGGTGGAGGAGGCTGTGCGTATGGGCATTGTGGGCCCCGAGTTC AAGGACAAGCTGCTGTCGGCCGAGCGCGCCGTCACTGGGTACAAGGACCCCTACTCTGGG AAGCTCATCTCCCTCTTCCAGGCCATGAAGAAGGGCCTGATCCTGAAGGACCATGGCATC CGCCTGCTGGAGGCCCAGATCGCCACGGGCGGCATCATCGACCCTGAGGAGAGCCACCGG CTGCCCGTGGAGGTGGCCTACAAGCGCGGCCTCTTCGATGAGGAGATGAACGAGATCCTG ACCGACCCCTCGGACGACACCAAGGGCTTCTTTGACCCTAACACGGAGGAGAACCTCACC TACCTGCAGCTGATGGAGCGTTGTATCACTGACCCCCAGACGGGCCTGTGTCTCTTGCCG CTGAAGGAGAAGAAGCGGGAGCGGAAGACGTCCTCCAAGTCCTCCGTGCGCAAGCGCCGA GTGGTCATCGTGGACCCCGAGACGGGCAAGGAGATGTCAGTGTACGAGGCCTACCGCAAG GGCCTGATTGACCACCAGACGTACCTGGAGCTGTCCGAGCAGGAGTGCGAGTGGGAGGAG ATCACCATCTCCTCCTCGGACGGCGTGGTCAAGTCCATGATCATCGACCGCCGCTCCGGG CGCCAGTACGACATCGATGATGCCATCGCCAAGAACCTCATCGACCGCTCGGCACTGGAC CAGTACCGCGCCGGCACGCTCTCCATCACCGAGTTCGCCGACATGCTCTCGGGCAACGCC GGTGGTTTCCGCTCCCGTTCCTCCTCGGTGGGATCCTCCTCCTCCTACCCCATCAGCCCC GCCGTCTCCAGGACCCAGCTGGCCTCCTGGTCAGACCCCACTGAGGAGACGGGCCCCGTG GCTGGCATCCTGGACACGGAGACGCTGGAGAAGGTGTCCATCACCGAGGCCATGCACCGG AACCTGGTGGATAACATCACGGGGCAGCGGCTGCTGGAGGCGCAGGCCTGCACCGGGGGC ATCATCGACCCCAGCACCGGTGAGCGCTTCCCTGTCACCGACGCCGTCAACAAGGGCCTG GTGGACAAGATCATGGTGGACCGCATCAACCTGGCCCAGAAGGCCTTCTGCGGCTTCGAG GACCCACGCACCAAGACCAAGATGTCGGCCGCCCAGGCCCTGAAGAAGGGCTGGCTCTAC TACGAGGCCGGCCAGCGCTTCCTGGAGGTGCAGTACCTGACCGGCGGCTTGATCGAGCCC GACACGCCGGGCCGCGTGCCCCTGGACGAGGCCCTGCAGCGCGGCACGGTGGACGCCCGC ACCGCACAGAAGCTGCGTGACGTGGGCGCCTACTCCAAGTACCTCACCTGCCCTAAGACC AAGCTCAAGATCTCCTATAAGGACGCGCTGGACCGCAGCATGGTGGAGGAGGGCACGGGG CTGCGGCTGCTGGAGGCTGCCGCGCAGTCCACCAAGGGCTACTACAGCCCCTACAGCGTC AGCGGCTCCGGCTCTACCGCTGGCTCCCGCACCGGCTCGCGCACCGGCTCCCGGGCCGGC TCCCGCCGCGGCAGCTTTGACGCCACCGGCTCCGGCTTCTCCATGACCTTCTCTTCATCC TCCTACTCCTCCTCGGGCTACGGCCGCCGCTACGCCTCGGGGTCCTCGGCCTCCCTGGGG GGCCCTGAGTCTGCCGTGGCCTGA |
| Restriction Sites | Please inquire |
| ACCN | NM_201382 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_201382.1, NP_958784.1 |
| RefSeq Size | 14675 bp |
| RefSeq ORF | 13644 bp |
| Locus ID | 5339 |
| UniProt ID | Q15149 |
| Protein Families | Druggable Genome |
| Gene Summary | Plectin is a prominent member of an important family of structurally and in part functionally related proteins, termed plakins or cytolinkers, that are capable of interlinking different elements of the cytoskeleton. Plakins, with their multi-domain structure and enormous size, not only play crucial roles in maintaining cell and tissue integrity and orchestrating dynamic changes in cytoarchitecture and cell shape, but also serve as scaffolding platforms for the assembly, positioning, and regulation of signaling complexes (reviewed in PMID: 9701547, 11854008, and 17499243). Plectin is expressed as several protein isoforms in a wide range of cell types and tissues from a single gene located on chromosome 8 in humans (PMID: 8633055, 8698233). Until 2010, this locus was named plectin 1 (symbol PLEC1 in human; Plec1 in mouse and rat) and the gene product had been referred to as "hemidesmosomal protein 1" or "plectin 1, intermediate filament binding 500kDa". These names were superseded by plectin. The plectin gene locus in mouse on chromosome 15 has been analyzed in detail (PMID: 10556294, 14559777), revealing a genomic exon-intron organization with well over 40 exons spanning over 62 kb and an unusual 5' transcript complexity of plectin isoforms. Eleven exons (1-1j) have been identified that alternatively splice directly into a common exon 2 which is the first exon to encode plectin's highly conserved actin binding domain (ABD). Three additional exons (-1, 0a, and 0) splice into an alternative first coding exon (1c), and two additional exons (2alpha and 3alpha) are optionally spliced within the exons encoding the acting binding domain (exons 2-8). Analysis of the human locus has identified eight of the eleven alternative 5' exons found in mouse and rat (PMID: 14672974); exons 1i, 1j and 1h have not been confirmed in human. Furthermore, isoforms lacking the central rod domain encoded by exon 31 have been detected in mouse (PMID:10556294), rat (PMID: 9177781), and human (PMID: 11441066, 10780662, 20052759). The short alternative amino-terminal sequences encoded by the different first exons direct the targeting of the various isoforms to distinct subcellular locations (PMID: 14559777). As the expression of specific plectin isoforms was found to be dependent on cell type (tissue) and stage of development (PMID: 10556294, 12542521, 17389230) it appears that each cell type (tissue) contains a unique set (proportion and composition) of plectin isoforms, as if custom-made for specific requirements of the particular cells. Concordantly, individual isoforms were found to carry out distinct and specific functions (PMID: 14559777, 12542521, 18541706). In 1996, a number of groups reported that patients suffering from epidermolysis bullosa simplex with muscular dystrophy (EBS-MD) lacked plectin expression in skin and muscle tissues due to defects in the plectin gene (PMID: 8698233, 8941634, 8636409, 8894687, 8696340). Two other subtypes of plectin-related EBS have been described: EBS-pyloric atresia (PA) and EBS-Ogna. For reviews of plectin-related diseases see PMID: 15810881, 19945614. Mutations in the plectin gene related to human diseases should be named based on the position in NM_000445 (variant 1, isoform 1c), unless the mutation is located within one of the other alternative first exons, in which case the position in the respective Reference Sequence should be used. [provided by RefSeq, Aug 2011] Transcript Variant: This variant (8) differs in the 5' UTR and the 5' coding region compared to variant 1. The resulting protein (isoform 1b) contains a distinct N-terminus compared to isoform 1c. Plectin isoform 1b has been found to associate exclusively with mitochondria (PMID: 18541706, 14559777). |
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