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LILRB1 (NM_001081639) Human Untagged Clone
CAT＃: SC320409
LILRB1 (untagged)-Human leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 (LILRB1), transcript variant 4
CNY 4,856.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD85J; ILT-2; ILT2; LIR-1; LIR1; MIR-7; MIR7; PIR-B; PIRB |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_001081639 edited
GAGGAGGAACAGAAAAGAAAAGAAAAGAAAAAGTGGGAAACAAATAATCTAAGAATGAGG AGAAAGCAAGAAGAGTGACCCCCTTGTGGGCACTCCATTGGTTTTATGGCGCCTCTACTT TCTGGAGT:TTGTGTAAAACAAAAATATTATGGTCTTTGTGCACATTTACATCAAGCTCA GCCTGGGCGGCACAGCCAGATGCGAGATGCGTCTCTGCTGATCTGAGTCTGCCTGCAGCA TGGACCTGGGTCTTCCCTGAAGCATCTCCAGGGCTGGAGGGACGACTGCCATGCACCGAG GGCTCATCCATCCACAGAGCAGGGCAGTGGGAGGAGACGCCATGACCCCCATCCTCACGG TCCTGATCTGTCTCGGGCTGAGTCTGGGCCCCCGGACCCACGTGCAGGCAGGGCACCTCC CCAAGCCCACCCTCTGGGCTGAACCAGGCTCTGTGATCACCCAGGGGAGTCCTGTGACCC TCAGGTGTCAGGGGGGCCAGGAGACCCAGGAGTACCGTCTATATAGAGAAAAGAAAACAG CACCCTGGATTACACGGATCCCACAGGAGCTTGTGAAGAAGGGCCAGTTCCCCATCCCAT CCATCACCTGGGAACATGCAGGGCGGTATCGCTGTTACTATGGTAGCGACACTGCAGGCC GCTCAGAGAGCAGTGACCCCCTGGAGCTGGTGGTGACAGGAGCCTACATCAAACCCACCC TCTCAGCCCAGCCCAGCCCCGTGGTGAACTCAGGAGGGAATGTAACCCTCCAGTGTGACT CACAGGTGGCATTTGATGGCTTCATTCTGTGTAAGGAAGGAGAAGATGAACACCCACAAT GCCTGAACTCCCAGCCCCATGCCCGTGGGTCGTCCCGCGCCATCTTCTCCGTGGGCCCCG TGAGCCCGAGTCGCAGGTGGTGGTACAGGTGCTATGCTTATGACTCGAACTCTCCCTATG AGTGGTCTCTACCCAGTGATCTCCTGGAGCTCCTGGTCCTAGGTGTTTCTAAGAAGCCAT CACTCTCAGTGCAGCCAGGTCCTATCGTGGCCCCTGAGGAGACCCTGACTCTGCAGTGTG GCTCTGATGCTGGCTACAACAGATTTGTTCTGTATAAGGACGGGGAACGTGACTTCCTTC AGCTCGCTGGCGCACAGCCCCAGGCTGGGCTCTCCCAGGCCAACTTCACCCTGGGCCCTG TGAGCCGCTCCTACGGGGGCCAGTACAGATGCTACGGTGCACACAACCTCTCCTCCGAGT GGTCGGCCCCCAGCGACCCCCTGGACATCCTGATCGCAGGACAGTTCTATGACAGAGTCT CCCTCTCGGTGCAGCCGGGCCCCACGGTGGCCTCAGGAGAGAACGTGACCCTGCTGTGTC AGTCACAGGGATGGATGCAAACTTTCCTTCTGACCAAGGAGGGGGCAGCTGATGACCCAT GGCGTCTAAGATCAACGTACCAATCTCAAAAATACCAGGCTGAATTCCCCATGGGTCCTG TGACCTCAGCCCATGCGGGGACCTACAGGTGCTACGGCTCACAGAGCTCCAAACCCTACC TGCTGACTCACCCCAGTGACCCCCTGGAGCTCGTGGTCTCAGGACCGTCTGGGGGCCCCA GCTCCCCGACAACAGGCCCCACCTCCACATCTGGCCCTGAGGACCAGCCCCTCACCCCCA CCGGGTCGGATCCCCAGAGTGGTCTGGGAAGGCACCTGGGGGTTGTGATCGGCATCTTGG TGGCCGTCATCCTACTGCTCCTCCTCCTCCTCCTCCTCTTCCTCATCCTCCGACATCGAC GTCAGGGCAAACACTGGACATCGACCCAGAGAAAGGCTGATTTCCAACATCCTGCAGGGG CTGTGGGGCCAGAGCCCACAGACAGAGGCCTGCAGTGGAGGTCCAGCCCAGCTGCCGATG CCCAGGAAGAAAACCTCTATGCTGCCGTGAAGCACACACAGCCTGAGGATGGGGTGGAGA TGGACACTC:G::GAGCCCACACGATGAAGACCCCCAGGCAGTGACGTATGCCGAGGTGA AACACTCCAGACCTAGGAGAGAAATGGCCTCTCCTCCTTCCCCACTGTCTGGGGAATTCC TGGACACAAAGGACAGACAGGCGGAAGAGGACAGGCAGATGGACACTGAGGCTGCTGCAT CTGAAGCCCCCCAGGATGTGACCTACGCCCAGCTGCACAGCTTGACCCTTAGACGGAAGG