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SIGLEC5 (NM_003830) Human Untagged Clone
CAT＃: SC321803
SIGLEC5 (untagged)-Human sialic acid binding Ig-like lectin 5 (SIGLEC5)
CNY 6,168.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD33L2; CD170; OB-BP2; OBBP2; SIGLEC-5 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_003830.1
GCCGGACCTGGGACTGGGCTGGGGCCCTGGCGGATGGAGACATGCTGCCCCTGCTGCTGC
TGCCCCTGCTGTGGGGGGGGTCCCTGCAGGAGAAGCCAGTGTACGAGCTGCAAGTGCAGA AGTCGGTGACGGTGCAGGAGGGCCTGTGCGTCCTTGTGCCCTGCTCCTTCTCTTACCCCT GGAGATCCTGGTATTCCTCTCCCCCACTCTACGTCTACTGGTTCCGGGACGGGGAGATCC CATACTACGCTGAGGTTGTGGCCACAAACAACCCAGACAGAAGAGTGAAGCCAGAGACCC AGGGCCGATTCCGCCTCCTTGGGGATGTCCAGAAGAAGAACTGCTCCCTGAGCATCGGAG ATGCCAGAATGGAGGACACGGGAAGCTATTTCTTCCGCGTGGAGAGAGGAAGGGATGTAA AATATAGCTACCAACAGAATAAGCTGAACTTGGAGGTGACAGCCCTGATAGAGAAACCCG ACATCCACTTTCTGGAGCCTCTGGAGTCCGGCCGCCCCACAAGGCTGAGCTGCAGCCTTC CAGGATCCTGTGAAGCGGGACCACCTCTCACATTCTCCTGGACGGGGAATGCCCTCAGCC CCCTGGACCCCGAGACCACCCGCTCCTCGGAGCTCACCCTCACCCCCAGGCCCGAGGACC ATGGCACCAACCTCACCTGTCAGATGAAACGCCAAGGAGCTCAGGTGACCACGGAGAGAA CTGTCCAGCTCAATGTCTCCTATGCACCACAGACCATCACCATCTTCAGGAACGGCATAG CCCTAGAGATCCTGCAAAACACCTCATACCTTCCGGTCCTGGAGGGCCAGGCTCTGCGGC TGCTCTGTGATGCTCCCAGCAACCCCCCTGCACACCTGAGCTGGTTCCAGGGCTCCCCTG CCCTGAACGCCACCCCCATCTCCAATACCGGGATCTTGGAGCTTCGTCGAGTAAGGTCTG CAGAAGAAGGAGGCTTCACCTGCCGCGCTCAGCACCCGCTGGGCTTCCTGCAAATTTTTC TGAATCTCTCAGTTTACTCCCTCCCACAGTTGCTGGGCCCCTCCTGCTCCTGGGAGGCTG AGGGTCTGCACTGCAGATGCTCCTTTCGAGCCCGGCCGGCCCCCTCCCTGTGCTGGCGGC TTGAGGAGAAGCCGCTGGAGGGGAACAGCAGCCAGGGCTCATTCAAGGTCAACTCCAGCT CAGCTGGGCCCTGGGCCAACAGCTCCCTGATCCTCCACGGGGGGCTCAGCTCCGACCTCA AAGTCAGCTGCAAGGCCTGGAACATCTATGGGTCCCAGAGCGGCTCTGTCCTGCTGCTGC AAGGGAGATCGAACCTTGGGACAGGAGTGGTTCCTGCAGCCCTTGGTGGTGCTGGTGTCA TGGCCCTGCTCTGTATCTGTCTGTGCCTCATCTTCTTTTTAATAGTGAAAGCCCGCAGGA AGCAAGCAGCTGGGAGACCAGAGAAAATGGATGATGAAGACCCCATTATGGGTACCATCA CCTCGGGTTCCAGGAAGAAGCCCTGGCCAGACAGCGCCGGAGATCAAGCATCTCCTCCTG GGGATGCCCCTCCCTTGGAAGAACAAAAGGAGCTCCATTATGCCTCCCTTAGTTTTTCTG AGATGAAGTCGAGGGAGCCTAAGGACCAGGAGGCCCCAAGCACCACGGAGTACTCGGAGA TCAAGACAAGCAAGTGAGGATTTGCCCAGAGTTCAGTCCTGGCTGGAGGAGCCACAGCCT GTCTGGGGGAAAGGACAAGTCAGGGACCACTTGCTGAAGCACGAAGAGCCCTTGTGGCAA TGTTAACATTAACTGATGTTTAAGTGCTCCAAGCAGAGCAGAAAGAAAACAGATGATGGA ATTAGAGAGGTGGGCTCAAATCTAGGCCCTGGCACTGTCATCAAGCAATTCACTGCATCC CTCTGTGCCTCAGTTTCCCATTCTGTAAATCAGAGATCATGCATGCTACCTCAAAGGTTG TTGTGAACATTAAAGAAATCAACACATGGAAATCAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_003830 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003830.1, NP_003821.1 |
| RefSeq Size | 2130 bp |
| RefSeq ORF | 1656 bp |
| Locus ID | 8778 |
| UniProt ID | O15389 |
| Domains | ig |
| Protein Families | Druggable Genome, Transmembrane |
| Gene Summary | This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. [provided by RefSeq, Feb 2012] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206610 | SIGLEC5 (Myc-DDK-tagged)-Human sialic acid binding Ig-like lectin 5 (SIGLEC5) |
CNY 6,152.00 |
|
| RC206610L1 | Lenti ORF clone of Human sialic acid binding Ig-like lectin 5 (SIGLEC5), Myc-DDK-tagged |
CNY 8,552.00 |
|
| RC206610L2 | Lenti ORF clone of Human sialic acid binding Ig-like lectin 5 (SIGLEC5), mGFP tagged |
CNY 6,460.00 |
|
| RC206610L3 | Lenti ORF clone of Human sialic acid binding Ig-like lectin 5 (SIGLEC5), Myc-DDK-tagged |
CNY 8,552.00 |
|
| RC206610L4 | Lenti ORF clone of Human sialic acid binding Ig-like lectin 5 (SIGLEC5), mGFP tagged |
CNY 8,552.00 |
|
| RG206610 | SIGLEC5 (tGFP-tagged) - Human sialic acid binding Ig-like lectin 5 (SIGLEC5) |
CNY 7,752.00 |
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