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MIA3 (NM_198551) Human Untagged Clone
CAT＃: SC318691
MIA3 (untagged)-Human melanoma inhibitory activity family, member 3 (MIA3)
CNY 36,670.00
货期*
9周
规格
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ARNT; D320; TANGO; TANGO1; UNQ6077 |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_198551, the custom clone sequence may differ by one or more nucleotides
ATGGCTGCGGCGCCTGGGCTGCTCGTCTGGCTGCTCGTGCTCCGGCTGCCCTGGCGGGTG CCGGGCCAGCTGGACCCCAGCACTGGCCGGCGGTTCTCGGAGCACAAACTCTGCGCGGAC GACGAATGCAGCATGTTAATGTACCGCGGTGAGGCTCTTGAAGATTTCACAGGCCCGGAT TGTCGTTTTGTGAATTTTAAAAAAGGTGATCCTGTATATGTTTACTATAAACTGGCAAGA GGATGGCCTGAAGTTTGGGCTGGAAGTGTTGGACGCACTTTTGGATATTTTCCAAAAGAT TTAATCCAGGTAGTTCATGAATATACCAAAGAAGAGCTACAAGTTCCAACAGATGAGACG GATTTTGTTTGTTTTGATGGAGGAAGAGATGATTTTCATAATTATAATGTAGAAGAACTT TTAGGGTTTTTGGAACTGTACAATTCTGCAGCTACAGATTCTGAGAAAGCTGTAGAAAAA ACTTTACAGGATATGGAAAAAAACCCTGAATTATCTAAGGAAAGGGAACCTGAACCTGAA CCAGTAGAAGCCAACTCAGAGGAAAGTGATAGTGTATTCTCAGAAAACACTGAGGATCTT CAGGAACAGTTTACAACTCAGAAGCACCACTCCCATGCAAACAGCCAAGCAAATCATGCT CAGGGAGAGCAGGCTTCATTTGAATCTTTTGAAGAAATGCTGCAAGATAAACTAAAAGTG CCAGAAAGTGAAAACAACAAAACCAGCAATAGTTCTCAGGTCTCAAATGAACAGGATAAG ATTGATGCCTATAAACTTTTGAAAAAAGAAATGACTCTAGACTTGAAAACCAAATTTGGC TCAACAGCTGATGCACTTGTATCTGATGATGAGACAACCAGACTCGTTACTTCATTAGAA GATGATTTTGATGAGGAATTGGATACTGAGTATTATGCAGTTGGAAAGGAAGATGAGGAG AACCAAGAAGACTTTGATGAGTTGCCATTACTTACCTTTACAGATGGGGAAGATATGAAA ACTCCAGCAAAGTCTGGCGTTGAGAAATATCCAACAGATAAAGAGCAGAATTCAAATGAA GAGGACAAGGTTCAGCTAACTGTGCCCCCTGGCATCAAAAATGATGATAAAAATATACTA ACAACCTGGGGGGACACTATCTTCTCTATTGTCACAGGAGGTGAAGAAACAAGAGATACG ATGGATTTAGAGAGCTCTAGTTCAGAGGAAGAAAAAGAAGATGATGATGATGCATTAGTC CCAGATAGCAAACAGGGGAAACCACAGTCAGCAACAGATTATAGTGACCCTGACAATGTA GATGATGGTCTTTTTATTGTAGACATTCCTAAAACAAATAATGACAAAGAAGTAAACGCA GAACATCACATTAAAGGAAAAGGGAGGGGAGTTCAGGAATCCAAGAGGGGCCTGGTACAA GATAAGACAGAATTAGAGGATGAAAATCAAGAAGGCATGACTGTGCACAGTTCTGTTCAC AGCAATAACCTCAACTCTATGCCAGCTGCTGAAAAGGGTAAAGACACATTAAAATCAGCT TATGATGATACAGAAAATGACCTAAAAGGAGCAGCTATTCATATCTCAAAAGGAATGCTC CACGAAGAAAAGCCTGGAGAGCAGATTTTGGAAGGTGGCTCAGAGAGTGAATCTGCACAG AAAGCTGCAGGGAATCAAATGAATGACAGAAAGATTCAACAGGAATCCCTGGGTAGTGCA CCACTCATGGGAGATGACCACCCTAACGCATCCAGAGACAGTGTGGAGGGAGACGCTTTG GTAAATGGGGCCAAACTGCACACGCTTTCAGTGGAGCATCAACGTGAGGAATTGAAAGAG GAATTAGTTCTTAAAACTCAAAACCAACCTAGATTCTCCTCTCCAGATGAGATTGATTTG