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Girdin (CCDC88A) (NM_001135597) Human Untagged Clone
CAT＃: SC326406
CCDC88A (untagged)-Human coiled-coil domain containing 88A (CCDC88A), transcript variant 1
CNY 36,010.00
货期*
9周
规格
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | APE; GIRDIN; GIV; GRDN; HkRP1; KIAA1212; PEHO; PEHOL |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_001135597, the custom clone sequence may differ by one or more nucleotides
ATGGAGAACGAAATTTTTACTCCCCTTCTGGAGCAGTTCATGACCAGCCCTTTGGTCACT TGGGTTAAAACGTTTGGACCTCTGGCCGCAGGAAATGGGACCAACCTTGATGAATATGTG GCTTTGGTGGATGGGGTATTCTTGAACCAGGTCATGCTCCAAATTAATCCTAAATTGGAG AGTCAGAGAGTAAATAAAAAAGTCAATAATGATGCCTCACTTAGAATGCACAATCTATCC ATTTTGGTGAGACAGATAAAATTTTATTACCAGGAGACTTTGCAGCAATTGATCATGATG TCGTTGCCAAATGTCTTAATCATTGGCAAAAATCCCTTTTCTGAACAAGGCACAGAAGAA GTTAAAAAACTGCTTTTACTTTTATTGGGTTGTGCAGTTCAGTGTCAGAAAAAAGAGGAA TTTATTGAAAGAATTCAAGGTTTAGATTTTGATACAAAAGCAGCGGTTGCCGCACATATT CAAGAGGTAACTCATAATCAGGAAAATGTGTTTGACCTGCAATGGATGGAAGTGACTGAT ATGTCGCAGGAGGACATAGAACCACTCTTGAAAAATATGGCATTGCATCTAAAAAGACTT ATAGATGAGAGAGATGAACATTCAGAGACTATCATAGAACTCTCTGAAGAGCGGGATGGT CTCCATTTTCTACCCCATGCCTCTTCATCTGCACAGTCACCCTGTGGTTCTCCAGGCATG AAGCGAACAGAAAGTCGACAACATCTGTCGGTGGAACTGGCAGATGCTAAAGCCAAGATA AGAAGGCTTAGGCAGGAATTGGAGGAAAAGACTGAGCAGTTGTTGGATTGTAAACAAGAA CTTGAGCAAATGGAAATAGAACTCAAAAGGCTGCAACAAGAGAACATGAATTTGCTTTCG GATGCTCGCTCTGCCAGAATGTACCGAGATGAATTAGATGCACTTCGAGAGAAAGCAGTC AGAGTCGATAAGCTTGAAAGTGAAGTCAGCAGATATAAAGAGAGACTACATGATATTGAA TTTTATAAGGCAAGAGTTGAGGAATTAAAAGAAGACAATCAAGTTTTATTAGAAACAAAA ACCATGTTGGAAGACCAACTAGAGGGAACTCGTGCTCGTTCTGATAAATTACATGAATTA GAAAAAGAGAACTTACAACTGAAAGCTAAACTTCATGATATGGAAATGGAACGAGATATG GATAGAAAAAAGATTGAAGAATTAATGGAAGAAAATATGACTTTGGAAATGGCACAGAAA CAAAGTATGGATGAATCATTACATCTTGGCTGGGAACTGGAACAGATATCCAGAACTAGT GAACTTTCCGAAGCACCCCAGAAATCCCTGGGCCATGAGGTGAATGAGTTGACATCAAGT AGATTATTGAAGCTAGAGATGGAAAATCAAAGTTTGACAAAAACCGTAGAAGAGCTTCGG ACTACTGTGGATTCTGTAGAAGGCAATGCTTCCAAAATCCTGAAAATGGAAAAAGAAAAT CAAAGGCTCAGTAAAAAGGTTGAGATTCTTGAAAATGAGATTGTTCAAGAAAAGCAAAGT CTTCAGAATTGTCAGAATTTAAGCAAGGATCTAATGAAGGAGAAAGCTCAGCTTGAAAAA ACAATAGAAACACTGAGAGAAAATTCAGAGAGACAGATTAAGATACTGGAACAGGAAAAT GAACATCTGAATCAAACAGTGTCTTCCTTAAGGCAGCGGTCCCAGATAAGTGCAGAAGCA