CtIP (RBBP8) (NM_203292) Human Untagged Clone
CAT#: SC308103
RBBP8 (untagged)-Human retinoblastoma binding protein 8 (RBBP8), transcript variant 3
CNY 16,720.00
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | COM1; CTIP; JWDS; RIM; SAE2; SCKL2 |
Vector | pCMV6 series |
Sequence Data |
>NCBI ORF sequence for NM_203292, the custom clone sequence may differ by one or more nucleotides
ATGAACATCTCGGGAAGCAGCTGTGGAAGCCCTAACTCTGCAGATACATCTAGTGACTTT AAGGACCTTTGGACAAAACTAAAAGAATGTCATGATAGAGAAGTACAAGGTTTACAAGTA AAAGTAACCAAGCTAAAACAGGAACGAATCTTAGATGCACAAAGACTAGAAGAATTCTTC ACCAAAAATCAACAGCTGAGGGAACAGCAGAAAGTCCTTCATGAAACCATTAAAGTTTTA GAAGATCGGTTAAGAGCAGGCTTATGTGATCGCTGTGCAGTAACTGAAGAACATATGCGG AAAAAACAGCAAGAGTTTGAAAATATCCGGCAGCAGAATCTTAAACTTATTACAGAACTT ATGAATGAAAGGAATACTCTACAGGAAGAAAATAAAAAGCTTTCTGAACAACTCCAGCAG AAAATTGAGAATGATCAACAGCATCAAGCAGCTGAGCTTGAATGTGAGGAAGACGTTATT CCAGATTCACCGATAACAGCCTTCTCATTTTCTGGCGTTAACCGGCTACGAAGAAAGGAG AACCCCCATGTCCGATACATAGAACAAACACATACTAAATTGGAGCACTCTGTGTGTGCA AATGAAATGAGAAAAGTTTCCAAGTCTTCAACTCATCCACAACATAATCCTAATGAAAAT GAAATTCTAGTAGCTGACACTTATGACCAAAGTCAATCTCCAATGGCCAAAGCACATGGA ACAAGCAGCTATACCCCTGATAAGTCATCTTTTAATTTAGCTACAGTTGTTGCTGAAACA CTTGGACTTGGTGTTCAAGAAGAATCTGAAACTCAAGGTCCCATGAGCCCCCTTGGTGAT GAGCTCTACCACTGTCTGGAAGGAAATCACAAGAAACAGCCTTTTGAGGAATCTACAAGA AATACTGAAGATAGTTTAAGATTTTCAGATTCTACTTCAAAGACTCCTCCTCAAGAAGAA TTACCTACTCGAGTGTCATCTCCTGTATTTGGAGCTACCTCTAGTATCAAAAGTGGTTTA GATTTGAATACAAGTTTGTCCCCTTCTCTTTTACAGCCTGGGAAAAAAAAACATCTGAAA ACACTCCCTTTTAGCAACACTTGTATATCTAGATTAGAAAAAACTAGATCAAAATCTGAA GATAGTGCCCTTTTCACACATCACAGTCTTGGGTCTGAAGTGAACAAGATCATTATCCAG TCATCTAATAAACAGATACTTATAAATAAAAATATAAGTGAATCCCTAGGTGAACAGAAT AGGACTGAGTACGGTAAAGATTCTAACACTGATAAACATTTGGAGCCCCTGAAATCATTG GGAGGCCGAACATCCAAAAGGAAGAAAACTGAGGAAGAAAGTGAACATGAAGTAAGCTGC CCCCAAGCTTCTTTTGATAAAGAAAATGCTTTCCCTTTTCCAATGGATAATCAGTTTTCC ATGAATGGAGACTGTGTGATGGATAAACCTCTGGATCTGTCTGATCGATTTTCAGCTATT CAGCGTCAAGAGAAAAGCCAAGGAAGTGAGACTTCTAAAAACAAATTTAGGCAAGTGACT CTTTATGAGGCTTTGAAGACCATTCCAAAGGGCTTTTCCTCAAGCCGTAAGGCCTCAGAT GGCAACTGCACGTTGCCCAAAGATTCCCCAGGGGAGCCCTGTTCACAGGAATGCATCATC CTTCAGCCCTTGAATAAATGCTCTCCAGACAATAAACCATCATTACAAATAAAAGAAGAA AATGCTGTCTTTAAAATTCCTCTACGTCCACGTGAAAGTTTGGAGACTGAGAATGTTTTA GATGACATAAAGAGTGCTGGTTCTCATGAGCCAATAAAAATACAAACCAGGTCAGACCAT GGAGGATGTGAACTTGCATCAGTTCTTCAGTTAAATCCATGTAGAACTGGTAAAATAAAG TCTCTACAAAACAACCAAGATGTATCCTTTGAAAATATCCAGTGGAGTATAGATCCGGGA GCAGACCTTTCTCAGTATAAAATGGATGTTACTGTAATAGATACAAAGGATGGCAGTCAG TCAAAATTAGGAGGAGAGACAGTGGACATGGACTGTACATTGGTTAGTGAAACCGTTCTC TTAAAAATGAAGAAGCAAGAGCAGAAGGGAGAAAAAAGTTCAAATGAAGAAAGAAAAATG AATGATAGCTTGGAAGATATGTTTGATCGGACAACACATGAAGAGTATGAATCCTGTTTG GCAGACAGTTTCTCCCAAGCAGCAGATGAAGAGGAGGAATTGTCTACTGCCACAAAGAAA CTACACACTCATGGTGATAAACAAGACAAAGTCAAGCAGAAAGCGTTTGTGGAGCCGTAT TTTAAAGGTGATGAAAGTATTATGCAGATATGCCAGCAGAAGAAAGAGAAAAGAAATTGG CTTCCTGCTCAAGACACCGATTCCGCTACATTCCACCCAACACACCAGAGAATTTTTGGG AAGTTGGTTTTCCTTCCACTCAGACTTGTATGGAAAGAGGTTATATTAAGGAAGATCTTG ATCCTTGTCCTCGTCCAAAAAGACGTCAGCCTTACAACGCAATATTTTCTCCAAAAGGCA AGGAGCAGAAGACATAGACGTTGA |
Restriction Sites | Please inquire |
ACCN | NM_203292 |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_203292.1, NP_976037.1 |
RefSeq Size | 3233 bp |
RefSeq ORF | 2604 bp |
Locus ID | 5932 |
UniProt ID | Q99708 |
Gene Summary | The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (3) differs in the 5' UTR and lacks an alternate exon compared to variant 1, that causes a frameshift. The resulting isoform (b) is shorter and has a distinct C-terminus compared to isoform a. |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC214904 | RBBP8 (Myc-DDK-tagged)-Human retinoblastoma binding protein 8 (RBBP8), transcript variant 3 |
CNY 9,220.00 |
|
RC214904L3 | Lenti-ORF clone of RBBP8 (Myc-DDK-tagged)-Human retinoblastoma binding protein 8 (RBBP8), transcript variant 3 |
CNY 11,120.00 |
|
RC214904L4 | Lenti-ORF clone of RBBP8 (mGFP-tagged)-Human retinoblastoma binding protein 8 (RBBP8), transcript variant 3 |
CNY 11,120.00 |
|
RG214904 | RBBP8 (tGFP-tagged) - Human retinoblastoma binding protein 8 (RBBP8), transcript variant 3 |
CNY 10,170.00 |