United States
Germany
Japan
United Kingdom
China
HIPPI (IFT57) (NM_018010) Human Untagged Clone
CAT＃: SC321611
IFT57 (untagged)-Human intraflagellar transport 57 homolog (Chlamydomonas) (IFT57)
CNY 3,656.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ESRRBL1; HIPPI; MHS4R2; OFD18 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_018010.2
GTAACCGGTCGTGGCTGTACTGGCGGCGGCAGGGCTGGCGGCTTAGGCCGCAGAGGTCTG
TGGGCCTGAGCCCACGCTGGACTCTGTCCGTTCTGCGATGACTGCTGCTCTGGCCGTCGT CACGACGTCGGGTTTGGAAGATGGGGTGCCTAGGTCCCGTGGCGAAGGGACCGGGGAAGT GGTCTTGGAGCGGGGGCCCGGCGCGGCCTACCACATGTTCGTGGTGATGGAGGACTTGGT GGAGAAGCTGAAGCTGCTCCGCTACGAGGAGGAGTTCCTCCGGAAGAGCAACCTGAAGGC CCCGTCCAGACACTATTTTGCACTGCCTACCAACCCTGGCGAACAGTTCTACATGTTTTG TACTCTTGCTGCTTGGTTGATTAATAAAGCGGGACGTCCCTTTGAGCAGCCTCAAGAATA TGATGACCCTAATGCAACAATATCTAACATACTATCCGAGCTTCGGTCATTTGGAAGAAC TGCAGATTTTCCTCCTTCAAAATTAAAGTCAGGTTATGGAGAACATGTATGCTATGTTCT TGATTGCTTCGCTGAAGAAGCATTGAAATATATTGGTTTCACCTGGAAAAGGCCAATATA CCCAGTAGAAGAATTAGAAGAAGAAAGCGTTGCAGAAGATGATGCAGAATTAACATTAAA TAAAGTGGATGAAGAATTTGTGGAAGAAGAGACAGATAATGAAGAAAACTTTATTGATCT CAACGTTTTAAAGGCCCAGACATATCACTTGGATATGAACGAGACTGCCAAACAAGAAGA TATTTTGGAATCCACAACAGATGCTGCAGAATGGAGCCTAGAAGTGGAACGTGTACTACC GCAACTGAAAGTCACGATTAGGACTGACAATAAGGATTGGAGAATCCATGTTGACCAAAT GCACCAGCACAGAAGTGGAATTGAATCTGCTCTAAAGGAGACCAAGGGATTTTTGGACAA ACTCCATAATGAAATTACTAGGACTTTGGAAAAGATCAGCAGCCGAGAAAAGTACATCAA CAATCAGCTTGAGAATTTGGTTCAAGAATATCGTGCAGCTCAAGCCCAGCTGAGTGAGGC AAAGGAGCGATACCAGCAGGGAAATGGAGGAGTGACGGAAAGAACCAGACTCCTCTCTGA GGTTATGGAAGAATTAGAAAAGGTAAAACAAGAAATGGAAGAAAAGGGCAGCAGCATGAC TGATGGTGCTCCTTTGGTGAAGATTAAACAGAGCTTAACAAAACTGAAGCAAGAAACTGT AGAGATGGACATTAGAATTGGCATTGTGGAACACACACTACTCCAATCAAAGCTGAAGGA GAAGTCCAACATGACTAGGAACATGCATGCCACAGTTATTCCAGAACCAGCAACAGGCTT TTATTAAAACATACTGGTTTTCATGTTTCTGATTAGTTGGGTTTTTTATATCAAACTATA TTTCATGTTGCATAGATTTCAAAACATAATTTTATGTTCAATGGGTATTTTTTTACATAT ACATACTCACATATTATATCATGGTGATTATGATGGTTAAAGCCTTTACACTGAATGTAA TGTTTAATAAAGAAATTACAAATTCTCACTTTCAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_018010 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_018010.2, NP_060480.1 |
| RefSeq Size | 3052 bp |
| RefSeq ORF | 1290 bp |
| Locus ID | 55081 |
| UniProt ID | Q9NWB7 |
| Protein Families | Druggable Genome |
| Protein Pathways | Huntington's disease |
| Gene Summary | Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC204116 | IFT57 (Myc-DDK-tagged)-Human intraflagellar transport 57 homolog (Chlamydomonas) (IFT57) |
CNY 3,656.00 |
|
| RC204116L3 | Lenti ORF clone of Human intraflagellar transport 57 homolog (Chlamydomonas) (IFT57), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC204116L4 | Lenti ORF clone of Human intraflagellar transport 57 homolog (Chlamydomonas) (IFT57), mGFP tagged |
CNY 5,890.00 |
|
| RG204116 | IFT57 (tGFP-tagged) - Human intraflagellar transport 57 homolog (Chlamydomonas) (IFT57) |
CNY 5,256.00 |
