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PIAS3 (NM_006099) Human Untagged Clone
CAT＃: SC324304
PIAS3 (untagged)-Human protein inhibitor of activated STAT, 3 (PIAS3)
CNY 4,680.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ZMIZ5 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_006099.3
CTGGGCCTGAGCTCCGGCTCCGGCTGGGGCGCCTGCGATGTCTCAAGATGGCGGAGCTGG
GCGAATTAAAGCACATGGTGATGAGTTTCCGGGTGTCTGAGCTCCAGGTGCTTCTTGGCT TTGCTGGCCGGAACAAGAGTGGACGGAAGCACGAGCTCCTGGCCAAGGCTCTGCACCTCC TGAAGTCCAGCTGTGCCCCTAGTGTCCAGATGAAGATCAAAGAGCTTTACCGACGACGCT TTCCCCGGAAGACCCTGGGGCCCTCTGATCTCTCCCTTCTCTCTTTGCCCCCTGGCACCT CTCCTGTAGGCTCCCCTGGTCCTCTAGCTCCCATTCCCCCAACGCTGTTGGCCCCTGGCA CCCTGCTGGGCCCCAAGCGTGAGGTGGACATGCACCCCCCTCTGCCCCAGCCTGTGCACC CTGATGTCACCATGAAACCATTGCCCTTCTATGAAGTCTATGGGGAGCTCATCCGGCCCA CCACCCTTGCATCCACTTCTAGCCAGCGGTTTGAGGAAGCGCACTTTACCTTTGCCCTCA CACCCCAGCAAGTGCAGCAGATTCTTACATCCAGAGAGGTTCTGCCAGGAGCCAAATGTG ATTATACCATACAGGTGCAGCTAAGGTTCTGTCTCTGTGAGACCAGCTGCCCCCAGGAAG ATTATTTTCCCCCCAACCTCTTTGTCAAGGTCAATGGGAAACTGTGCCCCCTGCCGGGTT ACCTTCCCCCAACCAAGAATGGGGCCGAGCCCAAGAGGCCCAGCCGCCCCATCAACATCA CACCCCTGGCTCGACTCTCAGCCACTGTTCCCAACACCATTGTGGTCAATTGGTCATCTG AGTTCGGACGGAATTACTCCTTGTCTGTGTACCTGGTGAGGCAGTTGACTGCAGGAACCC TTCTACAAAAACTCAGAGCAAAGGGTATCCGGAACCCAGACCACTCGCGGGCACTGATCA AGGAGAAATTGACTGCTGACCCTGACAGTGAGGTGGCCACTACAAGTCTCCGGGTGTCAC TCATGTGCCCGCTAGGGAAGATGCGCCTGACTGTCCCTTGTCGTGCCCTCACCTGCGCCC ACCTGCAGAGCTTCGATGCTGCCCTTTATCTACAGATGAATGAGAAGAAGCCTACATGGA CATGTCCTGTGTGTGACAAGAAGGCTCCCTATGAATCTCTTATCATTGATGGTTTATTTA TGGAGATTCTTAGTTCCTGTTCAGATTGTGATGAGATCCAATTCATGGAAGATGGATCCT GGTGCCCAATGAAACCCAAGAAGGAGGCATCTGAGGTTTGCCCCCCGCCAGGGTATGGGC TGGATGGCCTCCAGTACAGCCCAGTCCAGGGGGGAGATCCATCAGAGAATAAGAAGAAGG TCGAAGTTATTGACTTGACAATAGAAAGCTCATCAGATGAGGAGGATCTGCCCCCTACCA AGAAGCACTGTTCTGTCACCTCAGCTGCCATCCCGGCCCTACCTGGAAGCAAAGGAGTCC TGACATCTGGCCACCAGCCATCCTCGGTGCTAAGGAGCCCTGCTATGGGCACGTTGGGTG GGGATTTCCTGTCCAGTCTCCCACTACATGAGTACCCACCTGCCTTCCCACTGGGAGCCG ACATCCAAGGTTTAGATTTATTTTCATTTCTTCAGACAGAGAGTCAGCACTATGGCCCCT CTGTCATCACCTCACTAGATGAACAGGATGCCCTTGGCCACTTCTTCCAGTACCGAGGGA CCCCTTCTCACTTTCTGGGCCCACTGGCCCCCACGCTGGGGAGCTCCCACTGCAGCGCCA CTCCGGCGCCCCCTCCTGGCCGTGTCAGCAGCATTGTGGCCCCTGGGGGGGCCTTGAGGG AGGGGCATGGAGGACCCCTGCCCTCAGGTCCCTCTTTGACTGGCTGTCGGTCAGACATCA TTTCCCTGGACTGAGTTCCCTGGATTATGGAAACTTCGCTGTCCCCCAACACTGAGCAAG TATGCTGTGGAGTCCCAACCCCAGCTACTCTGATCCCTCTGGGGGCTCTGGCCAAGGGCC