PI 3 Kinase Class 2A (PIK3C2A) (NM_002645) Human Untagged Clone
CAT#: SC309022
PIK3C2A (untagged)-Human phosphoinositide-3-kinase, class 2, alpha polypeptide (PIK3C2A)
CNY 11,344.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | CPK; OCSKD; PI3-K-C2(ALPHA); PI3-K-C2A; PI3K-C2-alpha; PI3K-C2alpha |
Vector | pCMV6-XL6 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene sequence for NM_002645 edited
GGCCTTGCTATTTTGGAAGCTACAAGAAAAAAATAGAGGAAGGAAGGTTTGGTCTTTTTA GTGGACATGGCTCAGATATCTAGCAACAGCGGATTTAAAGAATGTCCATCTTCACATCCG GAACCAACAAGAGCAAAAGATGTGGACAAAGAAGAAGCATTACAGATGGAAGCAGAGGCT TTAGCAAAACTGCAAAAGGATAGACAAGTGACTGACAATCAGAGAGGCTTTGAGTTGTCA AGCAGCACCAGAAAAAAAGCACAGGTTTATAACAAGCAGGATTATGATCTCATGGTGTTT CCTGAATCAGATTCCCAAAAAAGAGCATTAGATATTGATGTAGAAAAGCTCACCCAAGCT GAACTTGAGAAACTATTGCTGGATGACAGTTTCGAGACTAAAAAAACACCTGTATTACCA GTTACTCCTATTCTGAGCCCTTCCTTTTCAGCACAGCTCTATTTTAGACCTACTATTCAG AGAGGACAGTGGCCACCTGGATTACCTGGGCCTTCCACTTATGCTTTACCTTCTATTTAT CCTTCTACTTACAGTAAACAGGCTGCATTCCAAAATGGCTTCAATCCAAGAATGCCCACT TTTCCATCTACAGAACCTATATATTTAAGTCTTCCGGGACAATCTCCATATTTCTCATAT CCTTTGACACCTGCCACACCCTTTCATCCACAAGGAAGCTTACCTATCTATCGTCCAGTA GTCAGTACTGACATGGCAAAACTATTTGACAAAATAGCTAGTACATCAGAATTTTTAAAA AATGGGAAAGCAAGGACTGATTTGGAGATAACAGATTCAAAAGTCAGCAATCTACAGGTA TCTCCAAAGTCTGAGGATATCAGTAAATTTGACTGGTTAGACTTGGATCCTCTAAGTAAG CCTAAGGTGGATAATGTGGAGGTATTAGACCATGAGGAAGAGAAAAATGTTTCAAGTTTG CTAGCAAAGGATCCTTGGGATGCTGTTCTTCTTGAAGAGAGATCGACAGCAAATTGTCAT CTTGAAAGAAAGGTGAATGGAAAATCCCTTTCTGTGGCAACTGTTACAAGAAGCCAGTCT TTAAATATTCGAACAACTCAGCTTGCAAAAGCCCAGGGCCATATATCTCAGAAAGACCCA AATGGGACCAGTAGTTTGCCAACTGGAAGTTCTCTTCTTCAAGAAGTTGAAGTACAGAAT GAGGAGATGGCAGCTTTTTGTCGATCCATTACAAAATTGAAGACCAAATTTCCATATACC AATCACCGCACAAACCCAGGCTATTTGTTAAGTCCAGTCACAGCGCAAAGAAACATATGC GGAGAAAATGCTAGTGTGAAGGTCTCCATTGACATTGAAGGATTTCAGCTACCAGTTACT TTTACGTGTGATGTGAGTTCTACTGTAGAAATCATTATAATGCAAGCCCTTTGCTGGGTA CATGATGACTTGAATCAAGTAGATGTTGGCAGCTATGTTCTAAAAGTTTGTGGTCAAGAG GAAGTGCTGCAGAATAATCATTGCCTTGGAAGTCATGAGCATATTCAAAACTGTCGAAAA TGGGACACAGAAATTAGACTACAACTCTTGACCTTCAGTGCAATGTGTCAAAATCTGGCC CGAACAGCAGAAGATGATGAAACACCCGTGGATTTAAACAAACACCTGTATCAAATAGAA AAACCTTGCAAAGAAGCCATGACGAGACACCCTGTTGAAGAACTCTTAGATTCTTATCAC AACCAAGTAGAACTGGCTCTTCAAATTGAAAACCAACACCGAGCAGTAGATCAAGTAATT AAAGCTGTAAGAAAAATCTGTAGTGCTTTAGATGGTGTCGAGACTCTTGCCATTACAGAA