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IDN3 (NIPBL) (NM_133433) Human Untagged Clone
CAT＃: SC309093
NIPBL (untagged)-Human Nipped-B homolog (Drosophila) (NIPBL), transcript variant A
CNY 54,060.00
货期*
5周
规格
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CDLS; CDLS1; IDN3; IDN3-B; Scc2 |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_133433, the custom clone sequence may differ by one or more nucleotides
ATGAATGGGGATATGCCCCATGTCCCCATTACTACTCTTGCGGGGATTGCTAGTCTCACA GACCTCCTGAACCAGCTGCCTCTTCCATCTCCTTTACCTGCTACAACTACAAAGAGCCTT CTCTTTAATGCACGAATAGCAGAAGAGGTGAACTGCCTTTTGGCTTGTAGGGATGACAAT TTGGTTTCACAGCTTGTCCATAGCCTCAACCAGGTATCAACAGATCACATAGAGTTGAAA GATAACCTTGGCAGTGATGACCCAGAAGGTGACATACCAGTCTTGTTGCAGGCCGTCCTG GCAAGGAGTCCTAATGTTTTCAGGGAGAAAAGCATGCAGAACAGATATGTACAAAGTGGA ATGATGATGTCTCAGTATAAACTTTCTCAGAATTCCATGCACAGTAGTCCTGCATCTTCC AATTATCAACAAACCACTATCTCACATAGCCCCTCCAGCCGGTTTGTGCCACCACAGACA AGCTCTGGGAACAGATTTATGCCACAGCAAAATAGCCCAGTGCCTAGTCCATACGCCCCA CAAAGCCCTGCAGGATACATGCCATATTCCCATCCTTCAAGTTACACAACACATCCACAG ATGCAACAAGCATCGGTATCAAGTCCCATTGTTGCAGGTGGTTTGAGAAACATACATGAT AATAAAGTTTCTGGTCCGTTGTCTGGCAATTCAGCTAATCATCATGCTGATAATCCTAGA CATGGTTCAAGTGAGGACTACCTACACATGGTGCACAGGCTAAGTAGTGACGATGGAGAT TCTTCAACAATGAGGAATGCTGCATCTTTTCCCTTGAGATCTCCACAGCCAGTATGCTCC CCTGCTGGAAGTGAAGGAACTCCTAAAGGCTCAAGACCACCTTTAATCCTACAATCTCAG TCTCTACCTTGTTCATCACCTCGAGATGTTCCACCAGATATCTTGCTAGATTCTCCAGAA AGAAAACAAAAGAAGCAGAAGAAAATGAAATTAGGCAAGGATGAAAAAGAGCAGAGTGAG AAAGCGGCAATGTATGATATAATTAGTTCTCCATCCAAGGACTCTACTAAACTTACATTA AGACTTTCTCGTGTAAGGTCTTCAGACATGGACCAGCAAGAGGATATGATTTCTGGTGTG GAAAATAGCAATGTTTCAGAAAATGATATTCCTTTTAATGTGCAGTACCCAGGACAGACT TCAAAAACACCCATTACTCCACAAGATATAAACCGCCCACTAAATGCTGCTCAATGTTTG TCGCAGCAAGAACAAACAGCATTCCTTCCAGCAAATCAAGTGCCTGTTTTACAACAGAAC ACTTCAGTTGCTGCAAAACAACCCCAGACTTCTGTGGTACAGAATCAACAACAGATATCA CAACAGGGACCTATATATGATGAAGTGGAATTGGATGCATTGGCTGAAATTGAGCGAATA GAGAGAGAATCAGCTATTGAAAGGGAGCGCTTCTCAAAAGAAGTTCAAGATAAAGATAAG CCTTTGAAAAAAAGAAAACAAGATTCTTACCCACAGGAGGCTGGGGGTGCTACAGGAGGT AATAGACCAGCTTCTCAGGAGACGGGTTCTACGGGAAATGGGTCAAGGCCAGCATTAATG GTTAGCATTGATCTTCATCAGGCAGGAAGAGTGGACTCTCAGGCTTCTATAACTCAGGAT