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CCR4 (NM_005508) Human Untagged Clone
CAT＃: SC319943
CCR4 (untagged)-Human chemokine (C-C motif) receptor 4 (CCR4)
CNY 3,656.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CC-CKR-4; CD194; ChemR13; CKR4; CMKBR4; HGCN:14099; K5-5 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_005508.4
GCTCACAGGAAGCCACGCACCCTTGAAAGGCACCGGGTCCTTCTTAGCATCGTGCTTCCT
GAGCAAGCCTGGCATTGCCTCACAGACCTTCCTCAGAGCCGCTTTCAGAAAAGCAAGCTG CTTCTGGTTGGGCCCAGACCTGCCTTGAGGAGCCTGTAGAGTTAAAAAATGAACCCCACG GATATAGCAGACACCACCCTCGATGAAAGCATATACAGCAATTACTATCTGTATGAAAGT ATCCCCAAGCCTTGCACCAAAGAAGGCATCAAGGCATTTGGGGAGCTCTTCCTGCCCCCA CTGTATTCCTTGGTTTTTGTATTTGGTCTGCTTGGAAATTCTGTGGTGGTTCTGGTCCTG TTCAAATACAAGCGGCTCAGGTCCATGACTGATGTGTACCTGCTCAACCTTGCCATCTCG GATCTGCTCTTCGTGTTTTCCCTCCCTTTTTGGGGCTACTATGCAGCAGACCAGTGGGTT TTTGGGCTAGGTCTGTGCAAGATGATTTCCTGGATGTACTTGGTGGGCTTTTACAGTGGC ATATTCTTTGTCATGCTCATGAGCATTGATAGATACCTGGCAATTGTGCACGCGGTGTTT TCCTTGAGGGCAAGGACCTTGACTTATGGGGTCATCACCAGTTTGGCTACATGGTCAGTG GCTGTGTTCGCCTCCCTTCCTGGCTTTCTGTTCAGCACTTGTTATACTGAGCGCAACCAT ACCTACTGCAAAACCAAGTACTCTCTCAACTCCACGACGTGGAAGGTTCTCAGCTCCCTG GAAATCAACATTCTCGGATTGGTGATCCCCTTAGGGATCATGCTGTTTTGCTACTCCATG ATCATCAGGACCTTGCAGCATTGTAAAAATGAGAAGAAGAACAAGGCGGTGAAGATGATC TTTGCCGTGGTGGTCCTCTTCCTTGGGTTCTGGACACCTTACAACATAGTGCTCTTCCTA GAGACCCTGGTGGAGCTAGAAGTCCTTCAGGACTGCACCTTTGAAAGATACTTGGACTAT GCCATCCAGGCCACAGAAACTCTGGCTTTTGTTCACTGCTGCCTTAATCCCATCATCTAC TTTTTTCTGGGGGAGAAATTTCGCAAGTACATCCTACAGCTCTTCAAAACCTGCAGGGGC CTTTTTGTGCTCTGCCAATACTGTGGGCTCCTCCAAATTTACTCTGCTGACACCCCCAGC TCATCTTACACGCAGTCCACCATGGATCATGATCTCCATGATGCTCTGTAGAAAAATGAA ATGGTGAAATGCAGAGTCAATGAACTTTCCACATTCAGAGCTTACTTAAAATTGTATTTT AGTAAGAGATTCCTGAGCCAGTGTCAGGAGGAAGGCTTACACCCACAGTGGAAAGACAGC TTCTCATCCTGCAGGCAGCTTTTTCTCTCCCACTAGACAAGTCCAGCCTGGCAAGGGTTC ACCTGGGCTGAGGCATCCTTCCTCACACCAGGCTTGCCTGCAGGCATGAGTCAGTCTGAT GAGAACTCTGAGCAGTGCTTGAATGAAGTTGTAGGTAATATTGCAAGGCAAAGACTATTC CCTTCTAACCTGAACTGATGGGTTTCTCCAGAGGGAATTGCAGAGTACTGGCTGATGGAG TAAATCGCTACCTTTTGCTGTGGCAAATGGGCCCTCTAATTAATTTCTTGCTTTTGCGGA ACAATATAGATAACTGTTTTTCTAATAACATATCTCAGGCAAAGTATATTCCATTGAGCC AGATGTATGAAGAAACAATTAGTGAAGTGATGAAACCAGATCTCAATTATTTATTGTAAA GGATTATCTGTTAATTGAAACCAAACTTTTTATACTGATATAAGGGTAAGGATATGAAGA CATTAGCCAAGGTCTGCTTTCCAAACGTGAACTACAAGGCATTCAAAATCCAAACATATT TATGAAAATTCAAACACAGTTTCTCACTTGTTTGTGGACATGTTTTGTTCTAATTTTAAC