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ATP7A (NM_000052) Human Untagged Clone
CAT＃: SC308719
ATP7A (untagged)-Human ATPase, Cu++ transporting, alpha polypeptide (ATP7A)
CNY 15,408.00
货期*
现货
规格
| Cited in 1 publication. |
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DSMAX; MK; MNK; SMAX3 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_000052 edited
CCGCCGCAGCCGCAGCTACTGTGACTTCTCCGATTGTGTGAGCTTTGTTGGAGCCTGCGT ACGTGGATTTATCGCTGCCACGGTCTGCGTAGCTCCAGAGGTTTAACCATAGGATAGAGA AACCAGGAATGTAATGAGGAAATCAAAATGGATCCAAGTATGGGTGTGAATTCTGTTACC ATTTCTGTTGAGGGTATGACTTGCAATTCCTGTGTTTGGACCATTGAGCAGCAGATTGGA AAAGTGAATGGTGTGCATCACATTAAGGTATCACTGGAAGAAAAAAATGCAACTATTATT TATGACCCTAAACTACAGACTCCAAAGACCCTACAGGAAGCTATTGATGACATGGGCTTT GATGCTGTTATCCATAATCCTGACCCTCTCCCTGTTTTAACTGACACCTTGTTTCTGACT GTTACGGCGTCACTGACTTTGCCATGGGACCATATCCAAAGCACATTGCTGAAGACCAAG GGTGTGACAGACATTAAAATTTACCCTCAGAAAAGAACTGTAGCAGTGACAATAATCCCT TCTATAGTGAATGCCAATCAGATAAAAGAGCTGGTTCCAGAACTCAGTTTAGATACTGGG ACACTGGAGAAAAAGTCAGGAGCTTGTGAAGATCATAGTATGGCTCAAGCTGGTGAAGTC GTGCTGAAGATGAAAGTGGAAGGGATGACCTGCCATTCATGTACTAGCACTATTGAAGGA AAAATTGGGAAACTGCAAGGTGTTCAGCGAATTAAAGTCTCCCTGGACAATCAAGAAGCT ACTATTGTTTATCAACCTCATCTTATCTCAGTAGAGGAAATGAAAAAGCAGATTGAAGCT ATGGGCTTTCCAGCATTTGTCAAAAAGCAGCCCAAGTACCTCAAATTGGGAGCTATTGAT GTAGAACGTCTAAAGAACACACCAGTTAAATCCTCAGAAGGGTCACAGCAAAGGAGTCCA TCATATACCAATGATTCAACAGCCACTTTCATCATTGATGGCATGCATTGTAAATCATGT GTGTCAAATATTGAAAGTACTTTATCTGCACTCCAATATGTAAGCAGCATAGTAGTTTCT TTAGAGAATAGGTCTGCCATTGTGAAGTATAATGCAAGCTCAGTCACTCCAGAATCCCTG AGAAAAGCAATAGAGGCTGTATCACCGGGGCTATATAGAGTTAGTATCACAAGTGAAGTT GAGAGTACCTCAAACTCTCCCTCCAGCTCATCTCTTCAGAAGATTCCTTTGAATGTAGTT AGCCAGCCTCTGACACAAGAAACTGTGATAAACATTGATGGCATGACTTGTAATTCCTGT GTGCAGTCTATTGAGGGTGTCATATCAAAAAAGCCAGGTGTAAAATCCATACGAGTCTCC CTTGCAAATAGCAATGGGACTGTTGAGTATGATCCTCTACTAACCTCTCCAGAAACGTTG AGAGGAGCAATAGAAGACATGGGATTTGATGCTACCTTGTCAGACACGAATGAGCCGTTG GTAGTAATAGCTCAGCCTTCATCGGAAATGCCGCTTTTGACTTCAACTAATGAATTTTAT ACTAAAGGGATGACACCAGTTCAAGACAAGGAGGAAGGAAAGAATTCATCTAAGTGTTAC ATACAGGTCACTGGCATGACTTGCGCTTCCTGTGTAGCAAACATTGAACGGAATTTAAGG CGGGAAGAAGGAATATATTCTATACTTGTGGCCCTGATGGCTGGCAAGGCAGAAGTAAGG TATAATCCTGCTGTTATACAACCCCCAATGATAGCAGAGTTCATCCGAGAACTTGGATTT GGAGCCACTGTGATAGAAAATGCTGATGAAGGAGATGGTGTTTTGGAACTTGTTGTGAGG GGAATGACGTGTGCCTCCTGCGTACATAAAATAGAGTCTAGTCTCACAAAACACAGAGGG ATCCTATACTGCTCCGTGGCCCTGGCAACCAACAAAGCACATATTAAATATGACCCAGAA ATTATTGGTCCTAGAGATATTATCCATACAATTGAAAGCTTAGGTTTTGAAGCTTCTTTG GTCAAGAAGGATCGGTCAGCAAGTCACTTAGATCATAAACGAGAAATAAGACAATGGAGA CGGTCTTTTCTTGTGAGTCTGTTTTTCTGTATTCCTGTAATGGGGCTGATGATATATATG ATGGTTATGGACCACCACTTTGCAACTCTTCACCATAATCAAAACATGAGTAAAGAAGAA