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IRE1 (ERN2) (NM_033266) Human Untagged Clone
CAT＃: SC308731
ERN2 (untagged)-Human endoplasmic reticulum to nucleus signaling 2 (ERN2)
CNY 7,144.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | hIRE2p; IRE1-BETA; IRE1b; IRE2p |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_033266 edited
GAGTGTGATGAGAAGGGCGGGGATCGGCGAGGACTCCAGGCTGGGGTTGCAGGCCCAGCC AGGGGCGGAGCCTTCTCCGGGTCGGGCGGGGACAGAGCGCTCCCTTGGAGGCGCCCAGGG ACCTGGCCAGCCGTGCAGCTGCCCAGGCGCTATGGCGAGTGCGGTCAGGGGGTCGAGGCC GTGGCCCCGGCTGGGGCTCCAGCTCCAGTTCGCGGCGCTGCTGCTCGGGACGCTGAGTCC ACAGGTTCATACTCTCAGGCCAGAGAACCTCCTGCTGGTGTCCACCTTGGATGGAAGTCT CCACGCACTAAGCAAGCAGACAGGGGACCTGAAGTGGACTCTGAGGGATGATCCCGTCAT CGAAGGACCAATGTACGTCACAGAAATGGCCTTTCTCTCTGACCCAGCAGATGGCAGCCT GTACATCTTGGGGACCCAAAAACAACAGGGATTAATGAAACTGCCATTCACCATCCCTGA GCTGGTTCATGCCTCTCCCTGCCGCAGCTCTGATGGGGTCTTCTACACAGGCCGGAAGCA GGATGCCTGGTTTGTGGTGGACCCTGAGTCAGGGGAGACCCAGATGACACTGACCACAGA GGGTCCCTCCACCCCCCGCCTCTACATTGGCCGAACACAGTATACGGTCACCATGCATGA CCCAAGAGCCCCAGCCCTGCGCTGGAACACCACCTACCGCCGCTACTCAGCGCCCCCCAT GGATGGCTCACCTGGGAAATACATGAGCCACCTGGCGTCCTGCGGGATGGGCCTGCTGCT CACTGTGGACCCAGGAAGCGGGACGGTGCTGTGGACACAGGACCTGGGCGTGCCTGTGAT GGGCGTCTACACCTGGCACCAGGACGGCCTGCGCCAGCTGCCGCATCTCACGCTGGCTCG AGACACTCTGCATTTCCTCGCCCTCCGCTGGGGCCACATCCGACTGCCTGCCTCAGGCCC CCGGGACACAGCCACCCTCTTCTCTACCTTGGACACCCAGCTGCTAATGACGCTGTATGT GGGGAAGGATGAAACTGGCTTCTATGTCTCTAAAGCACTGGTCCACACAGGAGTGGCCCT GATGCCTCGTGGACTGACCCTGGCCCCCGCAGATGGCCCCACCACAGATGAGGTGACACT CCAAGTCTCAGGAGAGCGAGAGGGCTCACCCAGCACTGCTGTTAGATACCCCTCAGGCAG TGTGGCCCTCCCAAGCCAGTGGCTGCTCATTGGACACCACGAGCTACCCCCAGTCCTGCA CACCACCATGCTGAGGGTCCATCCCACCCTGGGGAGTGGAACTGCAGAGACAAGACCTCC AGAGAATACCCAGGCCCCAGCCTTCTTCTTGGAGCTATTGAGCCTGAGCCGAGAGAAACT TTGGGACTCCGAGCTGCATCCAGAAGAAAAAACTCCAGACTCTTACTTGGGGCTGGGACC CCAAGACCTGCTGGCAGCTAGCCTCACTGCTGTCCTCCTGGGAGGGTGGATTCTCTTTGT GATGAGGCAGCAACAGCCGCAGGTGGTGGAGAAGCAGCAGGAGACCCCCCTGGCACCTGC AGACTTTGCTCACATCTCCCAGGATGCCCAGTCCCTGCACTCGGGGGCCAGCCGGAGGAG CCAGAAGAGGCTTCAGAGTCCCTCAAAGCAAGCCCAGCCACTCGACGACCCTGAAGCTGA GCAACTCACCGTAGTGGGGAAGATTTCCTTCAATCCCAAGGACGTGCTGGGCCGCGGGGC AGGCGGGACTTTCGTTTTCCGGGGACAGTTTGAGGGACGGGCAGTGGCTGTCAAGCGGCT CCTCCGCGAGTGCTTTGGCCTGGTTCGGCGGGAAGTTCAACTGCTGCAGGAGTCTGACAG GCACCCCAACGTGCTCCGCTACTTCTGCACCGAGCGGGGACCCCAGTTCCACTACATTGC CCTGGAGCTCTGCCGGGCCTCCTTGCAGGAGTACGTAGAAAACCCGGACCTGGATCGCGG GGGTCTGGAGCCCGAGGTCGTGCTGCAGCAGCTGATGTCTGGCCTGGCCCACCTGCACTC TTTACACATAGTGCACCGGGACCTGAAGCCAGGAAATATTCTCATCACCGGGCCTGACAG CCAGGGCCTGGGCAGAGTGGTGCTCTCAGACTTCGGCCTCTGCAAGAAGCTGCCTGCTGG CCGCTGTAGCTTCAGCCTCCACTCCGGCATCCCCGGCACGGAAGGCTGGATGGCGCCCGA GCTTCTGCAGCTCCTGCCACCAGACAGTCCTACCAGCGCTGTGGACATCTTCTCTGCAGG CTGCGTGTTCTACTACGTGCTTTCTGGTGGCAGCCACCCCTTTGGAGACAGTCTTTATCG CCAGGCAAACATCCTCACAGGGGCTCCCTGTCTGGCTCACCTGGAGGAAGAGGTCCACGA CAAGGTGGTTGCCCGGGACCTGGTTGGAGCCATGTTGAGCCCACTGCCGCAGCCACGCCC CTCTGCCCCCCAGGTGCTGGCCCACCCCTTCTTTTGGAGCAGAGCCAAGCAACTCCAGTT CTTCCAGGACGTCAGTGACTGGCTGGAGAAGGAGTCCGAGCAGGAGCCCCTGGTGAGGGC