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Pellino 2 (PELI2) (NM_021255) Human Untagged Clone
CAT＃: SC319321
PELI2 (untagged)-Human pellino homolog 2 (Drosophila) (PELI2)
CNY 5,488.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_021255.2
GGCGCTCAGCGCAGGCAGGTCCCCCTGCTGCCGGGTCCCATTTGTTGCCGGCTCTGACTC
GGGGCGGCCGCGGCGCGCGGAGCTCCGGGGAGTCAGGCGGAGCAGCCGCGCAGCCACGAC GGAGCAGCAGCGGGACTGGCCGCCCCGCGCCCCCTTCGCCGCCGTGCCCTTCCCCGGCGC GCTCACCCCGTTCTCGGGATGGGATTGTAGCGGCGGCGCGGACTCGGCGGGGATCGCGGC GGAGGCGGCGGCGTCGGCGGCGGCGTCGGCGGCCGAGCGGGGCTCCATGTTTTCCCCTGG CCAGGAGGAACACTGCGCCCCCAATAAGGAGCCAGTGAAATACGGGGAGCTGGTGGTGCT CGGGTACAATGGTGCTTTACCCAATGGAGATAGAGGACGGAGGAAAAGTAGATTTGCCCT CTACAAGCGGCCCAAGGCAAATGGTGTCAAACCCAGCACCGTCCATGTGATATCCACGCC CCAGGCATCCAAGGCTATCAGCTGCAAAGGTCAACACAGTATATCCTACACTTTGTCAAG GAATCAGACTGTGGTGGTGGAGTACACACATGATAAGGATACGGATATGTTTCAGGTGGG CAGATCAACAGAAAGCCCTATCGACTTCGTTGTCACAGACACGATTTCTGGCAGCCAGAA CACGGACGAAGCCCAGATCACACAGAGCACCATATCCAGGTTCGCCTGCAGGATCGTGTG CGACAGGAATGAACCTTACACAGCACGGATATTCGCCGCCGGATTTGACTCTTCCAAAAA CATATTTCTTGGAGAAAAGGCAGCAAAGTGGAAAAACCCCGACGGCCACATGGATGGGCT CACTACTAATGGCGTCCTGGTGATGCATCCACGAGGGGGCTTCACCGAGGAGTCCCAGCC CGGGGTCTGGCGCGAGATCTCTGTCTGTGGAGATGTGTACACCTTGCGAGAAACCAGGTC GGCCCAGCAACGAGGAAAGCTGGTGGAAAGTGAGACCAACGTCCTGCAGGACGGCTCCCT CATTGACCTGTGTGGGGCCACTCTCCTCTGGAGAACAGCAGATGGGCTTTTTCATACTCC AACTCAGAAGCACATAGAAGCCCTCCGGCAGGAGATTAACGCCGCCCGGCCTCAGTGTCC TGTGGGGCTCAACACCCTGGCCTTCCCCAGCATCAACAGGAAAGAGGTGGTGGAGGAGAA GCAGCCCTGGGCATATCTCAGTTGTGGCCACGTGCACGGGTACCACAACTGGGGCCATCG GAGTGACACGGAGGCCAACGAGAGGGAGTGTCCCATGTGCAGGACTGTGGGCCCCTATGT GCCTCTCTGGCTTGGCTGTGAGGCAGGATTTTATGTAGACGCAGGACCGCCAACTCATGC TTTCACTCCCTGTGGACACGTGTGCTCGGAGAAGTCTGCAAAATACTGGTCTCAGATCCC GTTGCCTCATGGAACTCATGCATTTCACGCTGCTTGCCCTTTCTGTGCTACACAGCTGGT TGGGGAGCAAAACTGCATCAAATTAATTTTCCAAGGTCCAATTGACTGACGCCCTTGACA GCCATCTACGACTTTATTAACAGGTTACTGTGAAGATTTTGCCACTAACTCTAGATTTTA CCTTTTTGTAATGCTGTTTATCAGAGGAGGGTGACAGGGGCTGGAAATAAAGAGAGGGGA CATGGTGATGAAACATGGCAGGAGTGTAACAGATACCAGTGGTGTGTTGCATGCTCAAAA CAGCAGCGTCGTCATTGAAGTCTGCTTGATTAAACCATAATATCTTTGTAATAAAAAAAA AAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_021255 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_021255.2, NP_067078.1 |
| RefSeq Size | 5755 bp |
| RefSeq ORF | 1263 bp |
| Locus ID | 57161 |
| UniProt ID | Q9HAT8 |
| Domains | Pellino |
| Protein Families | Druggable Genome |
| Gene Summary | E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly 'Lys-48'-linked ubiquitination. May be important for LPS- and IL1B-induced MAP3K7-dependent, but not MAP3K3-dependent, NF-kappa-B activation. Can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203409 | PELI2 (Myc-DDK-tagged)-Human pellino homolog 2 (Drosophila) (PELI2) |
CNY 5,488.00 |
|
| RC203409L1 | Lenti ORF clone of Human pellino homolog 2 (Drosophila) (PELI2), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC203409L2 | Lenti ORF clone of Human pellino homolog 2 (Drosophila) (PELI2), mGFP tagged |
CNY 5,890.00 |
|
| RC203409L3 | Lenti ORF clone of Human pellino homolog 2 (Drosophila) (PELI2), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC203409L4 | Lenti ORF clone of Human pellino homolog 2 (Drosophila) (PELI2), mGFP tagged |
CNY 5,890.00 |
|
| RG203409 | PELI2 (tGFP-tagged) - Human pellino homolog 2 (Drosophila) (PELI2) |
CNY 7,088.00 |
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