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TBX21 (NM_013351) Human Untagged Clone
CAT＃: SC322597
TBX21 (untagged)-Human T-box 21 (TBX21)
CNY 5,984.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | T-bet; T-PET; TBET; TBLYM |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_013351 edited
GGACGCGTGGGCGAGGGCGTAGAAGCCAGGCGTCAGAGCCCGGGCTCCGGTGGGGTCCCC CACCCGGCCCTCGGGTCCCCCGCCCCCTGCTCCCTGCCCATCCCAGCCCACGCGACCCTC TCGCGCGCGGAGGGGCGGGTCCTCGACGGCTACGGGAAGGTGCCAGCCCGCCCCGGATGG GCATCGTGGAGCCGGGTTGCGGAGACATGCTGACGGGCACCGAGCCGATGCCGGGGAGCG ACGAGGGCCGGGCGCCTGGCGCCGACCCGCAGCACCGCTACTTCTACCCGGAGCCGGGCG CGCAGGACGCGGACGAGCGTCGCGGGGGCGGCAGCCTGGGGTCTCCCTACCCGGGGGGCG CCTTGGTGCCCGCCCCGCCGAGCCGCTTCCTTGGAGCCTACGCCTACCCGCCGCGACCCC AGGCGGCCGGCTTCCCCGGCGCGGGCGAGTCCTTCCCGCCGCCCGCGGACGCCGAGGGCT ACCAGCCGGGCGAGGGCTACGCCGCCCCGGACCCGCGCGCCGGGCTCTACCCGGGGCCGC GTGAGGACTACGCGCTACCCGCGGGACTGGAGGTGTCGGGGAAACTGAGGGTCGCGCTCA ACAACCACCTGTTGTGGTCCAAGTTTAATCAGCACCAGACAGAGATGATCATCACCAAGC AGGGACGGCGGATGTTCCCATTCCTGTCATTTACTGTGGCCGGGCTGGAGCCCACCAGCC ACTACAGGATGTTTGTGGACGTGGTCTTGGTGGACCAGCACCACTGGCGGTACCAGAGCG GCAAGTGGGTGCAGTGTGGAAAGGCCGAGGGCAGCATGCCAGGAAACCGCCTGTACGTCC ACCCGGACTCCCCCAACACAGGAGCGCACTGGATGCGCCAGGAAGTTTCATTTGGGAAAC TAAAGCTCACAAACAACAAGGGGGCGTCCAACAATGTGACCCAGATGATTGTGCTCCAGT CCCTCCATAAGTACCAGCCCCGGCTGCATATCGTTGAGGTGAACGACGGAGAGCCAGAGG CAGCCTGCAACGCTTCCAACACGCATATCTTTACTTTCCAAGAAACCCAGTTCATTGCCG TGACTGCCTACCAGAATGCCGAGATTACTCAGCTGAAAATTGATAATAACCCCTTTGCCA AAGGATTCCGGGAGAACTTTGAGTCCATGTACACATCTGTTGACACCAGCATCCCCTCCC CGCCTGGACCCAACTGTCAATTCCTTGGGGGAGATCACTACTCTCCTCTCCTACCCAACC AGTATCCTGTTCCCAGCCGCTTCTACCCCGACCTTCCTGGCCAGGCGAAGGATGTGGTTC CCCAGGCTTACTGGCTGGGGGCCCCCCGGGACCACAGCTATGAGGCTGAGTTTCGAGCAG TCAGCATGAAGCCTGCATTCTTGCCCTCTGCCCCTGGGCCCACCATGTCCTACTACCGAG GCCAGGAGGTCCTGGCACCTGGAGCTGGCTGGCCTGTGGCACCCCAGTACCCTCCCAAGA TGGGCCCGGCCAGCTGGTTCCGCCCTATGCGGACTCTGCCCATGGAACCCGGCCCTGGAG GCTCAGAGGGACGGGGACCAGAGGACCAGGGTCCCCCCTTGGTGTGGACTGAGATTGCCC CCATCCGGCCGGAATCCAGTGATTCAGGACTGGGCGAAGGAGACTCTAAGAGGAGGCGCG TGTCCCCCTATCCTTCCAGTGGTGACAGCTCCTCCCCTGCTGGGGCCCCTTCTCCTTTTG ATAAGGAAGCTGAAGGACAGTTTTATAACTATTTTCCCAACTGAGCAGATGACATGATGA AAGGAACAGAAACAGTGTTATTAGGTTGGAGGACACCGACTAATTTGGGAAACGGATGAA GGACTGAGAAGGCCCCCGCTCCCTCTGGCCCTTCTCTGTTTAGTAGTTGGTTGGGGAAGT GGGGCTCAAGAAGGATTTTGGGGTTCACCAGATGCTTCCTGGCCCACGATGAAACCTGAG AGGGGTGTCCCCTTGCCCCATCCTCTGCCCTAACTACAGTCGTTTACCTGGTGCTGCGTC TTGCTTTTGGTTTCCAGCTGGAGAAAAGAAGACAAGAAAGTCTTGGGCATGAAGGAGCTT TTTGCATCTAGTGGGTGGGAGGGGTCAGGTGTGGGACATGGGAGCAGGAGACTCCACTTT CTTCCTTTGTACAGTAACTTTCAACCTTTTCGTTGGCATGTGTGTTAATCCCTGATCCAA AAAGAACAAATACACGTATGTTATAACCATCAGCCCGCCAGGGTCAGGGAAAGGACTCAC CTGACTTTGGACAGCTGGCCTGGGCTCCCCCTGCTCAAACACAGTGGGGATCAGAGAAAA GGGGCTGGAAAGGGGGGAATGGCCCACATCTCAAGAAGCAAGATATTGTTTGTGGTGGTT GTGTGTGGGTGTGTGTTTTTTCTTTTTCTTTCTTTTTATTTTTTTTGAATGGGGGAGGCT ATTTATTGTACTGAGAGTGGTGTCTGGATATATTCCTTTTGTCTTCATCACTTTCTGAAA ATAAACATAAAACTGTTAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_013351 |
| Insert Size | 2600 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_013351.1, NP_037483.1 |
| RefSeq Size | 2589 bp |
| RefSeq ORF | 1608 bp |
| Locus ID | 30009 |
| UniProt ID | Q9UL17 |
| Domains | T-box |
| Protein Families | Druggable Genome, Transcription Factors |
| Gene Summary | This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
IL-36/IL-1F9, an Innate T-bet Target in Myeloid Cells
,Malte Bachmann, Patrick Scheiermann, Lorena Härdle, Josef Pfeilschifter, and Heiko Mühl,
J. Biol. Chem., Dec 2012; 287: 41684 - 41696.
[TBX21]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207902 | TBX21 (Myc-DDK-tagged)-Human T-box 21 (TBX21) |
CNY 5,976.00 |
|
| RC207902L1 | Lenti ORF clone of Human T-box 21 (TBX21), Myc-DDK-tagged |
CNY 8,376.00 |
|
| RC207902L2 | Lenti ORF clone of Human T-box 21 (TBX21), mGFP tagged |
CNY 8,376.00 |
|
| RC207902L3 | Lenti ORF clone of Human T-box 21 (TBX21), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC207902L4 | Lenti ORF clone of Human T-box 21 (TBX21), mGFP tagged |
CNY 8,376.00 |
|
| RG207902 | TBX21 (tGFP-tagged) - Human T-box 21 (TBX21) |
CNY 7,576.00 |
|
| SC115297 | TBX21 (untagged)-Human T-box 21 (TBX21) |
CNY 7,220.00 |
