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DCK (NM_000788) Human Untagged Clone
CAT＃: SC324233
DCK (untagged)-Human deoxycytidine kinase (DCK)
CNY 3,990.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_000788.1
CGCAGGCCCGCCAGTGTCCTCAGCTGCCTCCGCGCGCCAAAGTCAAACCCCGACACCCGC
CGGCGGGCCGGTGAGCTCACTAGCTGACCCGGCAGGTCAGGATCTGGCTTAGCGGCGCCG CGAGCTCCAGTGCGCGCACCCGTGGCCGCCTCCCAGCCCTCTTTGCCGGACGAGCTCTGG GCCGCCACAAGACTAAGGAATGGCCACCCCGCCCAAGAGAAGCTGCCCGTCTTTCTCAGC CAGCTCTGAGGGGACCCGCATCAAGAAAATCTCCATCGAAGGGAACATCGCTGCAGGGAA GTCAACATTTGTGAATATCCTTAAACAATTGTGTGAAGATTGGGAAGTGGTTCCTGAACC TGTTGCCAGATGGTGCAATGTTCAAAGTACTCAAGATGAATTTGAGGAACTTACAATGTC TCAGAAAAATGGTGGGAATGTTCTTCAGATGATGTATGAGAAACCTGAACGATGGTCTTT TACCTTCCAAACATATGCTTGTCTCAGTCGAATAAGAGCTCAGCTTGCCTCTCTGAATGG CAAGCTCAAAGATGCAGAGAAACCTGTATTATTTTTTGAACGATCTGTGTATAGTGACAG GTATATTTTTGCATCTAATTTGTATGAATCTGAATGCATGAATGAGACAGAGTGGACAAT TTATCAAGACTGGCATGACTGGATGAATAACCAATTTGGCCAAAGCCTTGAATTGGATGG AATCATTTATCTTCAAGCCACTCCAGAGACATGCTTACATAGAATATATTTACGGGGAAG AAATGAAGAGCAAGGCATTCCTCTTGAATATTTAGAGAAGCTTCATTATAAACATGAAAG CTGGCTCCTGCATAGGACACTGAAAACCAACTTCGATTATCTTCAAGAGGTGCCTATCTT AACACTGGATGTTAATGAAGACTTTAAAGACAAATATGAAAGTCTGGTTGAAAAGGTCAA AGAGTTTTTGAGTACTTTGTGATCTTGCTGAAGACTACAGGCAGCCAAATGGTTCCAGAT ACTTCAGCTTTGTGTATCTTCGTAACTTCATATTAATATAAGTTTCTTTAGAAAACCCAA GTTTTTAATCGTTTTTGTTTTAAGGAAAAAAGATTTTTAAAATGAATCTTATGCAAAACT TTTTGATCAGTTTCTTTTCTTTTGTTTTTTTTTTAAAAAAGACATTTAAAGACAAAGACA TTATTTCTCATAGCAGGAAATGTAGAGGTAGATGGTTCCAGTATCAGCATAGTGACTAAA CTACATTATAAAAGATCCAGCTTCCTTCTGTCATTCCCCTCTTTTGTCTTCCTCAGCAGG TTGGCTTTTTTCCCTGGTGCCTCTCACTTCGTTGGTGACCAGTTTCTTAAACTGAAAGCT TTAATGTTACATAGTAAATGGTAGTGTGTCCTGTGTAAATTAGTGTACCTATTAAAAGTT GCAAAGTGGAATTAAAGGAATCCCTAGAATAAGGATTCTGAAGTTTTATTTTAAATTATT ATCTTCTTAACAGTTTAGTCCCACCTCTTACTTCCTGCCTCAGTCTGCTTTCTCTACTGT CTGGATTAATTAGGCAGCCTGCTATAAAGTTAAAGTCACACATTTCTATTTTGCAAACAC TGTGATTACTCTTTGCTTTGTAGTTTGCTTTGCTTTGTAGGGTTCTGCTTTTAAGTTTTT CTCTTTTTCAGACAAATTACTGATAAAAATGATATTGCTCTATATGTAATATATCCTGAA AGCATTATTTTTTGTTGAATAGGAAATAAAATTAATGAAGACAGAGGCTAGAAAGCATCC ATTAATTAATGAGACACACTTAACTACTTATCTCTAAACCATCTATGTGAATATTTGTAA AAATAATGAATGGACTCATCTTAGTTCTGTATATAAATATATTTTCTTTCTAGTTTGTTT AGTTAAGGTGTGCAGTGTTTTTCCTGTGTATTAAACCTTTCCATTTTACGTTTTAGAAAA TTTTATGTATTTTAAAATAAGGGGAAGAGTCATTTTCACTTTTAAACTACTATTTTTCTT TCCAAGTCATTTTTGTTTTTGGTTTCTTATTCAAAGATGATAATTTAGTGGATTAACCAG TCCAGACGCACTGATCTTTGCAAAGGAGACTTAATTTCAAATCTGTAATTACCATACATA AACTGTCTCATTATAAGTATGCATTTTTTTAGTTTGTTTTTGTTTGGTATAAATTAATTT GTTAATTAAATATTTCTTAAGTATAAACCTTATGAACTACAGTGGAGCTACACTCATTGA AATGTAATTTCAGTTCTAAAAAGATGTAATAATCATTTTAGAATTAAAATTTATTCTACT TTTAAATAAATTATGAATATTAAAGGTGAAAATTGTATAAATTACTTTGATTCCATTTTA AGTGGAGACATATTTCAGTGATTTTTAGTAACCTTTAAAAATGTATAATGACTTTTAAAA TTTGTAGAATTGAAAAGACGCTAATAAAAATTTATTATTTATTTGTCATGACTCAAAAAA AAAAAAAAA |
| Restriction Sites | ECoRI-NOT |
| ACCN | NM_000788 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000788.1, NP_000779.1 |
| RefSeq Size | 2460 bp |
| RefSeq ORF | 783 bp |
| Locus ID | 1633 |
| UniProt ID | P27707 |
| Domains | dNK |
| Protein Families | Druggable Genome |
| Protein Pathways | Purine metabolism, Pyrimidine metabolism |
| Gene Summary | Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq, Jul 2008] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210767 | DCK (Myc-DDK-tagged)-Human deoxycytidine kinase (DCK) |
CNY 3,600.00 |
|
| RC210767L1 | Lenti ORF clone of Human deoxycytidine kinase (DCK), Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC210767L2 | Lenti ORF clone of Human deoxycytidine kinase (DCK), mGFP tagged |
CNY 5,890.00 |
|
| RC210767L3 | Lenti ORF clone of Human deoxycytidine kinase (DCK), Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC210767L4 | Lenti ORF clone of Human deoxycytidine kinase (DCK), mGFP tagged |
CNY 6,000.00 |
|
| RG210767 | DCK (tGFP-tagged) - Human deoxycytidine kinase (DCK) |
CNY 5,200.00 |
|
| SC119688 | DCK (untagged)-Human deoxycytidine kinase (DCK) |
CNY 3,600.00 |
