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PACSIN1 (NM_020804) Human Untagged Clone
CAT＃: SC323836
PACSIN1 (untagged)-Human protein kinase C and casein kinase substrate in neurons 1 (PACSIN1), transcript variant 1
CNY 3,656.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | SDPI |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_020804.2
GCCTTCCTGAGTGAGCGGTGGAGGGAACCCTAGAGGACAGAGCCCCCAGCCCGGCAGCAG
GCCCCCTCTCCGCCCGCCACCACGGAGGAGAAGGAGGACAGCCAGCCCCTCCAGCCCTGG CCTGGCCCAGCGGGGGCAGTAAGCTCCTACTTGCCCCCAGCTTGGTGCCCACACGGGCCC AGTGCATGAGCAGCCGAGCCTGCTAACCGCAGCTCCGCACTTGTCCATCCCCCTGCGGCT ACACCATGTCCAGCTCCTACGATGAGGCCTCACTGGCGCCAGAGGAGACCACCGACAGCT TCTGGGAGGTGGGGAACTACAAGCGGACCGTGAAGCGCATCGATGACGGCCACCGTCTAT GCAACGACCTGATGAACTGCGTGCAGGAGCGCGCCAAGATCGAGAAGGCGTACGGGCAGC AGCTCACCGACTGGGCCAAGCGTTGGCGCCAGCTCATCGAGAAAGGCCCACAGTATGGCA GCCTGGAGCGGGCCTGGGGTGCCATAATGACAGAGGCAGACAAGGTGAGCGAGCTGCACC AGGAGGTGAAGAACAATCTGCTGAATGAGGACCTGGAGAAGGTGAAGAACTGGCAGAAGG ACGCCTATCACAAGCAGATCATGGGTGGCTTCAAGGAGACGAAGGAGGCTGAAGATGGCT TCCGCAAGGCCCAGAAGCCTTGGGCCAAGAAGATGAAGGAGCTGGAGGCAGCCAAGAAGG CCTACCATTTGGCTTGCAAAGAGGAAAAGCTGGCCATGACACGGGAGATGAACAGCAAGA CGGAGCAATCGGTCACACCTGAGCAGCAAAAGAAGCTGCAGGACAAAGTGGACAAGTGCA AGCAGGATGTGCAGAAGACACAGGAGAAGTATGAGAAAGTGCTGGAAGATGTGGGCAAGA CCACACCCCAGTACATGGAGAACATGGAGCAGGTGTTTGAGCAATGCCAGCAATTTGAGG AAAAGCGGCTGGTCTTCCTCAAGGAGGTGCTGCTGGACATCAAACGGCACCTCAACCTGG CTGAGAACAGCAGCTACATCCATGTGTACCGTGAGCTGGAGCAGGCCATCCGGGGGGCTG ATGCCCAGGAAGACCTCAGATGGTTCCGCAGCACCAGTGGCCCCGGCATGCCCATGAACT GGCCCCAGTTTGAGGAGTGGAACCCAGACCTTCCTCACACCACCACCAAGAAGGAGAAAC AGCCTAAGAAGGCAGAGGGAGTGGCGCTGACCAATGCCACTGGGGCGGTAGAGTCCACAT CCCAGGCTGGGGACCGCGGCAGTGTTAGCAGCTACGACAGAGGCCAGCCCTACGCCACCG AGTGGTCAGACGACGAGAGTGGGAACCCCTTTGGGGGCAGTGAGACCAACGGGGGCGCCA ACCCCTTTGAGGACGACTCCAAGGGAGTGCGCGTGCGGGCACTCTACGACTATGACGGCC AGGAGCAGGACGAGCTCAGCTTTAAGGCCGGAGACGAACTCACCAAGCTGGGCGAGGAGG ATGAGCAGGGCTGGTGCCGTGGGCGGCTGGACAGCGGGCAGCTGGGCCTCTACCCTGCCA ACTACGTGGAGGCTATCTAGAGGCCCCCTCCCTCCATACTCCCGTCACTCCTCCCCACTG CCGCCCCTCCCCTCCCACTCTCGTCTCCTTCCCCTCGCCATAGAGTTCCAGACATATTTT CCGATCAAGCTTTTATTTTTTTAAAAGTCAAAACAGAACAAAACAAAGTATGCAGAGACA GAGCATTTGCAGGGCCACCTGGAGGCTGGGGTGCTGGGGCTTGGGGTGGCCCCAGGGTAG GTAACAGTCTTAGGACTTAGCCCAACATCACAACATCTGCTCTTCGGGTTCCACCAAAGA