CAACTGAGCCTCCTCCATCCCAGGAAGGGCCCTCTCCAGCTGTGCCCAGCATCTACGCCA CTCTGGCCATCCACTAGCCCAGGGGGGGACGCAGACCCCACACTCCATGGAGTCTGGAAT GCATGGGAGCTGCCCCCCCAGTGGACACCATTGGACCCCACCCAGCCTGGATCTACCCCA GGAGACTCTGGGAACTTTTAGGGGTCACTCAATTCTGCAGTATAAATAACTAATGTCTCT ACAATTTTGAAATAAAGCAACAGACTTCTCAATAATCAATGAAGTAGCTGAGAAAACTAA GTCAGAAAGTGCATTAAACTGAATCACAATGTAAATATTACACATCAAGCGATGAAACTG GAAAACTACAAGCCACGAATGAATGAATTAGGAAAGAAAAAAAGTAGGAAATGAATGATC TTGGCTTTCCTATAAGAAATTTAGGGCAGGGCACGGTGGCTCACGCCTGTAATTCCAGCA CTTTGGGAGGCCGAGGCGGGCAGATCACGAGTTCAGGAGATCGAGACCATCTTGGCCAAC ATGGTGAAACCCTGTCTCTCCTAAAAATACAAAAATTAGCTGGATGTGGTGGCAGTGCCT GTAATCCCAGCTATTTGGGAGGCTGAGGCAGGAGAATCGCTTGAACCAGGGAGTCAGAGG TTTCAGTGAGCCAAGATCGCACCACTGCTCTCCAGCCTGGCGACAGAGGGAGACTCCATC TCAAATTAAAAAAAAAAAAAAAAAAGAAAGAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_001081639 |
| Insert Size | 3200 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001081639.1, NP_001075108.1 |
| RefSeq Size | 2859 bp |
| RefSeq ORF | 1956 bp |
| Locus ID | 10859 |
| UniProt ID | Q8NHL6 |
| Protein Families | Transmembrane |
| Gene Summary | This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (4) uses an alternate in-frame splice site in the 3' coding region and differs in the 5' UTR, compared to variant 1. The resulting protein (isoform 4) is longer, compared to isoform 1. Sequence Note: A downstream translational start codon is selected for this RefSeq based on its better conservation in mammalian species and on the presence of a predicted signal peptide in the protein N-terminus. An upstream in-frame start codon is also present but is only conserved in primates, and use of the upstream start codon would result in a protein that is 17 aa longer at the N-terminus and lacks a predicted signal peptide. Leaky scanning by ribosomes may allow translation initiation at the downstream start codon. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204840 | LILRB1 (Myc-DDK-tagged)-Human leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 (LILRB1), transcript variant 4 |
CNY 3,990.00 |
|
| RC204840L3 | Lenti-ORF clone of LILRB1 (Myc-DDK-tagged)-Human leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 (LILRB1), transcript variant 4 |
CNY 5,890.00 |
|
| RC204840L4 | Lenti-ORF clone of LILRB1 (mGFP-tagged)-Human leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 (LILRB1), transcript variant 4 |
CNY 5,890.00 |
|
| RG204840 | LILRB1 (tGFP-tagged) - Human leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 (LILRB1), transcript variant 4 |
CNY 4,370.00 |
|
| SC316013 | LILRB1 (untagged)-Human leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 (LILRB1), transcript variant 4 |
CNY 7,220.00 |
