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Myoferlin (MYOF) (NM_133337) Human Untagged Clone
CAT＃: SC309095
MYOF (untagged)-Human myoferlin (MYOF), transcript variant 2
CNY 39,430.00
货期*
12周
规格
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | FER1L3; HAE7 |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_133337, the custom clone sequence may differ by one or more nucleotides
ATGCTGCGAGTGATTGTGGAATCTGCCAGCAATATCCCTAAAACGAAATTTGGCAAGCCG GATCCTATTGTTTCTGTCATTTTTAAGGATGAGAAAAAGAAAACAAAGAAAGTTGATAAT GAATTGAACCCTGTCTGGAATGAGATTTTGGAGTTTGACTTGAGGGGTATACCACTGGAC TTTTCATCTTCCCTTGGGATTATTGTGAAAGATTTTGAGACAATTGGACAAAATAAATTA ATTGGCACGGCGACTGTAGCCCTGAAGGACCTGACTGGTGACCAGAGCAGATCCCTGCCG TACAAGCTGATCTCCCTGCTAAATGAAAAAGGGCAAGATACTGGGGCCACCATTGACTTG GTGATCGGCTATGATCCGCCTTCTGCTCCACATCCAAATGACCTGAGCGGGCCCAGCGTG CCAGGCATGGGAGGAGATGGGGAAGAAGATGAAGGTGATGAAGACAGGTTGGACAATGCA GTCAGGGGCCCTGGGCCCAAGGGGCCAGTTGGGACGGTGTCGGAAGCTCAGCTTGCTCGG AGGCTCACCAAAGTAAAGAACAGCCGGCGGATGCTGTCAAATAAGCCACAGGACTTCCAG ATCCGCGTCCGAGTGATTGAGGGCCGACAGTTAAGTGGTAACAACATAAGGCCTGTGGTC AAAGTTCACGTCTGTGGCCAGACACACCGAACAAGAATCAAGAGAGGAAACAACCCTTTT TTTGATGAGTTGTTTTTCTACAATGTCAACATGACCCCTTCTGAATTGATGGATGAGATC ATCAGCATCCGGGTTTATAATTCTCACTCTCTGCGGGCAGATTGTCTGATGGGGGAATTT AAGATTGATGTTGGATTTGTTTATGATGAACCTGGCCATGCTGTCATGAGAAAGTGGCTT CTTCTCAATGACCCGGAAGATACCAGTTCAGGTTCTAAAGGTTATATGAAAGTCAGCATG TTTGTCCTGGGAACCGGAGATGAGCCTCCTCCTGAGAGACGAGATCGTGATAATGACAGT GATGATGTGGAGAGTAATTTGTTACTCCCTGCTGGCATTGCCCTCCGGTGGGTGACCTTC TTGCTGAAAATCTACCGAGCTGAGGACATCCCCCAGATGGATGATGCCTTCTCACAGACA GTAAAGGAAATATTTGGAGGCAATGCAGATAAGAAAAATCTCGTGGATCCTTTTGTAGAA GTTTCCTTTGCTGGAAAAAAGGTTTGTACAAACATAATTGAGAAAAATGCAAACCCAGAG TGGAATCAGGTCGTCAATCTTCAGATCAAGTTTCCTTCAGTGTGTGAAAAAATAAAACTA ACAATATATGACTGGGACCGTCTTACTAAAAATGATGTAGTTGGAACAACATATCTACAC CTCTCTAAAATTGCTGCCTCTGGTGGGGAAGTGGAAGTAAACACAGGAGAAACAGAGGTA GGCTTTGTTCCAACGTTTGGACCTTGTTACCTGAATCTTTATGGAAGCCCCAGAGAGTAC ACGGGATTCCCAGACCCCTATGATGAGCTGAATACTGGAAAGGGGGAAGGAGTTGCCTAC AGAGGCAGGATCTTGGTTGAATTAGCCACTTTTCTTGAGAAGACACCACCAGATAAAAAG CTTGAGCCCATTTCAAATGATGACCTGCTGGTTGTTGAGAAATACCAGCGAAGGCGGAAG TACAGCCTGTCTGCCGTGTTTCATTCAGCCACCATGTTGCAAGATGTTGGTGAGGCCATT CAGTTTGAAGTCAGCATTGGGAACTATGGCAACAAGTTTGACACCACCTGTAAGCCTTTG GCATCAACAACTCAGTACAGCCGTGCTGTATTTGATGGCAACTACTATTATTACTTGCCT TGGGCCCACACCAAGCCAGTTGTTACCCTGACTTCATACTGGGAGGATATTAGTCATCGC CTGGATGCGGTGAACACTCTCCTAGCTATGGCAGAACGGCTGCAAACAAATATAGAAGCT CTAAAATCAGGGATACAAGGTAAAATTCCTGCAAACCAGCTGGCTGAATTGTGGCTGAAG