TCAGACTCCATAAAAAAGCCTGAAGAAATCAAACAATGTAATGATGCACCTGTTTCTGTT CTTCAGGAAGATATTGTTGGAAGTCTTAAATCTACACCAGAAAACCATCCTGAGACACCT AAAAAAAAGTCTGATCCTGAGCTTTCAAAGAGTGAAATGAAACAAAGTGAAAGTAGATTA GCAGAATCTAAACCAAATGAAAACCGATTGGTGGAGACAAAATCAAGTGAAAATAAGTTA GAAACTAAAGTTGAGACCCAAACAGAAGAACTTAAACAGAATGAGAGCAGAACAACTGAA TGCAAACAAAACGAGAGCACCATAGTTGAGCCTAAACAAAATGAAAATAGACTGTCTGAC ACAAAACCAAATGACAACAAACAAAATAATGGCAGATCAGAAACAACAAAATCAAGGCCT GAAACCCCAAAGCAAAAGGGTGAAAGCCGGCCTGAGACTCCAAAACAAAAGAGTGATGGG CATCCTGAAACCCCAAAACAGAAGGGTGATGGAAGGCCTGAAACTCCAAAGCAAAAAGGT GAGAGCCGCCCTGAAACTCCAAAGCAAAAAAATGAAGGGCGACCTGAAACACCAAAACAC AGGCATGACAATAGGAGGGATTCTGGAAAGCCATCTACAGAGAAAAAACCTGAAGTGTCT AAACATAAACAAGATACTAAATCTGACTCACCTCGGTTAAAATCAGAACGAGCTGAAGCC TTAAAGCAGAGACCTGATGGGCGATCTGTTTCTGAGTCACTAAGACGTGACCATGATAAT AAACAAAAATCAGATGACAGGGGTGAATCAGAGCGACATCGAGGGGATCAGTCTAGGGTT CGAAGACCAGAAACATTGAGATCCTCTAGTAGAAATGAACATGGCATTAAATCTGATAGT TCAAAAACTGATAAACTAGAACGAAAACACAGGCATGAATCAGGGGACTCAAGGGAAAGA CCATCTTCTGGGGAACAAAAATCAAGACCTGACAGTCCTCGTGTTAAACAAGGAGATTCT AATAAATCAAGATCTGATAAACTTGGTTTTAAATCACCAACTAGTAAAGATGACAAAAGG ACAGAGGGTAACAAGAGTAAAGTAGACACTAATAAAGCACACCCTGACAATAAGGCAGAA TTTCCAAGTTATTTGTTGGGGGGCAGGTCTGGTGCGTTGAAAAATTTTGTCATTCCGAAA ATCAAGAGGGATAAAGATGGCAATGTTACTCAGGAGACAAAGAAAATGGAAATGAAAGGA GAGCCGAAAGACAAAGTAGAAAAAATAGGATTAGTTGAAGATCTAAATAAAGGAGCTAAG CCTGTAGTTGTGCTACAAAAACTGTCTTTGGATGATGTTCAGAAACTTATTAAAGATAGA GAGGACAAATCAAGAAGTTCCCTTAAACCTATCAAGAATAAACCATCAAAGTCAAATAAA GGTAGTATAGATCAATCAGTGTTAAAAGAATTACCCCCTGAACTCCTGGCAGAAATTGAG TCCACCATGCCACTTTGTGAACGTGTGAAAATGAACAAACGCAAGCGTAGCACAGTTAAT GAAAAGCCAAAATATGCTGAAATCAGTTCAGATGAAGATAATGATAGTGATGAAGCTTTT GAATCCTCTAGGAAACGACATAAAAAAGATGATGATAAAGCTTGGGAATATGAAGAGCGT GACAGAAGAAGCTCTGGGGATCATAGGAGAAGTGGCCACTCTCATGAAGGAAGAAGGAGT TCAGGTGGTGGTCGTTATCGAAACCGAAGTCCGTCAGATTCTGACATGGAAGATTATTCT CCTCCTCCCAGCCTTAGTGAGGTTGCTAGGAAAATGAAGAAAAAAGAAAAACAGAAGAAA AGGAAAGCATATGAACCAAAACTAACACCTGAAGAAATGATGGACTCTTCAACTTTTAAG AGATTCACAGCCTCAATAGAGAATATTTTGGATAATTTGGAAGATATGGATTTTACTGCG TTTGGTGATGATGATGAAATTCCTCAGGAACTGCTCTTAGGAAAACATCAGCTTAATGAA