CCCAGAGAACTGGAAGACGAGGTTCCCATTCTGGGAAGAAATCTTCCCTGGCAACAAGAA AGAGATGTGGCTGCCACAGCCAGTAAGCAAATGAGTGAGAAGATAAGGCTCTCTGAGGGA GAAGCCAAAGAGGACTCCTTGGATGAAGAGTTTTTTCATCACAAGGCAATGCAGGGCACA GAGGTAGGACAGACAGACCAAACTGACAGCACAGGAGGACCAGCTTTCCTTTCTAAAGTA GAAGAGGATGATTATCCCTCTGAAGAACTACTAGAGGATGAAAACGCTATAAATGCAAAA CGGTCTAAAGAAAAAAACCCTGGGAATCAGGGCAGGCAGTTTGATGTTAATCTGCAAGTC CCTGACAGAGCAGTTTTAGGGACCATTCATCCAGATCCAGAAATTGAAGAAAGCAAGCAA GAAACTAGTATGATTTTGGATAGCGAAAAAACAAGTGAGACTGCTGCCAAAGGGGTCAAC ACAGGAGGCAGGGAACCAAATACAATGGTGGAAAAAGAACGCCCTCTGGCAGATAAGAAA GCACAGAGACCATTTGAACGAAGTGACTTTTCTGACAGCATAAAAATTCAGACTCCAGAA TTAGGTGAAGTGTTTCAGAATAAAGATTCTGATTATCTGAAGAACGACAACCCTGAGGAA CATCTGAAGACCTCAGGGCTTGCAGGGGAGCCTGAGGGAGAACTCTCAAAAGAGGACCAT GAGAACACAGAGAAGTACATGGGCACAGAAAGCCAGGGGTCTGCTGCTGCAGAACCTGAA GATGACTCGTTCCACTGGACTCCACATACAAGTGTAGAGCCAGGGCATAGTGACAAGAGG GAGGACTTACTTATCATAAGCAGCTTCTTTAAAGAACAACAGTCTTTGCAGCGGTTCCAG AAGTACTTTAATGTCCATGAGCTGGAAGCCTTGCTACAAGAAATGTCATCAAAACTGAAG TCAGCGCAGCAGGAGAGCCTGCCCTATAATATGGAAAAAGTCCTAGATAAGGTCTTCCGT GCTTCTGAGTCACAAATTCTGAGCATAGCAGAAAAAATGCTTGATACTCGTGTGGCTGAA AATAGAGATCTGGGAATGAACGAAAATAACATATTTGAAGAGGCTGCAGTGCTTGATGAC ATTCAAGACCTCATCTATTTTGTCAGGTACAAGCACTCCACAGCAGAGGAGACAGCCACA CTGGTGATGGCACCACCTCTAGAGGAAGGCTTGGGTGGAGCAATGGAAGAGATGCAACCA CTGCATGAAGATAATTTCTCACGAGAGAAGACAGCAGAACTTAATGTGCAGGTTCCTGAA GAACCCACCCACTTGGACCAACGTGTGATTGGGGACACTCATGCCTCAGAAGTGTCACAG AAGCCAAATACTGAGAAAGACCTGGACCCAGGGCCAGTTACAACAGAAGACACTCCTATG GATGCTATTGATGCAAACAAGCAACCAGAGACAGCCGCCGAAGAGCCGGCAAGTGTCACA CCTTTGGAAAACGCAATCCTTCTAATATATTCATTCATGTTTTATTTAACTAAGTCGCTA GTTGCTACATTGCCTGATGATGTTCAGCCTGGGCCTGATTTTTATGGACTGCCATGGAAA CCTGTATTTATCACTGCCTTCTTGGGAATTGCTTCGTTTGCCATTTTCTTATGGAGAACT GTCCTTGTTGTGAAGGATAGAGTATATCAAGTCACGGAACAGCAAATTTCTGAGAAGTTG AAGACTATCATGAAAGAAAATACAGAACTTGTACAAAAATTGTCAAATTATGAACAGAAG ATCAAGGAATCAAAGAAACATGTTCAGGAAACCAGGAAACAAAATATGATTCTCTCTGAT GAAGCAATTAAATATAAGGATAAAATCAAGACACTTGAAAAAAATCAGGAAATTCTGGAT GACACAGCTAAAAATCTTCGTGTTATGCTAGAATCTGAGAGAGAACAGAATGTCAAGAAT CAGGACTTGATATCAGAAAACAAGAAATCTATAGAGAAGTTAAAGGATGTTATTTCAATG AATGCCTCAGAATTTTCAGAGGTTCAGATTGCACTTAATGAAGCTAAGCTTAGTGAAGAG AAGGTGAAGTCTGAATGCCATCGGGTTCAAGAAGAAAATGCTAGGCTTAAGAAGAAAAAA GAGCAGTTGCAGCAGGAAATCGAAGACTGGAGTAAATTACATGCTGAGCTCAGTGAGCAA ATCAAATCATTTGAGAAGTCTCAGAAAGATTTGGAAGTAGCTCTTACTCACAAGGATGAT AATATTAATGCTTTGACTAACTGCATTACACAGTTGAATCTGTTAGAGTGTGAATCTGAA TCTGAGGGTCAAAATAAAGGTGGAAATGATTCAGATGAATTAGCAAATGGAGAAGTGGGA