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NAIP (NM_022892) Human Untagged Clone
CAT＃: SC315876
NAIP (untagged)-Human NLR family, apoptosis inhibitory protein (NAIP), transcript variant 2
CNY 23,940.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BIRC1; NLRB1; psiNAIP |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC315876 representing NM_022892.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGCCACTTCATATTGGGGACTTCGTCTGGGATTCCAAGGTGCATTCATTGCAAAGTTCCTTAAATATT TTCTCACTGCTTCCTACTAAAGGACGGACAGAGCATTTGTTCTTCAGCCACATACTTTCCTTCCACTGG CCAGCATTCTCCTCTATTAGACTAGAACTGTGGATAAACCTCAGATGTGAATTTCTTCGGAGTAAGAAA TCCTCAGAGGAAATTACCCAGTATATTCAAAGCTACAAGGGATTTGTTGACATAACGGGAGAACATTTT GTGAATTCCTGGGTCCAGAGAGAATTACCTATGGCATCAGCTTATTGCAATGACAGCATCTTTGCTTAC GAAGAACTACGGCTGGACTCTTTTAAGGACTGGCCCCGGGAATCAGCTGTGGGAGTTGCAGCACTGGCC AAAGCAGGTCTTTTCTACACAGGTATAAAGGACATCGTCCAGTGCTTTTCCTGTGGAGGGTGTTTAGAG AAATGGCAGGAAGGTGATGACCCATTAGACGATCACACCAGATGTTTTCCCAATTGTCCATTTCTCCAA AATATGAAGTCCTCTGCGGAAGTGACTCCAGACCTTCAGAGCCGTGGTGAACTTTGTGAATTACTGGAA ACCACAAGTGAAAGCAATCTTGAAGATTCAATAGCAGTTGGTCCTATAGTGCCAGAAATGGCACAGGGT GAAGCCCAGTGGTTTCAAGAGGCAAAGAATCTGAATGAGCAGCTGAGAGCAGCTTATACCAGCGCCAGT TTCCGCCACATGTCTTTGCTTGATATCTCTTCCGATCTGGCCACGGACCACTTGCTGGGCTGTGATCTG TCTATTGCTTCAAAACACATCAGCAAACCTGTGCAAGAACCTCTGGTGCTGCCTGAGGTCTTTGGCAAC TTGAACTCTGTCATGTGTGTGGAGGGTGAAGCTGGAAGTGGAAAGACGGTCCTCCTGAAGAAAATAGCT TTTCTGTGGGCATCTGGATGCTGTCCCCTGTTAAACAGGTTCCAGCTGGTTTTCTACCTCTCCCTTAGT TCCACCAGACCAGACGAGGGGCTGGCCAGTATCATCTGTGACCAGCTCCTAGAGAAAGAAGGATCTGTT ACTGAAATGTGCGTGAGGAACATTATCCAGCAGTTAAAGAATCAGGTCTTATTCCTTTTAGATGACTAC AAAGAAATATGTTCAATCCCTCAAGTCATAGGAAAACTGATTCAAAAAAACCACTTATCCCGGACCTGC CTATTGATTGCTGTCCGTACAAACAGGGCCAGGGACATCCGCCGATACCTAGAGACCATTCTAGAGATC AAAGCATTTCCCTTTTATAATACTGTCTGTATATTACGGAAGCTCTTTTCACATAATATGACTCGTCTG CGAAAGTTTATGGTTTACTTTGGAAAGAACCAAAGTTTGCAGAAGATACAGAAAACTCCTCTCTTTGTG GCGGCGATCTGTGCTCATTGGTTTCAGTATCCTTTTGACCCATCCTTTGATGATGTGGCTGTTTTCAAG TCCTATATGGAACGCCTTTCCTTAAGGAACAAAGCGACAGCTGAAATTCTCAAAGCAACTGTGTCCTCC TGTGGTGAGCTGGCCTTGAAAGGGTTTTTTTCATGTTGCTTTGAGTTTAATGATGATGATCTCGCAGAA GCAGGGGTTGATGAAGATGAAGATCTAACCATGTGCTTGATGAGCAAATTTACAGCCCAGAGACTAAGA CCATTCTACCGGTTTTTAAGTCCTGCCTTCCAAGAATTTCTTGCGGGGATGAGGCTGATTGAACTCCTG GATTCAGATAGGCAGGAACATCAAGATTTGGGACTGTATCATTTGAAACAAATCAACTCACCCATGATG ACTGTAAGCGCCTACAACAATTTTTTGAACTATGTCTCCAGCCTCCCTTCAACAAAAGCAGGGCCCAAA ATTGTGTCTCATTTGCTCCATTTAGTGGATAACAAAGAGTCATTGGAGAATATATCTGAAAATGATGAC TACTTAAAGCACCAGCCAGAAATTTCACTGCAGATGCAGTTACTTAGGGGATTGTGGCAAATTTGTCCA CAAGCTTACTTTTCAATGGTTTCAGAACATTTACTGGTTCTTGCCCTGAAAACTGCTTATCAAAGCAAC ACTGTTGCTGCGTGTTCTCCATTTGTTTTGCAATTCCTTCAAGGGAGAACACTGACTTTGGGTGCGCTT AACTTACAGTACTTTTTCGACCACCCAGAAAGCTTGTCATTGTTGAGGAGCATCCACTTCCCAATACGA GGAAATAAGACATCACCCAGAGCACATTTTTCAGTTCTGGAAACATGTTTTGACAAATCACAGGTGCCA ACTATAGATCAGGACTATGCTTCTGCCTTTGAACCTATGAATGAATGGGAGCGAAATTTAGCTGAAAAA GAGGATAATGTAAAGAGCTATATGGATATGCAGCGCAGGGCATCACCAGACCTTAGTACTGGCTATTGG AAACTTTCTCCAAAGCAGTACAAGATTCCCTGTCTAGAAGTCGATGTGAATGATATTGATGTTGTAGGC