CTTGGCAGTGAATCTGCTAAAATAAAAGCAATGGGTATAATGGATAAGCTTTCAACTGAC AAAACTGTGAAAGTCTTAAATATCTTGGAGAAGAATATTCAGGATGGGTCAAAGCTTTCC ACTTTGTTAAATCATAATAACGATACTGAAGAAGAAGAAAGGTTATGGAGAGACCTTATT ATGGAGAGAGTTACAAAATCAGCGGATGCTTGTCTTACAACTATCAACATTATGACATCC CCTAACATGCCAAAAGCTGTGTACATTGAGGATGTAATTGAAAGAGTTATACAGTACACT AAATTTCATTTGCAGAATACACTTTATCCTCAGTATGATCCTGTTTACAGATTAGATCCT CATGGAGGAGGCTTATTAAGTTCAAAAGCAAAACGGGCTAAATGTTCTACCCATAAGCAG AGAGTAATAGTAATGCTTTATAACAAAGTTTGTGACATTGTTAGCAGCTTATCAGAATTG CTAGAGATACAACTTCTTACAGACACAACAATTCTTCAGGTTTCATCTATGGGAATAACA CCATTTTTTGTGGAAAATGTCAGTGAACTACAGTTGTGTGCCATTAAGTTAGTCACTGCA GTATTCTCAAGATATGAAAAACATAGGCAGTTAATTTTGGAAGAAATTTTTACTTCACTT GCAAGATTACCAACCAGCAAGAGGAGTTTAAGGAACTTCAGGTTAAACAGTAGTGATATG GATGGAGAACCTATGTATATTCAGATGGTTACAGCACTGGTTTTACAACTTATTCAGTGT GTGGTACACTTACCATCATCAGAGAAGGACTCTAATGCAGAAGAAGATTCAAATAAAAAA ATTGACCAGGATGTTGTCATTACTAACTCTTATGAAACAGCTATGCGAACAGCCCAAAAC TTCCTCTCCATCTTCCTTAAAAAATGTGGTAGTAAGCAAGGTGAAGAAGATTACAGACCA CTGTTTGAAAATTTTGTTCAAGACCTTCTTTCAACAGTCAATAAGCCTGAATGGCCAGCT GCTGAACTACTCCTTAGTTTGTTAGGGAGACTGTTGGTTCATCAGTTCAGTAACAAGTCA ACAGAGATGGCTTTAAGAGTGGCATCTCTTGATTACCTTGGAACTGTTGCTGCACGGCTA AGAAAAGATGCTGTTACAAGCAAAATGGATCAAGGATCTATAGAACGCATTTTAAAACAG GTTTCAGGAGGGGAAGATGAAATCCAACAATTACAAAAAGCATTGCTTGATTACTTGGAT GAAAACACTGAGACTGATCCTTCACTAGTGTTTTCTCGTAAATTCTATATAGCCCAGTGG TTTCGAGACACAACTCTGGAAACAGAAAAAGCAATGAAATCACAAAAAGATGAAGAATCA TCTGAAGGAACACATCATGCAAAGGAAATTGAGACAACTGGCCAAATTATGCATCGAGCT GAAAACCGAAAAAAGTTTCTTAGAAGCATTATCAAAACCACACCTTCTCAGTTTAGCACA TTAAAGATGAACTCTGATACTGTGGACTATGATGATGCTTGCTTGATTGTTCGATACTTG GCCTCCATGAGGCCGTTTGCCCAGAGCTTTGATATTTATTTGACACAGATCCTACGAGTT CTTGGTGAAAATGCAATTGCTGTTCGAACAAAAGCCATGAAGTGTTTGTCTGAGGTTGTT GCTGTAGACCCCAGTATTCTAGCAAGGCTTGATATGCAACGAGGTGTTCATGGACGATTG ATGGATAATTCGACTAGTGTCCGAGAAGCAGCAGTAGAATTACTAGGTCGATTTGTCCTT TGTCGACCTCAGCTTGCTGAACAGTATTATGATATGCTGATTGAAAGAATATTGGATACT GGTATCAGTGTCAGGAAAAGAGTAATAAAGATTCTCAGAGACATTTGTATTGAACAACCA ACATTTCCAAAAATCACAGAAATGTGTGTAAAAATGATTCGCAGAGTCAATGATGAAGAG GGCATTAAGAAATTAGTAAATGAAACATTCCAGAAACTCTGGTTTACTCCAACTCCACAC AATGACAAAGAAGCAATGACAAGGAAAATTTTAAACATTACCGATGTGGTTGCAGCATGC