AGAGTGAAAGACATTGAAAAAGAAAACAAAATTCTTCATGAATCTATCAAAGAAACAAGT AGCAAGCTAAGCAAGATTGAATTTGAAAAAAGACAAATTAAAAAAGAATTGGAACATTAT AAAGAAAAAGGAGAACGAGCTGAAGAACTTGAAAATGAATTGCATCATCTTGAAAAAGAA AATGAATTATTACAGAAAAAAATAACTAATTTAAAAATTACTTGTGAAAAAATTGAGGCC TTAGAACAAGAAAATTCAGAGCTAGAAAGAGAAAATAGAAAATTAAAAAAAACATTGGAT AGCTTTAAAAATCTGACCTTTCAGTTAGAATCCCTAGAAAAAGAGAATTCCCAACTTGAT GAGGAAAACTTAGAACTGCGAAGGAATGTAGAATCTTTGAAGTGTGCAAGCATGAAAATG GCTCAGCTACAGCTAGAAAACAAAGAACTGGAAAGTGAAAAAGAGCAACTTAAGAAGGGT TTGGAGCTCCTGAAAGCATCTTTCAAGAAAACAGAACGCTTAGAAGTTAGCTACCAGGGT TTAGATATAGAAAATCAAAGACTGCAAAAAACTTTAGAGAACAGCAATAAAAAAATCCAG CAATTAGAGAGTGAACTACAAGACTTAGAGATGGAAAATCAAACATTGCAGAAAAACCTA GAAGAACTAAAAATATCTAGCAAAAGACTAGAACAGCTGGAAAAAGAAAATAAATCATTA GAGCAAGAGACTTCTCAACTGGAAAAGGATAAGAAACAATTGGAGAAGGAAAATAAGAGA CTCCGACAACAAGCAGAAATTAAAGATACCACATTAGAAGAAAATAATGTGAAGATTGGA AATTTGGAAAAAGAAAACAAAACCCTATCCAAAGAAATTGGTATATATAAAGAATCTTGT GTCCGTCTGAAAGAACTAGAAAAAGAAAATAAGGAGCTTGTGAAAAGAGCAACTATTGAT ATAAAAACGTTGGTTACACTACGTGAGGATTTGGTGAGTGAAAAGTTGAAGACCCAACAG ATGAACAATGATCTCGAAAAATTAACTCATGAGCTTGAGAAGATAGGGTTAAATAAGGAG CGACTCTTACATGATGAACAAAGTACTGATGACAGGTATAAACTTTTGGAATCAAAATTA GAATCCACTCTTAAGAAGTCTCTTGAAATAAAAGAAGAAAAAATTGCTGCTTTAGAAGCT CGATTAGAAGAATCCACGAATTATAACCAGCAATTGCGCCAAGAACTTAAAACAGTGAAA AAAAATTATGAAGCTCTCAAACAGAGACAAGATGAGGAAAGGATGGTACAGAGCTCTCCT CCAATATCTGGTGAAGACAACAAATGGGAGCGAGAAAGTCAAGAAACGACTAGAGAACTT CTGAAAGTTAAAGACAGATTAATTGAAGTAGAAAGAAATAATGCTACACTGCAAGCAGAG AAGCAAGCGTTGAAAACTCAACTGAAGCAACTTGAGACACAGAACAATAATTTGCAGGCT CAGATTCTTGCACTTCAGAGGCAGACAGTGTCATTACAAGAACAGAATACCACTCTTCAA ACACAGAATGCCAAGCTTCAGGTTGAAAATTCCACCCTTAATTCCCAAAGTACCTCACTC ATGAACCAGAATGCCCAACTCCTAATCCAGCAGTCTTCCTTAGAAAATGAAAATGAATCT GTAATCAAAGAGCGAGAAGACCTAAAATCTCTCTATGATTCTCTGATCAAAGATCATGAA AAGCTGGAACTTCTTCATGAACGTCAGGCTTCAGAGTATGAATCTCTTATCTCTAAACAT GGAACTCTGAAGTCTGCCCACAAAAATCTTGAGGTGGAACATAGAGACCTTGAAGACCGT TACAATCAGTTATTAAAACAGAAAGGACAGTTGGAAGATTTGGAAAAAATGCTCAAAGTA GAACAGGAAAAAATGCTGCTTGAAAATAAAAATCATGAAACAGTAGCTGCAGAATACAAG AAACTTTGTGGTGAAAATGATAGGCTGAATCATACCTATAGTCAACTTTTAAAAGAGACT GAAGTTTTACAAACTGACCATAAAAATTTGAAAAGTCTTCTGAATAATTCCAAACTGGAA CAAACAAGATTAGAAGCTGAATTTTCAAAACTAAAGGAACAATACCAACAATTGGATATT