IRE1 (ERN2) (NM_033266) Human Untagged Clone

CAT#: SC308731

ERN2 (untagged)-Human endoplasmic reticulum to nucleus signaling 2 (ERN2)



  "NM_033266" in other vectors (7)

CNY 7,144.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (4)
Rabbit Polyclonal Anti-ERN2 Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms hIRE2p; IRE1-BETA; IRE1b; IRE2p
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF sequence for NM_033266 edited
GAGTGTGATGAGAAGGGCGGGGATCGGCGAGGACTCCAGGCTGGGGTTGCAGGCCCAGCC
AGGGGCGGAGCCTTCTCCGGGTCGGGCGGGGACAGAGCGCTCCCTTGGAGGCGCCCAGGG
ACCTGGCCAGCCGTGCAGCTGCCCAGGCGCTATGGCGAGTGCGGTCAGGGGGTCGAGGCC
GTGGCCCCGGCTGGGGCTCCAGCTCCAGTTCGCGGCGCTGCTGCTCGGGACGCTGAGTCC
ACAGGTTCATACTCTCAGGCCAGAGAACCTCCTGCTGGTGTCCACCTTGGATGGAAGTCT
CCACGCACTAAGCAAGCAGACAGGGGACCTGAAGTGGACTCTGAGGGATGATCCCGTCAT
CGAAGGACCAATGTACGTCACAGAAATGGCCTTTCTCTCTGACCCAGCAGATGGCAGCCT
GTACATCTTGGGGACCCAAAAACAACAGGGATTAATGAAACTGCCATTCACCATCCCTGA
GCTGGTTCATGCCTCTCCCTGCCGCAGCTCTGATGGGGTCTTCTACACAGGCCGGAAGCA
GGATGCCTGGTTTGTGGTGGACCCTGAGTCAGGGGAGACCCAGATGACACTGACCACAGA
GGGTCCCTCCACCCCCCGCCTCTACATTGGCCGAACACAGTATACGGTCACCATGCATGA
CCCAAGAGCCCCAGCCCTGCGCTGGAACACCACCTACCGCCGCTACTCAGCGCCCCCCAT
GGATGGCTCACCTGGGAAATACATGAGCCACCTGGCGTCCTGCGGGATGGGCCTGCTGCT
CACTGTGGACCCAGGAAGCGGGACGGTGCTGTGGACACAGGACCTGGGCGTGCCTGTGAT
GGGCGTCTACACCTGGCACCAGGACGGCCTGCGCCAGCTGCCGCATCTCACGCTGGCTCG
AGACACTCTGCATTTCCTCGCCCTCCGCTGGGGCCACATCCGACTGCCTGCCTCAGGCCC
CCGGGACACAGCCACCCTCTTCTCTACCTTGGACACCCAGCTGCTAATGACGCTGTATGT
GGGGAAGGATGAAACTGGCTTCTATGTCTCTAAAGCACTGGTCCACACAGGAGTGGCCCT
GATGCCTCGTGGACTGACCCTGGCCCCCGCAGATGGCCCCACCACAGATGAGGTGACACT
CCAAGTCTCAGGAGAGCGAGAGGGCTCACCCAGCACTGCTGTTAGATACCCCTCAGGCAG
TGTGGCCCTCCCAAGCCAGTGGCTGCTCATTGGACACCACGAGCTACCCCCAGTCCTGCA
CACCACCATGCTGAGGGTCCATCCCACCCTGGGGAGTGGAACTGCAGAGACAAGACCTCC
AGAGAATACCCAGGCCCCAGCCTTCTTCTTGGAGCTATTGAGCCTGAGCCGAGAGAAACT
TTGGGACTCCGAGCTGCATCCAGAAGAAAAAACTCCAGACTCTTACTTGGGGCTGGGACC
CCAAGACCTGCTGGCAGCTAGCCTCACTGCTGTCCTCCTGGGAGGGTGGATTCTCTTTGT
GATGAGGCAGCAACAGCCGCAGGTGGTGGAGAAGCAGCAGGAGACCCCCCTGGCACCTGC
AGACTTTGCTCACATCTCCCAGGATGCCCAGTCCCTGCACTCGGGGGCCAGCCGGAGGAG
CCAGAAGAGGCTTCAGAGTCCCTCAAAGCAAGCCCAGCCACTCGACGACCCTGAAGCTGA
GCAACTCACCGTAGTGGGGAAGATTTCCTTCAATCCCAAGGACGTGCTGGGCCGCGGGGC
AGGCGGGACTTTCGTTTTCCGGGGACAGTTTGAGGGACGGGCAGTGGCTGTCAAGCGGCT
CCTCCGCGAGTGCTTTGGCCTGGTTCGGCGGGAAGTTCAACTGCTGCAGGAGTCTGACAG
GCACCCCAACGTGCTCCGCTACTTCTGCACCGAGCGGGGACCCCAGTTCCACTACATTGC
CCTGGAGCTCTGCCGGGCCTCCTTGCAGGAGTACGTAGAAAACCCGGACCTGGATCGCGG
GGGTCTGGAGCCCGAGGTCGTGCTGCAGCAGCTGATGTCTGGCCTGGCCCACCTGCACTC
TTTACACATAGTGCACCGGGACCTGAAGCCAGGAAATATTCTCATCACCGGGCCTGACAG
CCAGGGCCTGGGCAGAGTGGTGCTCTCAGACTTCGGCCTCTGCAAGAAGCTGCCTGCTGG
