BRD2 (NM_001199455) Human Untagged Clone
CAT#: SC331314
BRD2 (untagged) - Homo sapiens bromodomain containing 2 (BRD2), transcript variant 3
CNY 7,980.00
货期*
5周
规格
Product images
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经常一起买 (4)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | BRD2-IT1; D6S113E; FSH; FSRG1; NAT; O27.1.1; RING3; RNF3 |
Vector | pCMV6-Entry |
Sequence Data |
>SC331314 representing NM_001199455.
Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGCTGCAAAACGTGACTCCCCACAATAAGCTCCCTGGGGAAGGGAATGCAGGGTTGCTGGGGCTGGGC CCAGAAGCAGCAGCACCAGGGAAGAGGATTCGAAAACCCTCTCTCTTGTATGAGGGCTTTGAGAGCCCC ACAATGGCTTCGGTGCCTGCTTTGCAACTTACCCCTGCCAACCCACCACCCCCGGAGGTGTCCAATCCC AAAAAGCCAGGACGAGTTACCAACCAGCTGCAATACCTACACAAGGTAGTGATGAAGGCTCTGTGGAAA CATCAGTTCGCATGGCCATTCCGGCAGCCTGTGGATGCTGTCAAACTGGGTCTACCGGATTATCACAAA ATTATAAAACAGCCTATGGACATGGGTACTATTAAGAGGAGACTTGAAAACAATTATTATTGGGCTGCT TCAGAGTGTATGCAAGATTTTAATACCATGTTCACCAACTGTTACATTTACAACAAGCCCACTGATGAT ATTGTCCTAATGGCACAAACGCTGGAAAAGATATTCCTACAGAAGGTTGCATCAATGCCACAAGAAGAA CAAGAGCTGGTAGTGACCATCCCTAAGAACAGCCACAAGAAGGGGGCCAAGTTGGCAGCGCTCCAGGGC AGTGTTACCAGTGCCCATCAGGTGCCTGCCGTCTCTTCTGTGTCACACACAGCCCTGTATACTCCTCCA CCTGAGATACCTACCACTGTCCTCAACATTCCCCACCCATCAGTCATTTCCTCTCCACTTCTCAAGTCC TTGCACTCTGCTGGACCCCCGCTCCTTGCTGTTACTGCAGCTCCTCCAGCCCAGCCCCTTGCCAAGAAA AAAGGCGTAAAGCGGAAAGCAGATACTACCACCCCTACACCTACAGCCATCTTGGCTCCTGGTTCTCCA GCTAGCCCTCCTGGGAGTCTTGAGCCTAAGGCAGCACGGCTTCCCCCTATGCGTAGAGAGAGTGGTCGC CCCATCAAGCCCCCACGCAAAGACTTGCCTGACTCTCAGCAACAACACCAGAGCTCTAAGAAAGGAAAG CTTTCAGAACAGTTAAAACATTGCAATGGCATTTTGAAGGAGTTACTCTCTAAGAAGCATGCTGCCTAT GCTTGGCCTTTCTATAAACCAGTGGATGCTTCTGCACTTGGCCTGCATGACTACCATGACATCATTAAG CACCCCATGGACCTCAGCACTGTCAAGCGGAAGATGGAGAACCGTGATTACCGGGATGCACAGGAGTTT GCTGCTGATGTACGGCTTATGTTCTCCAACTGCTATAAGTACAATCCCCCAGATCACGATGTTGTGGCA ATGGCACGAAAGCTACAGGATGTATTTGAGTTCCGTTATGCCAAGATGCCAGATGAACCACTAGAACCA GGGCCTTTACCAGTCTCTACTGCCATGCCCCCTGGCTTGGCCAAATCGTCTTCAGAGTCCTCCAGTGAG GAAAGTAGCAGTGAGAGCTCCTCTGAGGAAGAGGAGGAGGAAGATGAGGAGGACGAGGAGGAAGAAGAG AGTGAAAGCTCAGACTCAGAGGAAGAAAGGGCTCATCGCTTAGCAGAACTACAGGAACAGCTTCGGGCA GTACATGAACAACTGGCTGCTCTGTCCCAGGGTCCAATATCCAAGCCCAAGAGGAAAAGAGAGAAAAAA GAGAAAAAGAAGAAACGGAAGGCAGAGAAGCATCGAGGCCGAGCTGGGGCCGATGAAGATGACAAGGGG CCTAGGGCACCCCGCCCACCTCAACCTAAGAAGTCCAAGAAAGCAAGTGGCAGTGGGGGTGGCAGTGCT GCTTTAGGCCCTTCTGGCTTTGGACCTTCTGGAGGAAGTGGCACCAAACTCCAGGCTGGAGTGCAGTGG CGTGATCTCGGCTTACTGCAACCTCCACTTCTCGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCAAGT AGCCAGGATTACAGGCTCCCCAAAAAGGCCACAAAGACAGCCCCACCTGCCCTGCCTACAGGTTATGAT TCAGAGGAGGAGGAAGAGAGCAGGCCCATGAGTTACGATGAGAAGCGGCAGCTGAGCCTGGACATCAAC AAATTACCTGGGGAGAAGCTGGGCCGAGTTGTGCATATAATCCAAGCCAGGGAGCCCTCTTTACGTGAT TCAAACCCAGAAGAGATTGAGATTGATTTTGAAACACTCAAGCCATCCACACTTAGAGAGCTTGAGCGC TATGTCCTTTCCTGCCTACGTAAGAAACCCCGGAAGCCCTACACCATTAAGAAGCCTGTGGGAAAGACA AAGGAGGAACTGGCTTTGGAGAAAAAGCGGGAATTAGAAAAGCGGTTACAAGATGTCAGCGGACAGCTC AATTCTACTAAAAAGCCCCCCAAGAAAGCGAATGAGAAAACAGAGTCATCCTCTGCACAGCAAGTAGCA GTGTCACGCCTTAGCGCTTCCAGCTCCAGCTCAGATTCCAGCTCCTCCTCTTCCTCGTCGTCGTCTTCA GACACCAGTGATTCAGACTCAGGCTAA |
Restriction Sites | SgfI-MluI |
ACCN | NM_001199455 |
Insert Size | 2511 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001199455.1 |
RefSeq Size | 4602 bp |
RefSeq ORF | 2511 bp |
Locus ID | 6046 |
UniProt ID | P25440 |
Protein Families | Protein Kinase |
MW | 92 kDa |
Gene Summary | This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010] Transcript Variant: This variant (3) has an additional in-frame exon in the CDS compared to variant 1. The resulting isoform (2) is longer than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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