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ALIX (PDCD6IP) (NM_013374) Human Untagged Clone
CAT＃: SC323909
PDCD6IP (untagged)-Human programmed cell death 6 interacting protein (PDCD6IP), transcript variant 1
CNY 6,368.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AIP1; ALIX; DRIP4; HP95 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_013374.3
CTGTCAGCCAGTCAGTCCGCCAGTCCGCCAGCCCAGTACCTCTCTCTCCTCGGCCCTCGT
AAGCTGTCCGCGGTCTGTTTGGCCCGAACGGCGGCGGAGGCGCTGATCATGGCGACATTC ATCTCGGTGCAGCTGAAAAAGACCTCAGAGGTGGACCTGGCCAAGCCGCTGGTGAAGTTC ATCCAGCAGACTTACCCAAGCGGCGGGGAAGAGCAGGCCCAGTACTGCCGCGCGGCGGAG GAGCTCAGCAAGCTGCGCCGCGCCGCAGTCGGTCGTCCGCTGGACAAGCACGAGGGCGCG CTCGAGACGCTCCTGAGATATTATGATCAGATTTGTTCTATTGAACCCAAATTCCCATTT TCTGAAAATCAGATCTGCTTGACATTTACCTGGAAGGATGCTTTCGATAAAGGTTCACTT TTTGGAGGCTCTGTAAAACTGGCTCTTGCAAGCTTAGGATATGAAAAGAGCTGTGTGTTG TTCAATTGTGCAGCCTTAGCTAGCCAAATTGCAGCAGAACAGAACCTGGATAATGATGAA GGATTGAAAATCGCTGCTAAACATTACCAGTTTGCTAGTGGTGCCTTTTTACATATTAAA GAGACGGTTTTATCTGCCTTAAGTCGAGAGCCGACCGTGGACATATCTCCAGATACTGTT GGGACCCTCAGTCTTATTATGCTGGCACAGGCTCAAGAAGTATTTTTTTTAAAAGCCACA AGAGATAAAATGAAAGATGCCATCATAGCTAAATTGGCTAATCAGGCTGCAGATTATTTT GGTGATGCTTTCAAACAGTGTCAATACAAAGATACTCTCCCCAAGGAGGTGTTCCCTGTC TTGGCTGCAAAGCACTGTATCATGCAGGCCAATGCTGAGTACCATCAGTCTATCCTGGCA AAACAGCAGAAGAAATTTGGAGAAGAAATTGCAAGGTTACAGCATGCAGCAGAACTGATT AAAACAGTGGCATCTCGCTATGATGAATATGTTAATGTGAAGGATTTTTCTGACAAAATC AATCGTGCCCTTGCTGCAGCAAAGAAGGATAATGACTTCATTTATCATGATCGAGTTCCA GACCTTAAAGATCTAGATCCTATTGGCAAAGCCACACTTGTGAAATCTACCCCGGTCAAT GTACCCATCAGTCAGAAATTTACTGATCTGTTTGAGAAGATGGTTCCCGTGTCAGTACAG CAGTCTTTGGCTGCCTATAATCAGAGGAAAGCCGATTTGGTTAACAGATCAATTGCTCAG ATGAGAGAAGCCACCACTTTGGCAAATGGGGTGCTAGCTTCCCTTAATCTTCCAGCAGCA ATTGAAGATGTGTCTGGAGACACTGTACCTCAGTCTATATTGACTAAATCCAGATCTGTG ATTGAACAGGGAGGCATCCAGACTGTTGATCAGTTGATTAAAGAACTGCCTGAATTACTG CAACGAAATAGAGAAATCCTAGATGAGTCATTAAGGTTGTTGGATGAAGAAGAAGCAACC GATAATGATTTAAGAGCAAAATTTAAGGAACGTTGGCAAAGGACACCATCCAATGAACTG TATAAGCCTTTAAGAGCAGAGGGAACCAACTTCAGAACAGTTTTAGATAAAGCTGTGCAG GCAGATGGACAAGTGAAAGAATGTTACCAGTCTCATCGTGACACCATCGTGCTTTTGTGT AAGCCAGAGCCTGAGCTGAATGCTGCCATCCCTTCTGCTAATCCAGCAAAGACCATGCAG GGCAGTGAGGTTGTAAATGTCTTAAAATCCTTATTGTCAAATCTTGATGAAGTAAAGAAG GAAAGAGAGGGTCTGGAGAATGACTTGAAATCTGTGAATTTTGACATGACAAGCAAGTTT TTGACAGCCCTGGCTCAAGATGGTGTGATAAATGAAGAAGCTCTTTCTGTTACTGAACTA GATCGAGTCTATGGAGGTCTTACAACTAAAGTCCAAGAATCTCTAAAGAAACAGGAGGGA CTTCTTAAAAATATTCAGGTCTCACATCAGGAATTTTCAAAAATGAAACAATCTAATAAT GAAGCTAACTTAAGAGAAGAAGTTTTGAAGAATTTAGCTACTGCATATGACAACTTTGTT GAACTTGTAGCTAATTTGAAGGAAGGCACAAAGTTTTACAATGAGTTGACTGAAATCCTG GTCAGGTTCCAGAACAAATGCAGTGATATAGTTTTTGCACGGAAGACAGAAAGAGATGAA CTCTTAAAGGACTTGCAACAAAGCATTGCCAGAGAACCTAGTGCTCCTTCAATTCCTACA CCTGCGTATCAGTCCTCACCAGCAGGAGGACATGCACCAACTCCTCCAACTCCAGCGCCA AGAACCATGCCGCCTACTAAGCCCCAGCCCCCAGCCAGGCCTCCACCACCTGTGCTTCCA GCAAATCGAGCTCCTTCTGCTACTGCTCCATCTCCAGTGGGGGCTGGGACTGCTGCGCCA