ACTGGAGGCGGGAGGCTGCGCAGTGGTCCGGGACAACTGGCACGAGCACATCTCCATGCC GCTGCAGACAGATCTGAGAAAGTTCCGGTCCTATAAGGGGACATCAGTGCGAGACCTGCT CCGTGCTGTGAGGAACAAGAAGCACCACTACAGGGAGCTCCCAGTTGAGGTGCGACAGGC ACTCGGCCAAGTCCCTGATGGCTTCGTCCAGTACTTCACAAACCGCTTCCCACGGCTGCT CCTCCACACGCACCGAGCCATGAGGAGCTGCGCCTCTGAGAGCCTCTTCCTGCCCTACTA CCCGCCAGACTCAGAGGCCAGGAGGCCATGCCCTGGGGCCACAGGGAGGTGAGGTGGGCT GGATGCCACACAGATGGTCTCCGTGCTGGCTCACTGAAGAGCTGAGCCTGTGGCTGGCCT CAGAATCAGGCTGGGTGCAGTGGCTCA >OriGene 5' read for NM_033266 unedited
NAAGTTCACTATTGTATACGACTCACTATAGGCGGCCGCGACATCGCCCNGGTGTGATGA GAAGGGCGGGGATCGGCGAGGACTCCAGGCTGGGGTTGCAGGCCCAGCCAGGGGCGGAGC CTTCTCCGGGTCGGGCGGGGACAGAGCGCTCCCTTGGAGGCGCCCAGGGACCTGGCCAGC CGTGCAGCTGCCCAGGCGCTATGGCGAGTGCGGTCAGGGGGTCGAGGCCGTGGCCCCGGC TGGGGCTCCAGCTCCAGTTCGCGGCGCTGCTGCTCGGGACGCTGAGTCCACAGGTTCATA CTCTCAGGCCAGAGAACCTCCTGCTGGTGTCCACCTTGGATGGAAGTCTCCACGCACTAA GCAAGCAGACAGGGGACCTGAAGTGGACTCTGAGGGATGATCCCGTCATCGAAGGACCAA TGTACGTCACAGAAATGGCCTTTCTCTCTGACCCAGCAGATGGCAGCCTGTACATCTTGG GGACCCAAAAACAACAGGGATTAATGAAACTGCCATTCACCATCCCTGAGCTGGTTCATG CCTCTCCCTGCCGCAGCTCTGATGGGGTCTTCTACACAGGCCGGAAGCAGGATGCCTGGT TTGTGGTGGACCCTGAGTCAGGGGAGACCCAGATGACACTGACCACAGAGGGTCCCTCCA CCCCCCGCCTCTACATTGGCCGAACACAGTATACGGTCACCATGCATGACCCAAGAGCCC CAGCCCTGCGCTGGAACACCACCTACCGCCGCTACTCAGCGCCCCCCATGGATGGCTCAC CTGGGAAATACATGAGCCACCTGGCGTCCTGCGGGATGGGCCTGCTGCTCACTGTGGACC CAGGAGCGGGACGGTGCTGTTNACACAAGACCTGGGGCTTGCCTGTGATGGGCG |
| Restriction Sites | Please inquire |
| ACCN | NM_033266 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | There is 1 nucleotide difference between the OriGene clone and the NCBI reference ORF. OriGene considers this to be a polymorphism and to reflect the natural differences between individuals. This results in the conservative substitution of 1 amino acid. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_033266.2, NP_150296.2 |
| RefSeq Size | 3549 bp |
| RefSeq ORF | 2925 bp |
| Locus ID | 10595 |
| UniProt ID | Q76MJ5 |
| Protein Families | Druggable Genome, Protein Kinase |
| Gene Summary | Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC224780 | ERN2 (Myc-DDK-tagged)-Human endoplasmic reticulum to nucleus signaling 2 (ERN2) |
CNY 7,136.00 |
|
| RC224780L1 | Lenti ORF clone of Human endoplasmic reticulum to nucleus signaling 2 (ERN2), Myc-DDK-tagged |
CNY 9,536.00 |
|
| RC224780L2 | Lenti ORF clone of Human endoplasmic reticulum to nucleus signaling 2 (ERN2), mGFP tagged |
CNY 9,030.00 |
|
| RC224780L3 | Lenti ORF clone of Human endoplasmic reticulum to nucleus signaling 2 (ERN2), Myc-DDK-tagged |
CNY 9,030.00 |
|
| RC224780L4 | Lenti ORF clone of Human endoplasmic reticulum to nucleus signaling 2 (ERN2), mGFP tagged |
CNY 9,030.00 |
|
| RG224780 | ERN2 (tGFP-tagged) - Human endoplasmic reticulum to nucleus signaling 2 (ERN2) |
CNY 8,736.00 |
|
| SC323535 | ERN2 (untagged)-Kinase deficient mutant (K596M) of Human endoplasmic reticulum to nucleus signaling 2 (ERN2) |
CNY 7,144.00 |
