Dopamine D2 Receptor (DRD2) (NM_016574) Human Untagged Clone
CAT#: SC308892
DRD2 (untagged)-Human dopamine receptor D2 (DRD2), transcript variant 2
CNY 3,656.00
CNY 6,650.00
Cited in 1 publication. |
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | D2DR; D2R |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF sequence for NM_016574 edited
GGGCGGCCGCGAATTCGGCACGAGCCGCCCCGCCGCGGCCCGTCCACTGCTCCCCGCGGG CCAGAGCCGGCCGAGCTGCTGCCCGCCGGGGCTCTGAACGGCGCGGCGGGGCCGGGAGCC AGGGACCGGCCGAGGAGAGTGGCGGCCCCGGACGGCTGCCGGAGGGGCGGCCGCGCGTGG ATGCGGCGGGAGCTGGAAGCCTCAAGCAGCCGGCGCCGTCTCTGCCCCGGGGCGCCCTAT GGCTTGAAGAGCCTGGCCACCCAGTGGCTCCACCGCCCTGATGGATCCACTGAATCTGTC CTGGTATGATGATGATCTGGAGAGGCAGAACTGGAGCCGGCCCTTCAACGGGTCAGACGG GAAGGCGGACAGACCCCACTACAACTACTATGCCACACTGCTCACCCTGCTCATCGCTGT CATCGTCTTCGGCAACGTGCTGGTGTGCATGGCTGTGTCCCGCGAGAAGGCGCTGCAGAC CACCACCAACTACCTGATCGTCAGCCTCGCAGTGGCCGACCTCCTCGTCGCCACACTGGT CATGCCCTGGGTTGTCTACCTGGAGGTGGTAGGTGAGTGGAAATTCAGCAGGATTCACTG TGACATCTTCGTCACTCTGGACGTCATGATGTGCACGGCGAGCATCCTGAACTTGTGTGC CATCAGCATCGACAGGTACACAGCTGTGGCCATGCCCATGCTGTACAATACGCGCTACAG CTCCAAGCGCCGGGTCACCGTCATGATCTCCATCGTCTGGGTCCTGTCCTTCACCATCTC CTGCCCACTCCTCTTCGGACTCAATAACGCAGACCAGAACGAGTGCATCATTGCCAACCC GGCCTTCGTGGTCTACTCCTCCATCGTCTCCTTCTACGTGCCCTTCATTGTCACCCTGCT GGTCTACATCAAGATCTACATTGTCCTCCGCAGACGCCGCAAGCGAGTCAACACCAAACG CAGCAGCCGAGCTTTCAGGGCCCACCTGAGGGCTCCACTAAAGGAGGCTGCCCGGCGAGC CCAGGAGCTGGAGATGGAGATGCTCTCCAGCACCAGCCCACCCGAGAGGACCCGGTACAG CCCCATCCCACCCAGCCACCACCAGCTGACTCTCCCCGACCCGTCCCACCACGGTCTCCA CAGCACTCCCGACAGCCCCGCCAAACCAGAGAAGAATGGGCATGCCAAAGACCACCCCAA GATTGCCAAGATCTTTGAGATCCAGACCATGCCCAATGGCAAAACCCGGACCTCCCTCAA GACCATGAGCCGTAGGAAGCTCTCCCAGCAGAAGGAGAAGAAAGCCACTCAGATGCTCGC CATTGTTCTCGGCGTGTTCATCATCTGCTGGCTGCCCTTCTTCATCACACACATCCTGAA CATACACTGTGACTGCAACATCCCGCCTGTCCTGTACAGCGCCTTCACGTGGCTGGGCTA TGTCAACAGCGCCGTGAACCCCATCATCTACACCACCTTCAACATTGAGTTCCGCAAGGC CTTCCTGAAGATCCTCCACTGCTGACTCTGCTGCCTGCCCGCACAGCAGCCTGCTTCCCA CCTCCCTGCCCAGGCCAGCCAGCCTCACCCTTGCGAACCGTGAGCAGGAAGGCCTGGGTG GATCGGCCTCCTCTTCACCCCGGCAGGCCCTGCAGTGTTCGCTTGGCTCCATGCTCCTCA CTGCCCGCACACCCTCACTCTGCCAGGGCAGTGCTAGTGAGCTGGGCATGGTACCAGCCC TGGGGCTGGGCCCCCCAGCTCAGGGGCAGCTCATAGAGTCCCCCCTCCCACCTCCAGTCC CCCTATCCTTGGCACCAAAGATGCAGCCGCCTTCCTTGACCTTCCTCTGGGGCTCTAGGG