CCGCTGTAGCTTCAGCCTCCACTCCGGCATCCCCGGCACGGAAGGCTGGATGGCGCCCGA
GCTTCTGCAGCTCCTGCCACCAGACAGTCCTACCAGCGCTGTGGACATCTTCTCTGCAGG
CTGCGTGTTCTACTACGTGCTTTCTGGTGGCAGCCACCCCTTTGGAGACAGTCTTTATCG
CCAGGCAAACATCCTCACAGGGGCTCCCTGTCTGGCTCACCTGGAGGAAGAGGTCCACGA
CAAGGTGGTTGCCCGGGACCTGGTTGGAGCCATGTTGAGCCCACTGCCGCAGCCACGCCC
CTCTGCCCCCCAGGTGCTGGCCCACCCCTTCTTTTGGAGCAGAGCCAAGCAACTCCAGTT
CTTCCAGGACGTCAGTGACTGGCTGGAGAAGGAGTCCGAGCAGGAGCCCCTGGTGAGGGC
ACTGGAGGCGGGAGGCTGCGCAGTGGTCCGGGACAACTGGCACGAGCACATCTCCATGCC
GCTGCAGACAGATCTGAGAAAGTTCCGGTCCTATAAGGGGACATCAGTGCGAGACCTGCT
CCGTGCTGTGAGGAACAAGAAGCACCACTACAGGGAGCTCCCAGTTGAGGTGCGACAGGC
ACTCGGCCAAGTCCCTGATGGCTTCGTCCAGTACTTCACAAACCGCTTCCCACGGCTGCT
CCTCCACACGCACCGAGCCATGAGGAGCTGCGCCTCTGAGAGCCTCTTCCTGCCCTACTA
CCCGCCAGACTCAGAGGCCAGGAGGCCATGCCCTGGGGCCACAGGGAGGTGAGGTGGGCT
GGATGCCACACAGATGGTCTCCGTGCTGGCTCACTGAAGAGCTGAGCCTGTGGCTGGCCT
CAGAATCAGGCTGGGTGCAGTGGCTCA
>OriGene 5' read for NM_033266 unedited
NAAGTTCACTATTGTATACGACTCACTATAGGCGGCCGCGACATCGCCCNGGTGTGATGA
GAAGGGCGGGGATCGGCGAGGACTCCAGGCTGGGGTTGCAGGCCCAGCCAGGGGCGGAGC
CTTCTCCGGGTCGGGCGGGGACAGAGCGCTCCCTTGGAGGCGCCCAGGGACCTGGCCAGC
CGTGCAGCTGCCCAGGCGCTATGGCGAGTGCGGTCAGGGGGTCGAGGCCGTGGCCCCGGC
TGGGGCTCCAGCTCCAGTTCGCGGCGCTGCTGCTCGGGACGCTGAGTCCACAGGTTCATA
CTCTCAGGCCAGAGAACCTCCTGCTGGTGTCCACCTTGGATGGAAGTCTCCACGCACTAA
GCAAGCAGACAGGGGACCTGAAGTGGACTCTGAGGGATGATCCCGTCATCGAAGGACCAA
TGTACGTCACAGAAATGGCCTTTCTCTCTGACCCAGCAGATGGCAGCCTGTACATCTTGG
GGACCCAAAAACAACAGGGATTAATGAAACTGCCATTCACCATCCCTGAGCTGGTTCATG
CCTCTCCCTGCCGCAGCTCTGATGGGGTCTTCTACACAGGCCGGAAGCAGGATGCCTGGT
TTGTGGTGGACCCTGAGTCAGGGGAGACCCAGATGACACTGACCACAGAGGGTCCCTCCA
CCCCCCGCCTCTACATTGGCCGAACACAGTATACGGTCACCATGCATGACCCAAGAGCCC
CAGCCCTGCGCTGGAACACCACCTACCGCCGCTACTCAGCGCCCCCCATGGATGGCTCAC
CTGGGAAATACATGAGCCACCTGGCGTCCTGCGGGATGGGCCTGCTGCTCACTGTGGACC
CAGGAGCGGGACGGTGCTGTTNACACAAGACCTGGGGCTTGCCTGTGATGGGCG
Restriction Sites Please inquire     
ACCN NM_033266
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation There is 1 nucleotide difference between the OriGene clone and the NCBI reference ORF. OriGene considers this to be a polymorphism and to reflect the natural differences between individuals. This results in the conservative substitution of 1 amino acid.
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_033266.2, NP_150296.2
RefSeq Size 3549 bp
RefSeq ORF 2925 bp
Locus ID 10595
UniProt ID Q76MJ5
Protein Families Druggable Genome, Protein Kinase
Gene Summary Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins.[UniProtKB/Swiss-Prot Function]
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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