CTGATAGATGAAGTTATAGAAGACACGAGATACACGTTGCCTCTCACAGAAGGAAAAGCC AACGTCACAGTTCTCGATACTCAGATCCGAAAGCTGCGGTCCAGGTCTCTCTCCCAAATA CATGAGGCGGCTGTGAGGATGAGGTCGGAAGCCACAGATGTGAAGTCCACACTGGCAGAA ATTGAGGACTGGCTTGATAAATTAATGCAGCTGACTGAAGAGCCACAGAACAGCATGCCT GACATCATCATCTGGATGATCCGGGGAGAGAAGAGACTGGCCTATGCACGAATTCCCGCA CATCAGGTCTTGTACTCCACCAGTGGTGAGAATGCATCTGGAAAATACTGTGGGAAAACC CAAACCATCTTTCTGAAGTATCCACAGGAGAAAAACAACGGGCCAAAGGTGCCTGTGGAG TTGCGAGTGAACATCTGGCTAGGCTTAAGTGCTGTGGAGAAGAAGTTTAACAGCTTCGCA GAAGGAACTTTCACCGTCTTTGCTGAAATGTATGAAAATCAAGCTCTCATGTTTGGAAAA TGGGGTACTTCTGGATTAGTAGGACGTCATAAGTTTTCTGATGTCACAGGAAAAATAAAA CTCAAGAGGGAATTTTTTCTGCCTCCAAAAGGCTGGGAATGGGAAGGAGAGTGGATAGTT GATCCTGAAAGAAGCTTGCTGACTGAGGCAGATGCAGGTCACACGGAGTTCACTGATGAA GTCTATCAGAACGAGAGCCGCTACCCCGGGGGCGACTGGAAGCCGGCCGAGGACACCTAC ACGGATGCGAACGGCGATAAAGCAGCATCACCCAGCGAGTTGACTTGTCCTCCAGGTTGG GAATGGGAAGATGATGCATGGTCTTATGACATAAATCGAGCGGTGGATGAGAAAGGCTGG GAATATGGAATCACCATTCCTCCTGATCATAAGCCCAAATCCTGGGTTGCAGCAGAGAAA ATGTACCACACTCATAGACGGCGAAGGCTGGTCCGAAAACGCAAGAAAGATTTAACACAG ACTGCTTCAAGCACCGCAAGGGCCATGGAGGAATTGCAAGACCAAGAGGGCTGGGAATAT GCTTCTCTAATTGGCTGGAAATTTCACTGGAAACAACGTAGTTCAGATACCTTCCGCCGC AGACGCTGGAGGAGAAAAATGGCTCCTTCAGAAACACATGGTGCAGCTGCCATCTTTAAA CTTGAAGGTGCCCTTGGGGCAGACACTACCGAAGATGGGGATGAGAAGAGCCTGGAGAAA CAGAAGCACAGTGCCACCACTGTGTTCGGAGCAAACACCCCCATTGTTTCCTGCAATTTT GACAGAGTCTACATCTACCATCTGCGCTGCTATGTCTATCAAGCCAGAAACCTCTTGGCT TTAGATAAGGATAGCTTTTCAGATCCATATGCTCATATCTGTTTCCTCCATCGGAGCAAA ACCACTGAGATCATCCATTCAACCCTGAATCCCACGTGGGACCAAACAATTATATTCGAT GAAGTTGAAATCTATGGGGAACCCCAAACAGTTCTACAGAATCCACCCAAAGTTATCATG GAACTTTTTGACAATGACCAAGTGGGCAAAGATGAATTTTTAGGACGAAGCATTTTCTCT CCTGTGGTGAAACTGAACTCAGAAATGGACATCACACCCAAACTTCTCTGGCACCCAGTA ATGAATGGAGACAAAGCCTGCGGGGATGTTCTTGTAACTGCAGAGCTGATTCTGAGGGGC AAGGATGGCTCCAACCTTCCCATTCTTCCCCCTCAAAGGGCGCCAAATCTATACATGGTC CCCCAGGGGATCAGGCCTGTGGTCCAGCTCACTGCCATTGAGATTCTAGCTTGGGGCTTA AGAAATATGAAAAACTTCCAGATGGCTTCTATCACATCCCCCAGTCTTGTTGTGGAGTGT GGAGGAGAAAGGGTGGAATCGGTGGTGATCAAAAACCTTAAGAAGACACCCAACTTTCCA AGTTCTGTTCTCTTCATGAAAGTGTTCTTGCCCAAGGAGGAATTGTACATGCCCCCACTG GTGATCAAGGTCATCGACCACAGGCAGTTTGGGCGGAAGCCTGTCGTCGGCCAGTGCACC ATCGAGCGCCTGGACCGCTTTCGCTGTGACCCTTATGCAGGGAAAGAGGACATCGTCCCA CAGCTCAAAGCCTCCCTTCTGTCTGCCCCACCATGCCGGGACATCGTTATCGAAATGGAA GACACCAAACCATTACTGGCTTCTAAGCTGACAGAAAAGGAGGAAGAAATCGTGGACTGG TGGAGTAAATTTTATGCTTCCTCAGGGGAACATGAAAAATGCGGACAGTATATTCAGAAA GGCTATTCCAAGCTCAAGATATATAATTGTGAACTAGAAAATGTAGCAGAATTTGAGGGC