TTGCTGGAGCCTGAGTCAGGGCCCAGAGGCTGAGTTTTCTGTTTGTGGGGCTTGGCGTGG AGCAGGCGGTGGGGAGAGATGGACAGTTCACACCCTGCAAGGCCCACAGGAGGCAAGCAA GCTCTCTTGCCGAGGAGCCAGGCAACTTCAGTCCTGGGAGACCCATGTAAATACCAGACT GCAGGTTGGACCCCAGAGATTCCCAAGCCAAAAACCTTAGCTCCCTCCCGCACCCCGATG TGGACCTCTACTTTCCAGGCTAGTCCGGACCCACCTCACCCCGTTACAGCTCCCCAAGTG GTTTCCACATGCTCTGAGAAGAGGAGCCCTCATCTTGAAGGGCCCAGGAGGGTCTATGGG GAGAGGAACTCCTTGGCCTAGCCCACCCTTCTGCCTTCTGACGGCCCTGCAATGTATCCC TTCTCACAGCACATGCTGGCCAGCCTGGGGCCTGGCAGGGAGGTCAGGCCCTGGAACTCT ATCTGGGCCTGGGCTAGGGGACATCAGAGGTTCTTTGAGGGACTGCCTCTGCCACACTCT GACGCAAAACCACTTTCCTTTTCTATTCCTTCTGGCCTTTCCTCTCTCCTGTTTCCCTTC CCTTCCACTGCCTCTGCCTTAGAGGAGCCCACGGCTAAGAGGCTGCTGAAAACCATCTGG CCTGGCCTGGCCCTGCCCTGAGGAAGGAGGGGAAGCTGCAGCTTGGGAGAGCCCCTGGGG CCTAGACTCTGTAACATCACTATCCATGCACCAAACTAATAAAACTTTGACGAGTCACCT CCAGGAAAAAAAAAAAAAAGGGAAAAAAAACTCGAC >OriGene 5' read for NM_016574 unedited
TTACATCGCCGACCCGTTGTCCCATTGGGCGGTAGGCGTGTGCGGTGGGCAGGTCTATAT AAGCAGAGCTCGTTTAGTGAACCGTCAGATTTTGTAATACGACTCACTATAGGGCGGCCG CGAATTCGGCACGAGCCGCCCCGCCGCGGCCCGTCCACTGCTCCCCGCGGGCCAGAGCCG GCCGAGCTGCTGCCCGCCGGGGCTCTGAACGGCGCGGCGGGGCCGGGAGCCAGGGACCGG CCGAGGAGAGTGGCGGCCCCGGACGGCTGCCGGAGGGGCGGCCGCGCGTGGATGCGGCGG GAGCTGGAAGCCTCAAGCAGCCGGCGCCGTCTCTGCCCCGGGGCGCCCTATGGCTTGAAG AGCCTGGCCACCCAGTGGCTCCACCGCCCTGATGGATCCACTGAATCTGTCCTGGTATGA TGATGATCTGGAGAGGCAGAACTGGAGCCGGCCCTTCAACGGGTCATACGGGAAGGCGGA CAGACCCCACTACAACTACTATGCCACACTGCTCACCCTGCTCATCGCTGTCATCGTCTT CGGCAACGTGCTGGTGTGCATGGCTGTGTCCCGCGAGGAGGCGCTGCAGACCACCACCAA CTACCTGATCGTCAGCCTCACAGTGGCCGACCTCCTCGTCGCCACACTGGTCATGCCCTG GGTTGTCTACCTGGAAGTGGTAAGTGAGTGGAAAATCAGCAGCATCACTGTGACATCTTC ATCACTCCGGGCGTCATGATGTGCACGGGCGAGCCTTCTGAACCTGTGGTGCCATAAGCA TCGAAGGTACCCAAATGGGGCCCATGCCCACTGCTGGAAATAACTCGCTAC >OriGene 3' read for NM_016574 unedited
NTGTTGGTGGCTNCTTCNGATTTTATTAGTTTGGTGCATGGCTAGTGATGTTACAGTAGT CTAAGGCCCCAGGGGTCTCTCCCAAGCTGCAGCTTCCCCTCCTTCCTCAGGCAGGGCCAG GCCAGGCCAGATGGTTTTCAGCAGCCTCTTAGCCGTGGGCTCCTCTAAGGCAGAGGCAGT GGAAGGGAAGGGAAACAGGAGAGAGGAAAGGCCAGAAGGAATAGAAAAGGAAAGTGGTTT TGCGTCAGAGTGTGGCAGAGGCAGTCCCTCAAAGAACCTCTGATGTCCCCTAGCCCAGGC CCAGATAGAGTTCCAGGGCCTGACCTCCCTGCCAGGCCCCAGGCTGGCCAGCATGTGCTG TGAGAAGGGATACATTGCAGGGCCGTCAGAAGGCAGAAGGGTGGGCTAGGCCAAGGAGTT CCTCTCCCCATAGACCCTCCTGGGCCCTTCAAGATGAGGGCTCCTCTTCTCAGAGCATGT