GGTGACCGGAATGAGAAGATGAAAAATCAAATTAAGCAGATGATGGATGTCTCTCGGACA CAGACTGCAATATCGGTAGTTGAAGAGGATCTAAAGCTTTTACAGCTTAAGCTAAGAGCC TCCGTGTCCACTAAATGTAACCTGGAAGACCAGGTAAAGAAATTGGAAGATGACCGCAAC TCACTACAAGCTGCCAAAGCTGGACTGGAAGATGAATGCAAAACCTTGAGGCAGAAAGTG GAGATTCTGAATGAGCTCTATCAGCAGAAGGAGATGGCTTTGCAAAAGAAACTGAGTCAA GAAGAGTATGAACGGCAAGAAAGAGAGCACAGGCTGTCAGCTGCAGATGAAAAGGCAGTT TCGGCTGCAGAGGAAGTAAAAACTTACAAGCGGAGAATTGAAGAAATGGAGGATGAATTA CAGAAGACAGAGCGGTCATTTAAAAACCAGATCGCTACCCATGAGAAGAAAGCTCATGAA AACTGGCTCAAAGCTCGTGCTGCAGAAAGAGCTATAGCTGAAGAGAAAAGGGAAGCTGCC AATTTGAGACACAAATTATTAGAATTAACACAAAAGATGGCAATGCTGCAAGAAGAACCT GTGATTGTAAAACCAATGCCAGGAAAACCAAATACACAAAACCCTCCACGGAGAGGTCCT CTGAGCCAGAATGGCTCTTTTGGCCCATCCCCTGTGAGTGGTGGAGAATGCTCCCCTCCA TTGACAGTGGAGCCACCCGTGAGACCTCTCTCTGCTACTCTCAATCGAAGAGATATGCCT AGAAGTGAATTTGGATCAGTGGACGGGCCTCTACCTCATCCTCGATGGTCAGCTGAGGCA TCTGGGAAACCCTCTCCTTCTGATCCAGGATCTGGTACAGCTACCATGATGAACAGCAGC TCAAGAGGCTCTTCCCCTACCAGGGTACTCGATGAAGGCAAGGTTAATATGGCTCCAAAA GGGCCCCCTCCTTTCCCAGGAGTCCCTCTCATGAGCACCCCCATGGGAGGCCCTGTACCA CCACCCATTCGATATGGACCACCACCTCAGCTCTGCGGACCTTTTGGGCCTCGGCCACTT CCTCCACCCTTTGGCCCTGGTATGCGTCCACCACTAGGCTTAAGAGAATTTGCACCAGGC GTTCCACCAGGAAGACGGGACCTGCCTCTCCACCCTCGGGGATTTTTACCTGGACACGCA CCATTTAGACCTTTAGGTTCACTTGGCCCAAGAGAGTACTTTATTCCTGGTACCCGATTA CCACCCCCAACCCATGGTCCCCAGGAATACCCACCACCACCTGCTGTAAGAGACTTACTG CCGTCAGGCTCTAGAGATGAGCCTCCACCTGCCTCTCAGAGCACTAGCCAGGACTGTTCA CAGGCTTTAAAACAGAGCCCA |
| Restriction Sites | Please inquire |
| ACCN | NM_198551 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_198551.2, NP_940953.2 |
| RefSeq Size | 8123 bp |
| RefSeq ORF | 5724 bp |
| Locus ID | 375056 |
| UniProt ID | Q5JRA6 |
| Gene Summary | Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. This protein is required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers. It may participate in cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete COL7A1. It is also specifically required for the secretion of lipoproteins by participating in their export from the endoplasmic reticulum (PubMed:27138255, PubMed:19269366). Required for correct assembly of COPII coat components at endoplasmic reticulum exit sites (ERES) and for the localization of SEC16A and membrane-bound ER-resident complexes consisting of MIA2 and PREB/SEC12 to ERES (PubMed:28442536).[UniProtKB/Swiss-Prot Function] |
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