ATGATCAACCTTCATTCTTCTATGTTCCTGGAGCGCCAGATTCTTCCAGGATTGTCTGTT ATGAATTTGCTGTCCTTTTTATTGTGTGTACCTGTACAGTTTTTCGGAGGCTGGTACTTC TACATTCAGGCTTATAAAGCACTGAAGCATAAGACAGCAAATATGGACGTACTGATTGTG CTGGCAACCACCATTGCATTTGCCTACTCTTTGATTATTCTTCTAGTTGCAATGTATGAG AGAGCCAAAGTGAACCCTATTACTTTCTTTGACACACCCCCTATGCTGTTTGTGTTTATT GCACTAGGCCGATGGCTGGAACATATAGCAAAGGGCAAAACATCAGAGGCTCTTGCAAAG TTAATTTCACTACAAGCTACAGAAGCAACTATTGTAACTCTTGATTCTGATAATATCCTC CTCAGTGAAGAACAAGTGGATGTGGAACTTGTACAACGTGGAGATATCATTAAAGTAGTT CCAGGAGGCAAATTTCCAGTGGATGGTCGTGTTATTGAAGGACATTCTATGGTAGATGAG TCCCTCATCACAGGGGAGGCAATGCCTGTGGCTAAGAAACCTGGCAGCACAGTGATTGCT GGTTCCATTAACCAGAACGGGTCACTGCTTATCTGCGCAACACATGTTGGAGCAGACACA ACCCTTTCTCAAATTGTCAAACTTGTGGAAGAGGCACAAACATCAAAGGCTCCTATCCAG CAGTTTGCAGACAAACTCAGTGGCTATTTTGTTCCTTTTATTGTTTTTGTTTCCATTGCC ACCCTCTTGGTATGGATTGTAATTGGATTTCTGAATTTTGAAATTGTGGAAACCTACTTT CCTGGCTACAATAGAAGTATCTCCCGAACAGAAACGATAATACGATTTGCTTTCCAAGCC TCTATCACAGTTCTGTGTATTGCATGTCCCTGTTCACTGGGACTGGCCACTCCAACTGCT GTGATGGTGGGTACAGGAGTAGGTGCTCAAAATGGCATACTAATAAAAGGTGGAGAGCCA TTGGAGATGGCTCATAAGGTAAAGGTAGTGGTATTTGATAAGACTGGAACCATTACTCAC GGAACCCCAGTGGTGAATCAAGTAAAGGTTCTAACTGAAAGTAACAGAATATCACACCAT AAAATCTTGGCCATTGTGGGAACTGCTGAAAGTAACAGTGAACACCCTCTAGGAACAGCC ATAACCAAATATTGCAAACAGGAGCTGGACACTGAAACCTTGGGTACCTGCATAGATTTC CAGGTTGTGCCAGGCTGTGGTATTAGCTGTAAAGTCACCAATATTGAAGGCTTGCTACAT AAGAATAACTGGAATATAGAGGACAATAATATTAAAAATGCATCCCTGGTTCAAATTGAT GCCAGTAATGAACAGTCATCAACTTCGTCTTCCATGATTATTGATGCCCAGATCTCAAAT GCTCTTAATGCTCAGCAGTATAAAGTCCTCATTGGTAACCGGGAGTGGATGATTAGAAAT GGTCTTGTCATTAATAACGATGTAAATGATTTCATGACTGAACATGAGAGAAAAGGTCGG ACTGCTGTATTAGTAGCAGTTGATGATGAGCTGTGTGGCTTGATAGCCATTGCAGACACA GTGAAGCCTGAAGCAGAACTGGCTATCCATATTCTGAAATCTATGGGCTTAGAAGTAGTT CTGATGACTGGAGACAACAGTAAAACAGCTAGATCTATTGCTTCTCAGGTTGGCATTACT AAGGTGTTTGCTGAAGTTCTACCTTCTCACAAGGTTGCTAAAGTGAAGCAACTTCAAGAG GAGGGGAAACGGGTAGCAATGGTGGGAGATGGAATCAATGACTCCCCAGCTCTGGCAATG GCTAATGTGGGAATTGCTATTGGCACAGGCACAGATGTAGCCATTGAAGCAGCTGATGTG GTTTTGATAAGGAATGATCTTCTGGATGTAGTGGCAAGTATTGACTTATCAAGAAAGACA GTCAAGAGGATTCGGATAAATTTTGTCTTTGCTCTAATTTATAATCTGGTTGGAATTCCC ATAGCTGCTGGAGTTTTTATGCCCATTGGTTTGGTTTTGCAGCCCTGGATGGGATCTGCA GCAATGGCTGCTTCATCTGTTTCTGTAGTACTTTCTTCTCTCTTCCTTAAACTTTACAGG AAACCAACTTACGAGAGTTATGAACTGCCTGCCCGGAGCCAGATAGGACAGAAGAGTCCT TCAGAAATCAGCGTTCATGTTGGAATAGATGATACCTCAAGGAATTCTCCTAAACTGGGT TTGCTGGACCGGATTGTTAATTATAGCAGAGCCTCTATAAACTCACTACTGTCTGATAAA CGCTCCCTAAACAGTGTTGTTACCAGTGAACCTGACAAGCACTCACTCCTGGTGGGAGAC TTCAGGGAAGATGATGACACTGCATTATAAAAGGCCATGGAGAGTGCTGCCAGTTTAACT TGTCATGCACTGACACAGCATTCATGATGTTACCTTCACTTTTCAAAATATTGTAGAAGG ATTTTTCTCATGCTCTTATATTAGGGATTCTATTTGAGTTGCGTTTATCTGTTGGCAAAA