GGAAACCACTTGGGGAGCTGTAACGGGGTGAGGTGGGTCCGGACTAGCCTGGAAAGTAGA GGTCCACATCGGGGTGCGGGAGGGAGCTAAGGTTTTTGGCTTGGGAATCTCTGGGGTCCA ACCTGCAGTCTGGTATTTACATGGGTCTCCCANGACTGAAGTTGCCTGGCTCCTCGGCAA GAGAGCTTGCTTGCCTCCTGTGGGCCTTGCAAGGTGTGAACTGTCCATCTCTTCCCACCG CCTGCTTCAAGGCCAGGCCCACAAACAGAAAACTCAGCCTCTTGGGCCCTGACTCCAGCT CCAGCAACCCCTAGAGCCCCCAAAGGAAGGTCAAGGAAAGGCGGCTTGCTCTTTGGTGCC CAGGGATAGGGGGACTGGAGGTGGGAAGGGGGGACTTTATAAGCTGCCCCTGGACTGGGG GGGCCCAGCCCCAGGGCCTGC |
Restriction Sites | Please inquire |
ACCN | NM_016574 |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_016574.2, NP_057658.2 |
RefSeq Size | 2556 bp |
RefSeq ORF | 1245 bp |
Locus ID | 1813 |
UniProt ID | P14416 |
Protein Families | Druggable Genome, GPCR, Transmembrane |
Protein Pathways | Gap junction, Neuroactive ligand-receptor interaction |
Gene Summary | This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) lacks an internal exon, as compared to variant 1, but maintains the same reading frame. It encodes an isoform (short), which is 29 aa shorter than isoform long. |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
---|
Aminobutyric Acid Type B (GABAB) Receptor Expression Is Needed for Inhibition of N-type (Cav2.2) Calcium Channels by Analgesic a-Conotoxins
,Hartmut Cuny, Andrew de Faoite, Thuan G. Huynh, Takahiro Yasuda, Géza Berecki, and David J. Adams,
J. Biol. Chem., Jul 2012; 287: 23948 - 23957.
[DRD2]
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SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC213065 | DRD2 (Myc-DDK-tagged)-Human dopamine receptor D2 (DRD2), transcript variant 2 |
CNY 3,656.00 |
|
RC213065L1 | Lenti ORF clone of Human dopamine receptor D2 (DRD2), transcript variant 2, Myc-DDK-tagged |
CNY 6,056.00 |
|
RC213065L2 | Lenti ORF clone of Human dopamine receptor D2 (DRD2), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
RC213065L3 | Lenti ORF clone of Human dopamine receptor D2 (DRD2), transcript variant 2, Myc-DDK-tagged |
CNY 6,056.00 |
|
RC213065L4 | Lenti ORF clone of Human dopamine receptor D2 (DRD2), transcript variant 2, mGFP tagged |
CNY 6,056.00 |
|
RG213065 | DRD2 (tGFP-tagged) - Human dopamine receptor D2 (DRD2), transcript variant 2 |
CNY 5,256.00 |
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