CAGGATATGCTTGAGATTCTAATGACAGTTTTCTCAGCTTCACAGCGCATCGAACTCCATTTAAACCAC AGCAGAGGCTTTATAGAAAGCATCCGCCCAGCTCTTGAGCTGTCTAAGGCCTCTGTCACCAAGTGCTCC ATAAGCAAGTTGGAACTCAGCGCAGCCGAACAGGAACTGCTTCTCACCCTGCCTTCCCTGGAATCTCTT GAAGTCTCAGGGACAATCCAGTCACAAGACCAAATCTTTCCTAATCTGGATAAGTTCCTGTGCCTGAAA GAACTGTCTGTGGATCTGGAGGGCAATATAAATGTTTTTTCAGTCATTCCTGAAGAATTTCCAAACTTC CACCATATGGAGAAATTATTGATCCAAATTTCAGCTGAGTATGATCCTTCCAAACTAGTAAAATTAATT CAAAATTCTCCAAACCTTCATGTTTTCCATCTGAAGTGTAACTTCTTTTCGGATTTTGGGTCTCTCATG ACTATGCTTGTTTCCTGTAAGAAACTCACAGAAATTAAGTTTTCGGATTCATTTTTTCAAGCCGTCCCA TTTGTTGCCAGTTTGCCAAATTTTATTTCTCTGAAGATATTAAATCTTGAAGGCCAGCAATTTCCTGAT GAGGAAACATCAGAAAAATTTGCCTACATTTTAGGTTCTCTTAGTAACCTGGAAGAATTGATCCTTCCT ACTGGGGATGGAATTTATCGAGTGGCCAAACTGATCATCCAGCAGTGTCAGCAGCTTCATTGTCTCCGA GTCCTCTCATTTTTCAAGACTTTGAATGATGACAGCGTGGTGGAAATTGCCAAAGTAGCAATCAGTGGA GGTTTCCAGAAACTTGAGAACCTAAAGCTTTCAATCAATCACAAGATTACAGAGGAAGGATACAGAAAT TTCTTTCAAGCACTGGACAACATGCCAAACTTGCAGGAGTTGGACATCTCCAGGCATTTCACAGAGTGT ATCAAAGCTCAGGCCACAACAGTCAAGTCTTTGAGTCAATGTGTGTTACGACTACCAAGGCTCATTAGA CTGAACATGTTAAGTTGGCTCTTGGATGCAGATGATATTGCATTGCTTAATGTCATGAAAGAAAGACAT CCTCAATCTAAGTACTTAACTATTCTCCAGAAATGGATACTGCCGTTCTCTCCAATCATTCAGAAATAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_022892 |
| Insert Size | 3726 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_022892.1 |
| RefSeq Size | 5880 bp |
| RefSeq ORF | 3726 bp |
| Locus ID | 4671 |
| UniProt ID | Q13075 |
| Protein Families | Druggable Genome |
| Protein Pathways | NOD-like receptor signaling pathway |
| MW | 141.3 kDa |
| Gene Summary | This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. This copy of the gene is full length; additional copies with truncations and internal deletions are also present in this region of chromosome 5q13. It is thought that this gene is a modifier of spinal muscular atrophy caused by mutations in a neighboring gene, SMN1. The protein encoded by this gene contains regions of homology to two baculovirus inhibitor of apoptosis proteins, and it is able to suppress apoptosis induced by various signals. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Nov 2016] Transcript Variant: This variant (2), also known as psiNAIP, lacks two internal exons in the 5' coding region, as compared to variant 1. The resulting isoform (2) has an alternate and shorter N-terminus, as compared to isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC216819 | NAIP (Myc-DDK-tagged)-Human NLR family, apoptosis inhibitory protein (NAIP), transcript variant 2 |
CNY 8,640.00 |
|
| RC216819L3 | Lenti-ORF clone of NAIP (Myc-DDK-tagged)-Human NLR family, apoptosis inhibitory protein (NAIP), transcript variant 2 |
CNY 14,250.00 |
|
| RC216819L4 | Lenti-ORF clone of NAIP (mGFP-tagged)-Human NLR family, apoptosis inhibitory protein (NAIP), transcript variant 2 |
CNY 14,250.00 |
|
| RG216819 | NAIP (tGFP-tagged) - Human NLR family, apoptosis inhibitory protein (NAIP), transcript variant 2 |
CNY 13,590.00 |