AGACAGACCTTCACAGATGCCTACTTTTGGCCTCATCTCTGCCTGACAAGGCCAGCACCC AAAGGGTTAATATTTAACCTCTTTTTAAGGACACTGGGGTCTGTTTCTGGAAATGTTCTT TAGATGGTGGCACATTCCTTTGGGTATGTTAACCTAGGCAGTGGGAGGCAAATGGGATGG TATGTGAGCTAGGAGAAGGGCTGAACCCTCAGCCTTGACTATGTCTAGAGCCTCTTGGGG AAGGGGCACCTCTCTTGAACCCCAAATGCTCTCTCTTCTTATTACCCAAACCCATGGCTC TATTTCTTCTTCACATCCATTGTCTCTTCATGTCTATTCCATTCCCTTCGGCCAAACAGA CAGGTGGAAAAACTGAGACAGGCAGTTTCAGAGATGGACAGAGAACTTTATTTTGGATTG TGGATGTGGACTTTTTTGTACATAAATAAGAAAAACCAAAATACTCCAAAGATGACTTCC CCTGCCTCCTACTCCAGTATGACAGAGGAGGATGTAAGGCCTTAGCCATGATCTGCAGGG GTCTGGGAGTCAGGCCCGGCCTATTGCTTGGGTCTCTCTCTATTTATATATCTAAGTTCA CAGTGTTTCTTATTCCCCCCTAAGCTTCTAGAGGCTCATGGCCCTGTAGTTAGGCCTGGC TCATTCTGCACCTTTCCAGGGAGGTGGAAGGACCCTGTGCCCTCCTTCCCAATCTTCTTT TTCAGGCTCGCCAAGGCCTAGGACCTATGTTGTAATTTTACTTTTTATTTCTAAAGTTGT AGTGAAGCTCTCACCCATAATAAAGGTTGTGAATGTTCAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_006099 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_006099.3, NP_006090.2 |
| RefSeq Size | 2902 bp |
| RefSeq ORF | 1887 bp |
| Locus ID | 10401 |
| UniProt ID | Q9Y6X2 |
| Domains | SAP, zf-MIZ |
| Protein Families | Transcription Factors |
| Protein Pathways | Jak-STAT signaling pathway, Pathways in cancer, Small cell lung cancer, Ubiquitin mediated proteolysis |
| Gene Summary | This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Traditional Chinese medicine, Fuzheng Kang‑Ai decoction, inhibits metastasis of lung cancer cells through the STAT3/MMP9 pathway
,Li, L;Wang, S;Yang, X;Long, S;Xiao, S;Wu, W;Hann, SS;,
Mol Med Rep
,PubMed ID 28677797
[PIAS3]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207034 | PIAS3 (Myc-DDK-tagged)-Human protein inhibitor of activated STAT, 3 (PIAS3) |
CNY 4,680.00 |
|
| RC207034L1 | Lenti ORF clone of Human protein inhibitor of activated STAT, 3 (PIAS3), Myc-DDK-tagged |
CNY 7,080.00 |
|
| RC207034L2 | Lenti ORF clone of Human protein inhibitor of activated STAT, 3 (PIAS3), mGFP tagged |
CNY 5,890.00 |
|
| RC207034L3 | Lenti ORF clone of Human protein inhibitor of activated STAT, 3 (PIAS3), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC207034L4 | Lenti ORF clone of Human protein inhibitor of activated STAT, 3 (PIAS3), mGFP tagged |
CNY 5,890.00 |
|
| RG207034 | PIAS3 (tGFP-tagged) - Human protein inhibitor of activated STAT, 3 (PIAS3) |
CNY 6,280.00 |
|
| SC116323 | PIAS3 (untagged)-Human protein inhibitor of activated STAT, 3 (PIAS3) |
CNY 4,616.00 |