AGAGGAATATTAAAAAATTTTAAATAGGCTGGGATTACAGGTGTGAGCCATCACGCCCGG CCACTTGTTTATTTTTTATTTTATTTTATTTTATTTTTGAGATGGAGTCTCACTCTGTCA CCCAAGCTGGAGTGCAGTGGCACTCGGTTCACTGCAAAGTCTGCCTCCCAGGTTCAAGCG ATTCTCCTGCCTCAGCTTCTCAAGCAGCTGGGATTAGAGGTGTGCACCACTACGCCAGGC TAGTTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTAGTCTTGAAC TCCTGACCTCAGGTGATCTGCCTGCTTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGA GCCACCTCGCCCAGCCAAGGTCTTTTACTTGTTTATAAACAGTCTCTTCATAATTAAAAT TAAGGATTAATAAAGTATGACAATACCTCCTTAATCATTTTGAAGTGCCTGCTATCAATT GAAATAAAAACAATCAACCAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_005508 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005508.4, NP_005499.1 |
| RefSeq Size | 1657 bp |
| RefSeq ORF | 1083 bp |
| Locus ID | 1233 |
| UniProt ID | P51679 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Chemokine signaling pathway, Cytokine-cytokine receptor interaction |
| Gene Summary | The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. [provided by RefSeq, Jul 2008] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
The Lupane-type Triterpene 30-Oxo-calenduladiol Is a CCR5 Antagonist with Anti-HIV-1 and Anti-chemotactic Activities
,Jonathan Barroso-González, Nabil El Jaber-Vazdekis, Laura García-Expósito, José-David Machado, Rafael Zárate, Ángel G. Ravelo, Ana Estévez-Braun, and Agustín Valenzuela-Fernández,
J. Biol. Chem., Jun 2009; 284: 16609 - 16620.
[CCR4]
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Molecular Interaction of a Potent Nonpeptide Agonist with the Chemokine Receptor CCR8
,PC Jensen, R Nygaard, S Thiele, A Elder, G Zhu, R Kolbeck, S Ghosh, TW Schwartz, and MM Rosenkilde,
Mol Pharmacol. 2007 Aug;72(2):327-40.
[CCR4]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210003 | CCR4 (Myc-DDK-tagged)-Human chemokine (C-C motif) receptor 4 (CCR4) |
CNY 3,656.00 |
|
| RC210003L1 | Lenti ORF clone of Human chemokine (C-C motif) receptor 4 (CCR4), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC210003L2 | Lenti ORF clone of Human chemokine (C-C motif) receptor 4 (CCR4), mGFP tagged |
CNY 6,056.00 |
|
| RC210003L3 | Lenti ORF clone of Human chemokine (C-C motif) receptor 4 (CCR4), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC210003L4 | Lenti ORF clone of Human chemokine (C-C motif) receptor 4 (CCR4), mGFP tagged |
CNY 6,056.00 |
|
| RG210003 | CCR4 (tGFP-tagged) - Human chemokine (C-C motif) receptor 4 (CCR4) |
CNY 5,256.00 |
