United States
Germany
Japan
United Kingdom
China
OTUD5 (NM_001136158) Human Untagged Clone
CAT＃: SC326074
OTUD5 (untagged)-Human OTU domain containing 5 (OTUD5), transcript variant 3
CNY 9,120.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DUBA; MCAND |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC326074 representing NM_001136158.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTA CCGAGGAGATCTGCCGCCGCGATCGCCGGCGCGCCC ATGACTATACTCCCCAAAAAGAAGCCGCCGCCTCCCGACGCCGACCCCGCCAACGAGCCGCCGCCGCCC GGGCCGATGCCCCCGGCGCCGCGGCGCGGCGGAGGTGTGGGCGTGGGCGGCGGCGGCACGGGCGTGGGC GGCGGCGATCGCGACCGTGACTCCGGCGTCGTGGGGGCCCGTCCGCGAGCTTCGCCACCGCCTCAAGGC CCGCTACCAGGACCGCCGGGCGCTCTTCATCGCTGGGCGCTGGCCGTGCCGCCTGGTGCAGTGGCGGGT CCCCGGCCACAACAGGCTTCTCCACCTCCTTGCGGGGGCCCAGGTGGTCCCGGCGGCGGTCCCGGCGAC GCGCTGGGCGCAGCGGCGGCGGGTGTGGGTGCCGCGGGCGTGGTGGTGGGTGTGGGTGGTGCCGTAGGC GTGGGCGGCTGCTGCTCCGGGCCTGGGCACAGCAAGCGGCGACGTCAAGCTCCCGGGGTTGGCGCGGTT GGCGGGGGCAGTCCCGAGCGTGAGGAGGTCGGCGCAGGCTACAACAGTGAGGACGAGTATGAGGCGGCT GCAGCACGCATCGAGGCTATGGACCCTGCCACTGTCGAGCAGCAGGAGCATTGGTTTGAAAAGGCCCTA CGAGACAAGAAGGGCTTCATCATCAAGCAGATGAAGGAGGATGGCGCCTGTCTCTTCCGGGCTGTAGCT GACCAGGTGTATGGAGACCAGGACATGCATGAGGTTGTGCGAAAGCATTGCATGGACTATCTGATGAAG AATGCCGACTACTTCTCCAACTATGTCACAGAGGACTTTACCACCTACATTAACAGGAAGCGGAAAAAC AATTGCCATGGCAACCACATTGAGATGCAGGCCATGGCAGAGATGTACAACCGTCCTGTGGAGGTGTAC CAGTACAGCACAGAACCCATCAACACATTCCATGGGATACATCAAAACGAGGACGAACCCATTCGTGTT AGCTACCATCGGAATATCCACTATAATTCAGTGGTGAATCCTAACAAGGCCACCATTGGTGTGGGGCTG GGCCTGCCATCATTCAAACCAGGGTTTGCAGAGCAGTCTCTGATGAAGAATGCCATAAAAACATCGGAG GAGTCATGGATTGAACAGCAGATGCTAGAAGACAAGAAACGGGCCACAGACTGGGAGGCCACAAATGAA GCCATCGAGGAGCAGGTGGCTCGGGAATCCTACCTGCAGTGGTTGCGGGATCAGGAGAAACAGGCTCGC CAGGTCCGAGGCCCCAGCCAGCCCCGGAAAGCCAGCGCCACATGCAGTTCGGCCACAGCAGCAGCCTCC AGTGGCCTGGAGGAGTGGACTAGCCGGTCCCCGCGGCAGCGGAGTTCAGCCTCGTCACCTGAGCACCCT GAGCTGCATGCTGAATTGGGCATGAAGCCCCCTTCCCCAGGCACTGTTTTAGCTCTTGCCAAACCTCCT TCGCCCTGTGCGCCAGGTACAAGCAGTCAGTTCTCGGCAGGGGCCGACCGGGCAACTTCCCCCCTTGTG TCCCTCTACCCTGCTTTGGAGTGCCGGGCCCTCATTCAGCAGATGTCCCCCTCTGCCTTTGGTCTGAAT GACTGGGATGATGATGAGATCCTAGCTTCGGTGCTGGCAGTGTCCCAACAGGAATACCTAGACAGTATG AAGAAAAACAAAGTGCACAGAGACCCGCCCCCAGACAAGAGTTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | AscI-MluI |
| ACCN | NM_001136158 |
| Insert Size | 1701 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001136158.1 |
| RefSeq Size | 2700 bp |
| RefSeq ORF | 1701 bp |
| Locus ID | 55593 |
| UniProt ID | Q96G74 |
| Protein Families | Protease |
| Protein Pathways | RIG-I-like receptor signaling pathway |
| MW | 60.2 kDa |
| Gene Summary | This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2008] Transcript Variant: This variant (3) differs in the 3' UTR and lacks an in-frame portion of an internal coding exon, compared to variant 1, resulting in a shorter protein compared to isoform a. Variants 2 and 3 encode the same isoform (b). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC227589 | OTUD5 (Myc-DDK-tagged)-Human OTU domain containing 5 (OTUD5), transcript variant 3 |
CNY 4,216.00 |
|
| RC227589L3 | Lenti ORF clone of Human OTU domain containing 5 (OTUD5), transcript variant 3, Myc-DDK-tagged |
CNY 6,460.00 |
|
| RC227589L4 | Lenti ORF clone of Human OTU domain containing 5 (OTUD5), transcript variant 3, mGFP tagged |
CNY 6,460.00 |
|
| RG227589 | OTUD5 (tGFP-tagged) - Human OTU domain containing 5 (OTUD5), transcript variant 3 |
CNY 5,040.00 |
