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SENP6 (NM_001100409) Human Untagged Clone
CAT＃: SC316860
SENP6 (untagged)-Human SUMO1/sentrin specific peptidase 6 (SENP6), transcript variant 2
CNY 10,450.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | SSP1; SUSP1 |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_001100409, the custom clone sequence may differ by one or more nucleotides
ATGGCGGCCGGCAAGAGCGGCGGTAGCGCAGGGGAGATTACTTTTCTGGAAGCTTTGGCT AGATCAGAGTCTAAGAGAGATGGAGGTTTTAAAAATAATTGGAGCTTTGATCATGAAGAA GAAAGTGAAGGAGATACAGATAAAGATGGGACAAATCTGCTCAGTGTGGATGAAGATGAG GATTCTGAAACCTCAAAAGGAAAAAAGTTAAATCGTCGATCTGAAATTGTTGCTAATAGC TCTGGTGAATTCATCTTGAAGACATATGTAAGACGAAACAAGTCTGAAAGTTTTAAAACT TTGAAAGGCAACCCAATTGGACTTAACATGTTGAGCAACAATAAGAAATTGAGTGAAAAT ACGCAAAATACGTCATTATGTTCTGGAACTGTAGTTCATGGTAGACGTTTTCATCATGCT CATGCACAGATACCAGTAGTAAAAACAGCAGCCCAAAGGAAAGAATACCCACCTCATGTC CAAAAAGTTGAAATTAATCCTGTAAGGTTAAGTCGGCTCCAAGGTGTTGAACGTATAATG AAGAAAACAGAAGAGTCCGAATCACAAGTGGAGCCTGAAATTAAGAGGAAAGTACAACAG AAACGACACTGTAGTACCTATCAGCCTACTCCTCCTCTATCTCCTGCTTCAAAAAAATGT TTAACCCATTTAGAGGATTTGCAAAGAAATTGCAGACAAGCTATTACTTTGAATGAGTCT ACTGGACCATTATTAAGAACGTCAATTCATCAGAATTCTGGAGGACAGAAGTCACAAAAC ACAGGATTAACAACCAAGAAGTTTTATGGCAACAATGTGGAAAAGGTTCCAATTGATATT ATTGTGAATTGTGATGACAGTAAACACACTTATTTACAGACTAATGGAAAAGTCATTTTA CCTGGGGCAAAAATACCCAAAATCACAAACTTGAAAGAAAGGAAAACAAGTTTGTCAGAC CTAAATGATCCAATCATTTTGTCCAGTGATGATGATGATGACAACGACAGAACTAACAGA AGAGAAAGCATATCTCCTCAGCCTGCTGATTCAGCATGTTCTTCCCCTGCACCATCCACT GGAAAAGTAGAAGCAGCGCTAAATGAAAATACTTGCAGAGCAGAGCGTGAACTACGAAGC ATTCCAGAAGACTCAGAGTTAAATACAGTTACATTGCCAAGAAAAGCAAGAATGAAAGAC CAGTTTGGCAATTCTATTATCAACACACCTCTGAAACGTCGTAAAGTGTTTTCTCAAGAA CCTCCAGATGCTTTAGCTTTAAGCTGCCAAAGTTCCTTTGACAGTGTCATTTTAAACTGT CGAAGTATACGAGTAGGAACACTCTTCCGGCTGTTAATAGAGCCTGTAATTTTTTGTTTA GATTTTATCAAGATACAGCTAGACGAACCAGACCATGATCCTGTAGAGATTATATTAAAT ACCTCTGATCTAACTAAATGTGAATGGTGTAATGTCCGAAAATTACCTGTAGTGTTTCTT CAAGCAATTCCAGCAGTTTATCAAAAGCTGAGCATCCAACTGCAAATGAATAAGGAGGAT AAAGTTTGGAATGATTGTAAAGGAGTAAATAAATTAACAAATTTAGAAGAACAATATATA ATTTTAATTTTTCAAAATGGCCTTGATCCTCCGGCAAATATGGTATTTGAAAGTATCATT AATGAAATTGGTATAAAGAATAACATCTCCAATTTTTTTGCGAAAATTCCCTTTGAAGAA GCTAATGGCAGACTTGTTGCCTGTACAAGAACCTATGAAGAGAGCATCAAAGGAAGTTGT GGGCAAAAGGAAAACAAAATTAAAACTGTATCATTTGAATCTAAAATACAACTTAGAAGC AAACAAGAATTTCAGTTTTTTGATGAAGAAGAAGAAACTGGAGAAAACCACACCATCTTC ATTGGCCCAGTAGAAAAGTTGATAGTATATCCACCACCTCCAGCTAAGGGAGGCATCTCT GTTACCAATGAGGACCTGCACTGTCTAAATGAAGGAGAATTTTTAAATGATGTTATTATA GACTTTTATTTGAAATACTTGGTGCTTGAAAAACTGAAGAAGGAAGACGCTGACCGAATT CATATATTCAGTTCTTTTTTCTATAAACGCCTTAATCAGAGAGAGAGGAGAAATCATGAA ACAACTAATCTGTCAATACAGCAAAAACGGCATGGGAGAGTAAAAACATGGACCCGGCAC GTAGATATTTTTGAGAAGGATTTTATTTTTGTACCCCTTAATGAAGCTGCACACTGGTTT