GTCTCCTGAGCCCTGAGGGATGGATGTCTCCTGACCCTTCCACCCCGCCTCACTCCCTCC GTCCCACTCCACTCCAGGCTGCCGGCACCTGCCCCATTCCCTGGCCTGGTTTCCTAACCT CTTCTTCCTCCCCTGCCCCGCTTCCCTTCCTCCACCACCCTGCTCTCAAAGGCCTCCTCT CCAGACCCCTGGAAGGGAGGCTTCCCCATCTTTAGTTTTCCACTCTGCCCCGGGGAGCAC CCTTCTACTCCTAGCCACGTCCCTTGGGACCGGTGGGACTGGAGGAGGAACGGTCACCCT CCTCCCCCATGGAGGTTTCCAGGGGTCCCCCAGACATGAAAGAGGGGTGAGCTGGAGGAA GTCATGGTGTCACTGGGGTACAGGAGGGTGAATGAAGGGCATGCAGGCCCTCAGCCCGGG CTGTGCCAGCCCTCCCAGCCCCAGGCCCATCTGAGGGACCAAGACGCTGTTACGCAGGCC CTTCTTTCCAGCTATCAGCACTTTCAGCATCGGCTCTTCAGCAGATCCAAACCCCCTCAG CAACTTGCAGAGGACCTGTCCCCTCTCAAAAGTCCCCTGGCCTAGGGTGGGGACCCCCAA ACCTACGGCAAAGCCAGCAACAGTAGCAGCCTGCTCCCATTTGCTGGGGAGGAGATCATC TTGTTCCCCTGGCCCCCCACTCTCCCTCCATGTCCATCCAAAAACCATAAAATCACTGGG TTCCACATCAGCCTCCATGAGGCCAAGCCTTGTACCTGCAAGGCTCTTGGCCTAACCATT CCTCTGTCCTCTTCTCTGGCCTGCCTGGGGAGCCCGTGAAGGCCGCACGGGTGCCTCCAG CCTGAGACATCAGGGGAGAGCCTGCAGCTGAGTTCAGCAGAAAGGAGGAATCCTGGCCCT CAGGAAGAAGATAGTCACATGTTTTTCTTCCTTGTCCCCACAGCCCCCAGAACAACATTC TCCCTGCTGGCAGCCCTTCCATGTCTCCAAACCTGGGTCAGAGTGAAAGGACCTTTGGGG GTGGGTGGGAGCAAAGGGCCCACCTGCTGGTTGGTGAAAGCAGTGGTGCCGGAGTGCTAG GTACCGCACGAGAGGGTGCGGGGGCTTGGGAAGCAGACCAGGGTTGGACAAAACCCCATG AGGGCGGGGAGCTGGAAGAAAAGTCTCTTGGGGACCTCTGGGGCAAGGAGCTGAGAAGTC CTGCAGCACCAGGTGAGACTTGCTTACAGTGGATGCCACTTCTAGGCCTCTGGACCGCAG ATGCCCTCCTCCCTCCTGCACACCTGGCCTCCTGGGCCTCCAGGTAAAGAGAGAGAGCCA GCCCAGCCCTGTTTCCCCTCAGTCCTCCTTTGCTCCTGCTGCTTCTCCCAACAGCCCACT GTTAGGAGGTAGTAGACCCCAGCCTCAAGGCTCTGACCTTCTTCATGTGGGCACAGAGGG TCCTGACACTCTGGCAGGGCCTGAGCTGGGGCAGGCCTCCCTCAGGGCCAGGGGCGATGG CACCCCGGGGACAGGCAGACCTCCTTCCTGCCGTCAGCACCCCCTTCCTTATCACTGTCT GGTCTCCGAGCTTCGGCTGCAGCCTGAGGTGTGTCCTGGGCTCCTCAGAGCCTGAAGCAA GCTTTTGGAAGCCTGCAGTCCTCCCAGCTCCAGTGCAGAAGCCTCTCTCTCCAGCCTTTC CCCAGGCAGGAGTTGGGGTTGGGGGCCTCTGTCCCTCATCGCTTACCTTGGAAAGGTGGG AAGCTGGCAATCTGCACCTTGGGGCCTGGGCTCCCCCTCTCTGTGCCAGCGGCTTCCCAG CACCTGGGAGGGGCTGCAGCCCCAGCTGGACTCCAGCCTGTCCCTCTTAGCACTCTAGCT GCCCACTCCAGGGCAGGGACTCGAAACCCCCTCCGTCCTGAGCAGCCACCTCCAGGGCCC TGTTTGGGACCACTCTCTCAGTCCCCAGGTCCTCAGGGCCCCAGAGCGGGAGGGTCTCCT ACCTGGAAGTCCCCCTGAGCTCCAGGGCCCAGCCCTACCTGCCAGTGCTGGTGTCAGGGC ACTCAACACCGAGTGTGGGGGCCACGCCCCTTGCCATGCCCACGGCCTCCTCCTGTAGCC CCTGCCTGCACCCACGATGCTGCACGGGCCCGCCCTGGTGGGGCTCGGCGAGTAATGTGT TTTGTCCCCAGTTAACCACCATTCTGCGGCCTGGTTCTGCAAGGAACCAGGGCTGCCCCA CCGCCCGCCGTCTGCCGCCCTAGGCTTCCTGACTCCATTAGTTCCGACACTTGTGAAACT CCGAGAAGTGCTGTGGTCTCAGCAATGCACCTGTTTTGTACATGATTGTGTAATTTAAAG GTATATAAATACAAATATATATATATATCAGTTGTGATTGTATGACTGTGGATAAAATCC AGAACTGTGTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | ECoRI-NOT |