TCAGTAAAGAAGCTAAAGAGAGCAGTTAATCTTCCAAGGAGTAAAACTGCTGATGTGACT TCTTTGTTTGGAGGAGAAGACACTAGCAGGAGTTCAACTAGGGGCTCACTTAATCCTGAA AATCCTGTTCAAGTAAGCATAAACCAATTAACTGCAGCAATTTATGATCTTCTCAGACTC CATGCAAATTCTGGTAGGAGTCCTACAGACTGTGCCCAAAGTAGCAAGAGTGTCAAGGAA GCATGGACTACAACAGAGCAGCTCCAGTTTACTATTTTTGCTGCTCATGGAATTTCAAGT AATTGGGTATCAAATTATGAAAAATACTACTTGATATGTTCACTGTCTCACAATGGAAAG GATCTTTTTAAACCTATTCAATCAAAGAAGGTTGGCACTTACAAGAATTTCTTCTATCTT ATTAAATGGGATGAACTAATCATTTTTCCTATCCAGATATCACAATTGCCATTAGAATCA GTTCTTCACCTTACTCTTTTTGGAATTTTAAATCAGAGCAGTGGAAGTTCCCCTGATTCT AATAAGCAGAGAAAGGGACCAGAAGCTTTGGGCAAAGTTTCTTTACCTCTTTTTGACTTT AAACGGTTTTTAACATGTGGAACTAAACTTCTATATCTTTGGACTTCATCACATACAAAT TCTGTTCCTGGAACAGTTACCAAAAAAGGATATGTCATGGAAAGAATAGTGCTACAGGTT GATTTTCCTTCTCCTGCATTTGATATTATTTATACAACTCCTCAAGTTGACAGAAGCATT ATACAGCAACATAACTTAGAAACACTAGAGAATGATATAAAAGGGAAACTTCTTGATATT CTTCATAAAGACTCATCACTTGGACTTTCTAAAGAAGATAAAGCTTTTTTATGGGAGAAA CGTTATTATTGCTTCAAACACCCAAATTGTCTTCCTAAAATATTAGCAAGCGCCCCAAAC TGGAAATGGGTTAATCTTGCCAAAACTTACTCATTGCTTCACCAGTGGCCTGCATTGTAC CCACTAATTGCATTGGAACTTCTTGATTCAAAATTTGCTGATCAGGAAGTAAGATCCCTA GCTGTGACCTGGATTGAGGCCATTAGTGATGATGAGCTAACAGATCTTCTTCCACAGTTT GTACAAGCTTTGAAATATGAAATTTACTTGAATAGTTCATTAGTGCAATTCCTTTTGTCC AGGGCATTGGGAAATATCCAGATAGCACACAATTTATATTGGCTTCTCAAAGATGCCCTG CATGATGTACAGTTTAGTACCCGATACGAACATGTTTTGGGTGCTCTCCTGTCAGTAGGA GGAAAACGACTTAGAGAAGAACTTCTAAAACAGACGAAACTTGTACAGCTTTTAGGAGGA GTAGCAGAAAAAGTAAGGCAGGCTAGTGGATCAGCCAGACAGGTTGTTCTCCAAAGAAGT ATGGAACGAGTACAGTCCTTTTTTCAGAAAAATAAATGCCGTCTCCCTCTCAAGCCAAGT CTAGTGGCAAAAGAATTAAATATTAAGTCGTGTTCCTTCTTCAGTTCTAATGCTGTCCCC CTAAAAGTCACAATGGTGAATGCTGACCCTATGGGAGAAGAAATTAATGTCATGTTTAAG GTTGGTGAAGATCTTCGGCAAGATATGTTAGCTTTACAGATGATAAAGATTATGGATAAG ATCTGGCTTAAAGAAGGACTAGATCTGAGGATGGTAATTTTCAAATGTCTCTCAACTGGC AGAGATCGAGGCATGGTGGAGCTGGTTCCTGCTTCCGATACCCTCAGGAAAATCCAAGTG GAATATGGTGTGACAGGATCCTTTAAAGATAAACCACTTGCAGAGTGGCTAAGGAAATAC AATCCCTCTGAAGAAGAATATGAAAAGGCTTCAGAGAACTTTATCTATTCCTGTGCTGGA TGCTGTGTAGCCACCTATGTTTTAGGCATCTGTGATCGACACAATGACAATATAATGCTT CGAAGCACGGGACACATGTTTCACATTGACTTTGGAAAGTTTTTGGGACATGCACAGATG TTTGGCAGCTTCAAAAGGGATCGGGCTCCTTTTGTGCTGACCTCTGATATGGCATATGTC ATTAATGGGGGTGAAAAGCCCACCATTCGTTTTCAGTTGTTTGTGGACCTCTGCTGTCAG GCCTACAACTTGATAAGAAAGCAGACAAACCTTTTTCTTAACCTCCTTTCACTGATGATT CCTTCAGGGTTACCAGAACTTACAAGTATTCAAGATTTGAAATACGTTAGAGATGCACTT