TTGGCTGTTGTTTGTTTCCCCGGTTTGGAAAAACCAAAGTATGAACCTAATCCTCATTAC CATGAAAATGCTGTCATACAGAAATGTTCAACTGTAGAGGACAGTTGTATTTCTTCTTCA GCCAGTGAAATGGAGAGTTGTTCACAAAACTCTTCTGCCAAGCCTGTAATTAAGAAGATG CTAAACAAAAAACATTGCATAGCTGTAATTGATTCCAATCCTGGGCAGGAAGAAAGTGAC CCTCGTTATAAGAGAAACATATGCAGTGTAAAATACAGTGTGAAAAAAATAAATCATACT GCGAGTGAAAATGAAGAATTCAATAAAGGAGAATCTACATCCCAGAAAGTTGCTGATAGG ACTAAAAGTGAGAATGGCCTACAGAATGAAAGTTTAAGTTCCACACATCATACAGATGGC TTAAGCAAAATCAGACTAAACTATAGCGATGAATCACCTGAAGCTGGTAAAATGCTTGAA GATGAACTCGTCGACTTCTCAGAAGATCAGGATAACCAGGATGATAGCAGTGACGATGGA TTCCTCGCTGATGACAACTGCAGTTCAGAAATAGGACAGTGGCATTTAAAGCCTACTATC TGTAAACAACCTTGTATCCTACTTATGGACTCACTCCGAGGCCCTTCTCGGTCAAATGTT GTCAAAATTTTAAGAGAGTATTTAGAAGTGGAATGGGAAGTTAAAAAAGGAAGCAAAAGA AGTTTTTCCAAAGATGTTATGAAGGGCTCTAATCCAAAAGTACCACAGCAAAACAACTTC AGTGACTGTGGTGTATATGTATTGCAGTATGTAGAGAGCTTTTTTGAGAATCCAATTCTC AGTTTTGAACTACCTATGAATTTGGCAAACTGGTTTCCTCCACCAAGAATGAGAACAAAA AGAGAAGAAATCCGAAACATAATTCTGAAGCTACAGGAAGATCAGAGCAAAGAGAAAAGA AAGCATAAGGACACTTACTCAACAGAAGCACCTTTAGGCGAAGGAACAGAACAATATGTC AATAGTATCTCAGAT |
| Restriction Sites | Please inquire |
| ACCN | NM_001100409 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001100409.1, NP_001093879.1 |
| RefSeq Size | 6624 bp |
| RefSeq ORF | 3318 bp |
| Locus ID | 26054 |
| UniProt ID | Q9GZR1 |
| Protein Families | Druggable Genome, Protease |
| Gene Summary | Ubiquitin-like molecules (UBLs), such as SUMO1 (UBL1; MIM 601912), are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1 (MIM 602362) to the nuclear pore complex, as well as in stabilization of I-kappa-B-alpha (NFKBIA; MIM 164008) from degradation by the 26S proteasome. Like ubiquitin, UBLs are synthesized as precursor proteins, with 1 or more amino acids following the C-terminal glycine-glycine residues of the mature UBL protein. Thus, the tail sequences of the UBL precursors need to be removed by UBL-specific proteases, such as SENP6, prior to their conjugation to target proteins (Kim et al., 2000 [PubMed 10799485]). SENPs also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009] Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1, resulting in a shorter protein (isoform 2), compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC217424 | SENP6 (Myc-DDK-tagged)-Human SUMO1/sentrin specific peptidase 6 (SENP6), transcript variant 2 |
CNY 11,020.00 |
|
| RC217424L3 | Lenti-ORF clone of SENP6 (Myc-DDK-tagged)-Human SUMO1/sentrin specific peptidase 6 (SENP6), transcript variant 2 |
CNY 12,920.00 |
|
| RC217424L4 | Lenti-ORF clone of SENP6 (mGFP-tagged)-Human SUMO1/sentrin specific peptidase 6 (SENP6), transcript variant 2 |
CNY 12,920.00 |
|
| RG217424 | SENP6 (tGFP-tagged) - Human SUMO1/sentrin specific peptidase 6 (SENP6), transcript variant 2 |
CNY 10,064.00 |