| ACCN | NM_020804 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_020804.2, NP_065855.1 |
| RefSeq Size | 4282 bp |
| RefSeq ORF | 1335 bp |
| Locus ID | 29993 |
| UniProt ID | Q9BY11 |
| Domains | FCH, SH3 |
| Protein Families | Druggable Genome |
| Gene Summary | Plays a role in the reorganization of the microtubule cytoskeleton via its interaction with MAPT; this decreases microtubule stability and inhibits MAPT-induced microtubule polymerization. Plays a role in cellular transport processes by recruiting DNM1, DNM2 and DNM3 to membranes. Plays a role in the reorganization of the actin cytoskeleton and in neuron morphogenesis via its interaction with COBL and WASL, and by recruiting COBL to the cell cortex. Plays a role in the regulation of neurite formation, neurite branching and the regulation of neurite length. Required for normal synaptic vesicle endocytosis; this process retrieves previously released neurotransmitters to accommodate multiple cycles of neurotransmission. Required for normal excitatory and inhibitory synaptic transmission (By similarity). Binds to membranes via its F-BAR domain and mediates membrane tubulation.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206626 | PACSIN1 (Myc-DDK-tagged)-Human protein kinase C and casein kinase substrate in neurons 1 (PACSIN1), transcript variant 1 |
CNY 3,656.00 |
|
| RC206626L3 | Lenti ORF clone of Human protein kinase C and casein kinase substrate in neurons 1 (PACSIN1), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC206626L4 | Lenti ORF clone of Human protein kinase C and casein kinase substrate in neurons 1 (PACSIN1), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG206626 | PACSIN1 (tGFP-tagged) - Human protein kinase C and casein kinase substrate in neurons 1 (PACSIN1), transcript variant 1 |
CNY 4,370.00 |
|
| SC100472 | PACSIN1 (untagged)-Human protein kinase C and casein kinase substrate in neurons 1 (PACSIN1), transcript variant 1 |
CNY 3,656.00 |
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