AGAGATACTGGATATGACTGGTTTGAGCAACTGCTTCAAAACTTGTTGAAGTCCGAAGAG GATTCCTCATATAAACCTGTGAAGAAAGCTTGTACTCAACTTGTTGATAACCTAGTTGAG CACATTCTTAAATATGAGGAATCTCTAGCTGACTCTGACAATAAAGGTGTGAATTCTGGA AGATTGGTAGCTTGCATAACCACTTTGTTCTTATTCAGCAAAATAAGACCCCAGCTCATG GTTAAACATGCAATGACTATGCAACCATACCTTACCACTAAATGTAGTACGCAAAATGAT TTCATGGTTATCTGCAATGTTGCAAAAATCCTAGAGCTAGTTGTACCACTGATGGAGCAT CCAAGTGAAACTTTTCTTGCCACTATTGAGGAAGATCTAATGAAGCTCATCATCAAATAT GGCATGACTGTAGTGCAACATTGTGTGAGCTGTCTTGGAGCTGTTGTAAATAAAGTGACA CAAAATTTTAAATTTGTGTGGGCTTGTTTCAATAGATACTATGGTGCCATTTCAAAATTA AAAAGTCAACACCAAGAGGACCCAAATAACACTTCACTTCTAACAAACAAACCAGCACTT CTTAGATCCCTTTTCACCGTTGGAGCACTATGTCGGCATTTTGATTTTGATCTGGAAGAT TTTAAAGGCAACAGCAAGGTTAACATAAAAGATAAAGTACTTGAACTATTGATGTATTTT ACAAAACACTCAGATGAAGAAGTACAAACAAAAGCTATCATTGGTCTAGGATTTGCCTTT ATTCAGCATCCAAGTCTAATGTTCGAGCAAGAAGTGAAGAATCTATATAATAATATTTTA TCTGATAAGAACTCCTCAGTCAATTTAAAAATACAAGTGTTAAAAAACCTCCAGACCTAC CTACAAGAAGAAGATACACGTATGCAGCAGGCAGATAGAGACTGGAAGAAAGTTGCAAAA CAGGAAGACTTAAAAGAAATGGGTGATGTTTCCTCAGGGATGAGTAGTTCCATCATGCAG CTTTATCTCAAACAGGTGCTTGAGGCATTTTTTCACACCCAGTCAAGTGTACGCCACTTT GCCCTAAATGTCATTGCATTGACTCTAAATCAAGGTCTTATTCATCCAGTTCAGTGTGTG CCATATTTAATTGCTATGGGCACAGACCCAGAACCTGCTATGCGGAACAAGGCTGATCAG CAACTTGTGGAAATAGACAAAAAATATGCTGGATTCATTCATATGAAAGCAGTGGCTGGT ATGAAGATGTCTTACCAGGTACAACAGGCAATCAACACATGCCTAAAAGATCCTGTAAGG GGTTTCAGACAAGACGAGTCCTCTAGCGCTTTGTGTTCACACCTTTACTCCATGATCCGT GGAAACCGCCAACACAGACGAGCCTTTCTTATTTCTTTACTCAACCTCTTTGATGACACA GCAAAAACAGACGTGACTATGCTCTTGTATATAGCAGACAATCTAGCCTGTTTTCCATAC CAGACACAGGAAGAGCCGTTGTTTATAATGCATCATATAGACATTACACTCTCAGTTTCT GGTAGTAACCTACTGCAGTCATTCAAGGAGTCTATGGTAAAGGACAAAAGGAAAGAGAGA AAATCATCACCTAGTAAGGAAAATGAGTCAAGCGACAGTGAAGAAGAAGTTTCCAGGCCT CGGAAGTCACGGAAACGTGTAGATTCAGATTCAGATTCAGATTCAGAAGACGATATAAAT TCAGTGATGAAATGTTTGCCAGAAAATTCAGCTCCTTTAATCGAATTTGCAAATGTGTCC CAGGGTATTTTATTACTTCTCATGTTAAAACAACATTTGAAGAATCTTTGTGGATTTTCT GATAGTAAAATTCAGAAGTACTCTCCATCTGAATCTGCAAAAGTATATGATAAAGCGATA AACCGAAAAACAGGAGTTCATTTTCATCCAAAACAAACACTGGACTTCCTGCGGAGTGAC ATGGCTAATTCCAAAATCACAGAAGAGGTGAAAAGGAGTATAGTAAAACAGTATCTAGAT TTCAAACTTCTCATGGAACATCTGGACCCTGATGAAGAAGAAGAAGAAGGGGAGGTTTCA