GCTCCATCACAAACGCCTGGCTCAGCTCCTCCTCCACAGGCGCAGGGACCACCCTATCCC ACCTATCCAGGATATCCTGGGTATTGCCAAATGCCCATGCCCATGGGCTATAATCCTTAT GCGTATGGCCAGTATAATATGCCATATCCACCAGTGTATCACCAGAGTCCTGGACAGGCT CCATACCCGGGACCCCAGCAGCCTTCATACCCCTTCCCTCAGCCCCCACAGCAGTCTTAC TATCCACAGCAGTAATATGTCTGCTCAGCAGCTCAGCTGATTCAGATCAGAGGGAAAGAA ATACCAACCCTGCAATAAGTGTACTAAACTCTACGCTCTGGTTAATGTAATGTACTCTCC TGGACTGAATGCAGTGTATAATTTCTGTCTACAGCTAGAAGCTGTGCCCCAGTTCCACAT TTGATTACACATGTGAGATTTGCTGCTGTTGCAGTATAAACACTAGGTATAATAGGATTT GAAATTGCATTACAGTTCATAAAAATTGAAAATGAGAAATTAAACCTGCAAGTGAAACAT TTGAAACGATTATACTTTCTACATAAGACATGGTTGGGACATCAGATACTTACAAAGATG GTTTAAGTATGGATACTAGAGAAAATTAAGTTTTCTTTCTCTTTGGTTTATTGATTTGGT TTAATTTCCATTATGCTATTTTGCATAATCAAGGCACTGTAAATCTTATAATTTTAAAAT AAATTACTTAAGAACAGTTGTCATTGTTATGTTTTGTTATTGATTCTCATTACTGTCTAA TTTTTTTTCTGGTATTAGTCTCATTTTGTATGTATATAAGTTAAACAGATACTGTTTTTA AGTGCATGAATAGTACAAGTTATTATCAAGGATGTTTTACAGGGAAATCAAAAGAATATT ATCATACTTTATCTTTCGTATGCTGATTAGTAAACGATTTTTGACATTTATTTTAGAAAG TCCTATAATGTGGAAGAAACAAACAGTTGCTACCAAAGATGATGAAAATAAACATACAAA TAAATGTGTATATTTAATGTTTTATTGTTAGCTTCTCCAGAAAATTGATGCAAATTCTGG TAATAATTCTTGCATTTTTTCCCCATAACCTGGTTAAAATAAATACGCCATTGGCAATAA AAAAAAAAAAAAA |
| Restriction Sites | ECoRI-NOT |
| ACCN | NM_013374 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_013374.3, NP_037506.2 |
| RefSeq Size | 6448 bp |
| RefSeq ORF | 2607 bp |
| Locus ID | 10015 |
| UniProt ID | Q8WUM4 |
| Domains | BRO1 |
| Protein Families | Druggable Genome |
| Protein Pathways | Endocytosis |
| Gene Summary | This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. [provided by RefSeq, Jan 2012] Transcript Variant: This variant (1) uses an alternate in-frame splice site in the central coding region, compared to variant 2, resulting in an isoform (1) that is shorter than isoform 2. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203735 | PDCD6IP (Myc-DDK-tagged)-Human programmed cell death 6 interacting protein (PDCD6IP), transcript variant 1 |
CNY 6,360.00 |
|
| RC203735L1 | Lenti ORF clone of Human programmed cell death 6 interacting protein (PDCD6IP), transcript variant 1, Myc-DDK-tagged |
CNY 8,760.00 |
|
| RC203735L2 | Lenti ORF clone of Human programmed cell death 6 interacting protein (PDCD6IP), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC203735L3 | Lenti ORF clone of Human programmed cell death 6 interacting protein (PDCD6IP), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC203735L4 | Lenti ORF clone of Human programmed cell death 6 interacting protein (PDCD6IP), transcript variant 1, mGFP tagged |
CNY 8,760.00 |
|
| RG203735 | PDCD6IP (tGFP-tagged) - Human programmed cell death 6 interacting protein (PDCD6IP), transcript variant 1 |
CNY 7,960.00 |
|
| SC115270 | PDCD6IP (untagged)-Human programmed cell death 6 interacting protein (PDCD6IP), transcript variant 1 |
CNY 6,368.00 |
