DEDD2 (NM_001270615) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	FLAME-3; FLAME3
Vector	pCMV6-Entry
Sequence Data	Fully Sequenced ORF (showhide) >SC332985 representing NM_001270615. Blue=Insert sequence Red=Cloning site Green=Tag(s) ATGGCGCTATCCGGGTCGACCCCGGCCCCGTGCTGGGAGGAGGATGAGTGCCTGGACTACTACGGGATG CTGTCGCTTCACCGTATGTTCGAGGTGGTGGGCGGGCAACTGACCGAGTGCGAGCTGGAGCTCCTGGCC TTTCTGCTGGATGAGGCTCCTGGCGCCGCCGGAGGCTTAGCCCGGGCCCGCAGCGGCCTAGAGCTCCTG CTGGAGCTGGAGCGCCGCGGGCAGTGCGACGAGAGCAACCTGCGGCTGCTGGGGCAACTCCTGCGCGTG CTGGCCCGCCACGACCTGCTGCCGCACCTGGCGCGCAAGCGGCGCCGGCCAGTGTCTCCAGAACGCTAT AGCTATGGCACCTCCAGCTCTTCAAAGAGGACAGAGGGTAGCTGCCGTCGCCGTCGGCAGTCAAGCAGT TCTGCAAATTCTCAGCAGGGCTCCCCCCCAACCAAGCGGCAGCGGCGGAGTCGGGGCCGGCCCAGTGGT GGTGCCAGACGGCGGCGGAGAGGGGCCCCAGCCGCACCCCAGCAGCAGTCAGAGCCCGCCAGACCTTCC TCTGAAGGCAAAGTGACCTGTGACATCCGGCTCCGGGTTCGAGCAGAGTACTGCGAGCATGGGCCAGCC TTGGAGCAGGGCGTGGCATCCCGGCGGCCCCAGGCGCTGGCGCGGCAGCTGGACGTGTTTGGGCAGGCC ACCGCAGTGCTGCGCTCAAGGGACCTGGGCTCTGTGGTTTGTGACATCAAGTTCTCAGAGCTCTCCTAT CTGGACGCCTTCTGGGGCGACTACCTGAGTGGCGCCCTGCTGCAGGCCCTGCGGGGCGTGTTCCTGACT GAGGCCCTGCGAGAGGCTGTGGGCCGGGAGGCTGTTCGCCTGCTGGTCAGTGTGGATGAGGCTGACTAT GAGGCTGGCCGGCGCCGCCTGTTGCTGATGGAGGAGGAAGGGGGGCGGCGCCCGACAGAGGCCTCCTGA
Restriction Sites	SgfI-MluI
ACCN	NM_001270615
Insert Size	966 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001270615.1
RefSeq Size	2010 bp
RefSeq ORF	966 bp
Locus ID	162989
UniProt ID	Q8WXF8
Protein Families	Druggable Genome, Transcription Factors
MW	35.6 kDa
Gene Summary	This gene encodes a nuclear-localized protein containing a death effector domain (DED). The encoded protein may regulate the trafficking of caspases and other proteins into the nucleus during death receptor-induced apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012] Transcript Variant: This variant (3) uses an alternate in-frame splice site in the coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.

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