CAACCCCAAACTACAGACGCAGAAGCTACAATTTTCTTTACTAGGCTTATTGAATCAAGT TTGGGAAGCATTGCCACAAAGTTTAACTTCTTCATTCACAACCTTGCTCAGCTTCGTTTT TCTGGTCTTCCTTCTAATGATGAGCCCATCCTTTCATTTTCACCTAAAACATACTCCTTT AGACAAGATGGTCGAATCAAGGAAGTCTCTGTTTTTACATATCATAAGAAATACAACCCA GATAAACATTATATTTATGTAGTCCGAATTTTGAGGGAAGGACAGATTGAACCATCATTT GTCTTCCGAACATTTGACGAATTTCAGGAACTTCACAATAAGCTCAGTATTATTTTTCCA CTTTGGAAGTTACCAGGCTTTCCTAATAGGATGGTTCTAGGAAGAACACACATAAAAGAT GTAGCAGCCAAAAGGAAAATTGAGTTAAACAGTTACTTACAGAGTTTGATGAATGCTTCA ACGGATGTAGCAGAGTGTGATCTTGTTTGTACTTTCTTCCACCCTTTACTTCGTGATGAG AAAGCTGAAGGGATAGCTAGGTCTGCAGATGCAGGTTCCTTCAGTCCTACTCCAGGCCAA ATAGGAGGAGCTGTGAAATTATCCATCTCTTACCGAAATGGTACTCTTTTCATCATGGTG ATGCATATCAAAGATCTTGTTACTGAAGATGGAGCTGACCCAAATCCATATGTCAAAACA TACCTACTTCCAGATAACCACAAAACATCCAAACGTAAAACCAAAATTTCACGAAAAACG AGGAATCCGACATTCAATGAAATGCTTGTATACAGTGGATATAGCAAAGAAACCCTAAGA CAGCGAGAACTTCAACTAAGTGTACTCAGTGCAGAATCTCTGCGGGAGAATTTTTTCTTG GGTGGAGTAACCCTGCCTTTGAAAGATTTCAACTTGAGCAAAGAGACGGTTAAATGGTAT CAGCTGACTGCGGCAACATACTTGTAAACTAGTGAATGTCTGAGCTTTGGAAGCATGAAC AGTTATAAACGTGCATGCATACATGCACACACACACAGAC |
Restriction Sites | Please inquire |
ACCN | NM_002645 |
Insert Size | 5200 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | The ORF of this clone is found to be a perfect match to NM_002645.1. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_002645.1, NP_002636.1 |
RefSeq Size | 5061 bp |
RefSeq ORF | 5061 bp |
Locus ID | 5286 |
UniProt ID | O00443 |
Domains | C2, PI3K_rbd, PI3_PI4_kinase, PI3Ka, PX, PI3K_C2 |
Protein Families | Druggable Genome |
Protein Pathways | Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system |
Gene Summary | The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. [provided by RefSeq, Jul 2008] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC222192 | PIK3C2A (Myc-DDK-tagged)-Human phosphoinositide-3-kinase, class 2, alpha polypeptide (PIK3C2A) |
CNY 11,336.00 |
|
RC222192L1 | Lenti ORF clone of Human phosphoinositide-3-kinase, class 2, alpha polypeptide (PIK3C2A), Myc-DDK-tagged |
CNY 13,736.00 |
|
RC222192L3 | Lenti ORF clone of Human phosphoinositide-3-kinase, class 2, alpha polypeptide (PIK3C2A), Myc-DDK-tagged |
CNY 18,720.00 |
|
RG222192 | PIK3C2A (tGFP-tagged) - Human phosphoinositide-3-kinase, class 2, alpha polypeptide (PIK3C2A) |
CNY 12,936.00 |
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