United States
Germany
Japan
United Kingdom
China
TEM8 (ANTXR1) (NM_018153) Human Untagged Clone
CAT＃: SC321448
ANTXR1 (untagged)-Human anthrax toxin receptor 1 (ANTXR1), transcript variant 3
CNY 5,488.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ATR; GAPO; TEM8 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_018153.2
GGGGAATAAAGGACCCGCGAGGAAGGGCCCGCGGATGGCGCGTCCCTGAGGGTCGTGGCG
AGTTCGCGGAGCGTGGGAAGGAGCGGACCCTGCTCTCCCCGGGCTGCGGGCCATGGCCAC GGCGGAGCGGAGAGCCCTCGGCATCGGCTTCCAGTGGCTCTCTTTGGCCACTCTGGTGCT CATCTGCGCCGGGCAAGGGGGACGCAGGGAGGATGGGGGTCCAGCCTGCTACGGCGGATT TGACCTGTACTTCATTTTGGACAAATCAGGAAGTGTGCTGCACCACTGGAATGAAATCTA TTACTTTGTGGAACAGTTGGCTCACAAATTCATCAGCCCACAGTTGAGAATGTCCTTTAT TGTTTTCTCCACCCGAGGAACAACCTTAATGAAACTGACAGAAGACAGAGAACAAATCCG TCAAGGCCTAGAAGAACTCCAGAAAGTTCTGCCAGGAGGAGACACTTACATGCATGAAGG ATTTGAAAGGGCCAGTGAGCAGATTTATTATGAAAACAGACAAGGGTACAGGACAGCCAG CGTCATCATTGCTTTGACTGATGGAGAACTCCATGAAGATCTCTTTTTCTATTCAGAGAG GGAGGCTAATAGGTCTCGAGATCTTGGTGCAATTGTTTACTGTGTTGGTGTGAAAGATTT CAATGAGACACAGCTGGCCCGGATTGCGGACAGTAAGGATCATGTGTTTCCCGTGAATGA CGGCTTTCAGGCTCTGCAAGGCATCATCCACTCAATTTTGAAGAAGTCCTGCATCGAAAT TCTAGCAGCTGAACCATCCACCATATGTGCAGGAGAGTCATTTCAAGTTGTCGTGAGAGG AAACGGCTTCCGACATGCCCGCAACGTGGACAGGGTCCTCTGCAGCTTCAAGATCAATGA CTCGGTCACACTCAATGAGAAGCCCTTTTCTGTGGAAGATACTTATTTACTGTGTCCAGC GCCTATCTTAAAAGAAGTTGGCATGAAAGCTGCACTCCAGGTCAGCATGAACGATGGCCT CTCTTTTATCTCCAGTTCTGTCATCATCACCACCACACACTGTAGCCTCCACAAAATTGC ATCAGGCCCCACAACAGCTGCTTGCATGGAATAGCAGAGAATACCGCCTGCTCCCTCCGG ACAGCACACTCCTGAAAACGGGGAGAGAGGAGCCAAACATGCTCGGTTTACACTTTCCTT ATTTACTGAATGAGTGGAGGGCAGAGACAGGCCTGGAGTTACGCACACTGAGTGCCCCAA CATGGAAAGAAACATCAGGAGGGACAGGAAACGTTCCCTCCTTAACCAACAGTTTTCAAG ACCTTACTGGAGGCACTTTATTGGCTACATAATCACTCCATGCGGTGGGCATCAGGCAGA ATCCTGGTGCAGACCCAACTTTGAGGTGGAGGATTTCACAGTTTCTTTATTTTGAACTTC CCCCAGGCTCCCACTAATTCCTCTCCATTCTATCCTCCTCCCTTTCCCACAAAAGAAAAC AGAAAGGAGCAGCAGTGTTTGATACCGTATCATCCAGAGGCCTGGTTCTCTCCCATTATA GGGCAAACAAGCCCTGGCAAGATATTTCACTCCCGCCCCATGCCATGCATTAAAAATCCA AAATTGCCTATATTCCACCTGCCAAGCAAGAGATGCTTTCATTATTGAAGTTCCAAATGT ATACCTTTGAGAACAGTGCCTTCTCGTCTTAAAAGAGAGGTCCTCATTTTGTGAGTTGGG AGCAGAGGGAATTAAAGAAAGCCATGATGCAGGGATTTGGCCATTCAAGCCGGGCAGCCT TCAGAGAATGTCATCCCTAATGACACATGCCCGAATGAAGGAGCGGGGCTGAGCTTGTCC TGCCTTCGTATTGAATGTTGCCTGTCTGCCTCCTTAATAGCGGGCCTCTGTGTGAGCATT TGACAAGACTTAAAACTATTCATTGAAGAAAATGGATGATCCCCCAACAGGAAGATGCAA CCCCATGGGCTGCCTGCTTGACCACAGAAGTGCTTCCAGCTCCAGTTGCTCATCTGAGAA CTCCCCCCACCACTTGCTGTTAAAATTGTTAAAATTAAAGGCCATGTTGATTGAAAAAAA AAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_018153 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_018153.2, NP_060623.2 |
| RefSeq Size | 2143 bp |
| RefSeq ORF | 1002 bp |
| Locus ID | 84168 |
| UniProt ID | Q9H6X2 |
| Domains | VWA |
| Protein Families | Druggable Genome, Transmembrane |
| Gene Summary | This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described. [provided by RefSeq, Oct 2008] Transcript Variant: This variant (3) has an alternative 3' coding region and 3' UTR segment and lacks multiple segments, compared to variant 1. The resulting protein (isoform 3) has a shorter and distinct C-terminus when it is compared to isoform 1. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204112 | ANTXR1 (Myc-DDK-tagged)-Human anthrax toxin receptor 1 (ANTXR1), transcript variant 3 |
CNY 3,600.00 |
|
| RC204112L1 | Lenti ORF clone of Human anthrax toxin receptor 1 (ANTXR1), transcript variant 3, Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC204112L2 | Lenti ORF clone of Human anthrax toxin receptor 1 (ANTXR1), transcript variant 3, mGFP tagged |
CNY 5,890.00 |
|
| RC204112L3 | Lenti ORF clone of Human anthrax toxin receptor 1 (ANTXR1), transcript variant 3, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC204112L4 | Lenti ORF clone of Human anthrax toxin receptor 1 (ANTXR1), transcript variant 3, mGFP tagged |
CNY 5,890.00 |
|
| RG204112 | ANTXR1 (tGFP-tagged) - Human anthrax toxin receptor 1 (ANTXR1), transcript variant 3 |
CNY 5,200.00 |