GCTAGCACAAATGCTCGGAACAAAGCAATTACCTCACTGCTTGGAGGAGGCAGCCCTAAA AATAATACAGCAGCAGAGACAGAAGATGATGAAAGTGATGGGGAGGATAGAGGAGGAGGC ACTTCAGGGTCATTGAGAAGGTCAAAACGAAATTCAGACTCTACGGAGTTGGCAGCACAG ATGAATGAAAGTGTTGACGTCATGGATGTCATCGCTATTTGCTGTCCAAAGTACAAAGAT CGACCACAAATTGCAAGAGTAGTGCAGAAAACCAGCAGTGGCTTCAGTGTTCAGTGGATG GCAGGCTCCTACAGTGGCTCCTGGACTGAGGCTAAGCGCCGTGATGGCCGCAAACTGGTG CCTTGGGTAGACACTATTAAAGAGTCAGACATTATTTACAAAAAAATTGCTCTAACGAGT GCTAATAAGCTGACTAATAAAGTTGTTCAGACTTTACGATCCCTGTATGCCGCCAAGGAT GGGACTTCCAGCTAA |
| Restriction Sites | Please inquire |
| ACCN | NM_133433 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_133433.2, NP_597677.2 |
| RefSeq Size | 9717 bp |
| RefSeq ORF | 8415 bp |
| Locus ID | 25836 |
| UniProt ID | Q6KC79 |
| Gene Summary | This gene encodes the homolog of the Drosophila melanogaster Nipped-B gene product and fungal Scc2-type sister chromatid cohesion proteins. The Drosophila protein facilitates enhancer-promoter communication of remote enhancers and plays a role in developmental regulation. It is also homologous to a family of chromosomal adherins with broad roles in sister chromatid cohesion, chromosome condensation, and DNA repair. The human protein has a bipartite nuclear targeting sequence and a putative HEAT repeat. Condensins, cohesins and other complexes with chromosome-related functions also contain HEAT repeats. Mutations in this gene result in Cornelia de Lange syndrome, a disorder characterized by dysmorphic facial features, growth delay, limb reduction defects, and cognitive disability. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (A) encodes the longer isoform (A). |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211489 | NIPBL (Myc-DDK-tagged)-Human Nipped-B homolog (Drosophila) (NIPBL), transcript variant A |
CNY 27,256.00 |
|
| RC211489L1 | Lenti ORF clone of Human Nipped-B homolog (Drosophila) (NIPBL), transcript variant A, Myc-DDK-tagged |
CNY 20,890.00 |
|
| RG211489 | NIPBL (tGFP-tagged) - Human Nipped-B homolog (Drosophila) (NIPBL), transcript variant A |
CNY 28,856.00 |
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