ACATCAACCAAGCTGAATAACCAGTGTGAGTTGCTAAGCCAACTTAAAGGAAATTTAGAA GAAGAAAATCGGCATCTACTAGATCAAATTCAGACATTAATGCTACAGAACAGAACACTT TTGGAGCAGAATATGGAAAGCAAGGATCTTTTTCATGTTGAACAAAGACAGTACATTGAT AAGTTAAATGAATTAAGACGTCAGAAGGAGAAACTAGAAGAGAAAATTATGGATCAATAC AAATTTTATGACCCATCTCCTCCTAGAAGGAGAGGCAACTGGATTACTCTAAAAATGAGA AAATTGATAAAGTCTAAGAAAGATATTAATCGGGAACGCCAGAAATCTCTAACATTAACA CCCACCCGCTCAGACTCCAGTGAAGGATTTCTTCAGCTCCCTCATCAAGACAGTCAAGAT AGTTCTTCAGTAGGTTCAAACTCTTTAGAAGATGGCCAGACCTTGGGGACCAAGAAAAGC AGCATGGTTGCACTGAAAAGACTGCCCTTTTTGAGGAACAGACCGAAGGATAAAGACAAA ATGAAGGCCTGCTACCGTCGTTCCATGTCCATGAATGACCTGGTGCAGTCCATGGTCCTA GCAGGACAGTGGACAGGTAGTACTGAGAATTTGGAGGTTCCTGATGATATTTCAACGGGT AAAAGGAGAAAAGAATTGGGAGCTATGGCCTTCTCTACTACAGCCATCAACTTTTCAACT GTCAACTCTTCTGCAGGCTTCAGATCCAAGCAGTTGGTTAATAATAAAGATACTACATCC TTTGAAGACATAAGTCCACAAGGTGTTAGTGATGATTCTAGTACGGGATCAAGAGTTCAT GCTTCAAGACCAGCCAGCCTTGATAGTGGCAGAACATCCACTAGCAATAGCAATAATAAT GCTTCACTACATGAAGTCAAAGCAGGTGCAGTTAATAACCAAAGCAGGCCACAAAGCCAC AGCAGTGGAGAATTTAGCCTGCTTCATGACCATGAGGCTTGGTCCAGCAGTGGTAGCAGT CCAATCCAGTACTTGAAAAGACAGACCAGATCAAGCCCAGTGCTCCAGCACAAAATATCT GAAACACTGGAGAGTCGACATCACAAGATCAAAACTGGTTCCCCTGGAAGTGAAGTTGTT ACTCTACAACAGTTTTTGGAAGAAAGCAATAAGCTTACCTCAGTACAGATAAAGTCCTCA AGTCAAGAGAATCTTTTAGATGAAGTAATGAAAAGTTTGTCTGTCTCTTCTGACTTTTTG GGAAAAGACAAACCAGTTAGCTGTGGTCTGGCCAGGTCAGTAAGTGGAAAAACCCCAGGG GACTTCTATGATAGACGGACAACTAAGCCTGAGTTTTTGAGACCTGGTCCTCGAAAAACT GAAGATACCTACTTCATTAGTTCTGCGGGAAAACCTACACCAGGCACTCAAGGAAAAATA AAATTAGTAAAAGAATCTTCTCTGTCACGACAATCAAAAGATAGTAACCCTTATGCAACT TTACCTCGTGCAAGCAGCGTGATCTCAACTGCCGAAGGAACTACACGAAGGACAAGCATC CATGATTTTTTGACCAAGGACAGTAGACTGCCTATATCAGTTGATTCACCACCAGCTGCT GCTGACAGCAACACCACTGCAGCATCTAATGTGGACAAAGTACAAGAAAGCAGAAATTCA AAAAGCAGGTCTAGGGAGCAACAAAGCTCC |
| Restriction Sites | Please inquire |
| ACCN | NM_001135597 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001135597.1, NP_001129069.1 |
| RefSeq Size | 9827 bp |
| RefSeq ORF | 5613 bp |
| Locus ID | 55704 |
| UniProt ID | Q3V6T2 |
| Gene Summary | This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] Transcript Variant: This variant (1) encodes isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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