CTGACAGACTTCTCAGATACGTTCAAGTTGTACCGAGGCAAGTCGGATGAAAATGAAGAT CCTTCTGTGGTTGGAGAGTTTAAGGGCTCCTTTCGGATCTACCCTCTGCCGGATGACCCC AGCGTGCCAGCCCCTCCCAGACAGTTTCGGGAATTACCTGACAGCGTCCCACAGGAATGC ACGGTTAGGATTTACATTGTTCGAGGCTTAGAGCTCCAGCCCCAGGACAACAATGGCCTG TGTGACCCTTACATAAAAATAACACTGGGCAAAAAAGTCATTGAAGACCGAGATCACTAC ATTCCCAACACTCTCAACCCAGTCTTTGGCAGGATGTACGAACTGAGCTGCTACTTACCT CAAGAAAAAGACCTGAAAATTTCTGTCTATGATTATGACACCTTTACCCGGGATGAAAAA GTAGGAGAAACAATTATTGATCTGGAAAACCGATTCCTTTCCCGCTTTGGGTCCCACTGC GGCATACCAGAGGAGTACTGTGTTTCTGGAGTCAATACCTGGCGAGATCAACTGAGACCA ACACAGCTGCTTCAAAATGTCGCCAGATTCAAAGGCTTCCCACAACCCATCCTTTCCGAA GATGGGAGTAGAATCAGATATGGAGGACGAGACTACAGCTTGGATGAATTTGAAGCCAAC AAAATCCTGCACCAGCACCTCGGGGCCCCTGAAGAGCGGCTTGCTCTTCACATCCTCAGG ACTCAGGGGCTGGTCCCTGAGCACGTGGAAACAAGGACTTTGCACAGCACCTTCCAGCCC AACATTTCCCAGGGAAAACTTCAGATGTGGGTGGATGTTTTCCCCAAGAGTTTGGGGCCA CCAGGCCCTCCTTTCAACATCACACCCCGGAAAGCCAAGAAATACTACCTGCGTGTGATC ATCTGGAACACCAAGGACGTTATCTTGGACGAGAAAAGCATCACAGGAGAGGAAATGAGT GACATCTACGTCAAAGGCTGGATTCCTGGCAATGAAGAAAACAAACAGAAAACAGATGTC CATTACAGATCTTTGGATGGTGAAGGGAATTTTAACTGGCGATTTGTTTTCCCGTTTGAC TACCTTCCAGCCGAACAACTCTGTATCGTTGCGAAAAAAGAGCATTTCTGGAGTATTGAC CAAACGGAATTTCGAATCCCACCCAGGCTGATCATTCAGATATGGGACAATGACAAGTTT TCTCTGGATGACTACTTGGGTTTCCTAGAACTTGACTTGCGTCACACGATCATTCCTGCA AAATCACCAGAGAAATGCAGATTGGACATGATTCCGGACCTCAAAGCCATGAACCCCCTT AAAGCCAAGACAGCCTCCCTCTTTGAGCAGAAGTCCATGAAAGGATGGTGGCCATGCTAC GCAGAGAAAGATGGCGCCCGCGTAATGGCTGGGAAAGTGGAGATGACATTGGAAATCCTC AACGAGAAGGAGGCCGACGAGAGGCCAGCCGGGAAGGGGCGGGACGAACCCAACATGAAC CCCAAGCTGGACTTACCAAATCGACCAGAAACCTCCTTCCTCTGGTTCACCAACCCATGC AAGACCATGAAGTTCATCGTGTGGCGCCGCTTTAAGTGGGTCATCATCGGCTTGCTGTTC CTGCTTATCCTGCTGCTCTTCGTGGCCGTGCTCCTCTACTCTTTGCCGAACTATTTGTCA ATGAAGATTGTAAAGCCAAATGTGTAA |
| Restriction Sites | Please inquire |
| ACCN | NM_133337 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_133337.1, NP_579899.1 |
| RefSeq Size | 6790 bp |
| RefSeq ORF | 6147 bp |
| Locus ID | 26509 |
| UniProt ID | Q9NZM1 |
| Domains | C2, DysFN, DysFC |
| Protein Families | Transmembrane |
| Gene Summary | Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined. [provided by RefSeq, Dec 2008] Transcript Variant: This variant (2) lacks a 39 nt coding region as compared to transcript variant 1. As a result, variant 2 encodes an isoform (b) that lacks an internal 13 aa segment as compared to isoform a, which is encoded by variant 1. |
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