ATATCTTTTTCAAGGCATCAGCTCTGAACCTAGCTTTATTTAAACTGAATTTCCAGTATA TTTTTGTTTTCACTAACAACAGATAAGGTAGAGCAGTGAGGTTTACAACAAGCCCTACAA TTAGAGATTGCTGAACTGCTGCTAAAGTGATTTTTTTTTTATTTGACCAAAAAAAAAAAG GCCCAAGAAGAAGAAAATGAAAAATTTGAAGATTTGAGAGCATGAAGATATTCATGCTTT TGAACTCAAAATATTGAAGATACTCTCAAGCCTGTATCCCTGCCCACTGGGGAGCAATGA CTTTCAAAGCACTGTGTATAAAACATCTAGTTTTAGAAGGGAAACAGTTGAAACTGTTTA AAAATAGATGTGCCTTATTTATTGCAGGCTTTCTTTCCCCCATTCTCCCTGCATCCTTGT CCTTGCAGGTGCTTTTTTAGATGCTCCAATATGTCTTCTTTTGTTATTTTCTTTCGAGCT AACCAAGTTTAGGTGGTTTTTCATTGATTAAAAATAACTGACAACTGTTCTAATATTTTG CTCCTTTTTAAATTTTGTAGCTCAAAAGACCTTAAAGGTCTGTAGGGTTCCCTGCCTCCC ATCTTTCCACTGTTGTAAAAAGTATATCAAATTATTCCTTCAAGTTTCCTAGCTCTGTGC TCAGTTTCAGTTCACTCCTGCCAAGTTGGACTCTAAGTTATTCTTCATGTAGTCTGCTGA TCTCAGTCTGGAAACTTAACATTATGAGCCTTTTCTGCTCAAAAAATTTTCAAAGATTAA AACTATTATACATATACAGGTCATATAAAATTACCTGGATTCACTAAAAAAAAAAAAAAA AAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_000052 |
| Insert Size | 5600 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. This clone may be unstable or toxic at high copy number in common E. coli strain. We recommend using a lower copy number E. coli strain, such as CopyCutter strain (http://www.epibio.com/item.asp?ID=435) for transformation and plasmid preparation. Please be aware that the DNA yield could be low. Additional aliquots of this clone can be ordered from OriGene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000052.2, NP_000043.2 |
| RefSeq Size | 8028 bp |
| RefSeq ORF | 4503 bp |
| Locus ID | 538 |
| UniProt ID | Q04656 |
| Domains | E1-E2_ATPase, Hydrolase, HMA |
| Protein Families | Druggable Genome, Transmembrane |
| Gene Summary | This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome. Alternatively-spliced transcript variants have been observed. [provided by RefSeq, Aug 2013] Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Biased Agonism as a Novel Strategy To Harness the Proresolving Properties of Melanocortin Receptors without Eliciting Melanogenic Effects
,Montero-Melendez, T;Gobbetti, T;Cooray, SN;Jonassen, TE;Perretti, M;,
J. Immunol.
,PubMed ID 25725103
[ATP7A]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC224789 | ATP7A (Myc-DDK-tagged)-Human ATPase, Cu++ transporting, alpha polypeptide (ATP7A). Note: ORF is codon optimized |
CNY 15,392.00 |
|
| RC224789L3 | Lenti ORF clone of Human ATPase, Cu++ transporting, alpha polypeptide (ATP7A), Myc-DDK-tagged. Note: ORF is codon optimized |
CNY 16,910.00 |
|
| RG224789 | ATP7A (tGFP-tagged) - Human ATPase, Cu++ transporting, alpha polypeptide (ATP7A). Note: ORF is codon optimized |
CNY 16,992.00 |
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