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Cflar (BC023121) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR200009L4V
- LentiORF®
-
Lenti ORF particles, Cflar (GFP-tagged) - Mouse CASP8 and FADD-like apoptosis regulator (cDNA clone MGC:28609 IMAGE:4218551), 200ul, >10^7 TU/mL
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CNY 7,505.00
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Specifications
| Product Data | |
| Product Name | Cflar (BC023121) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | MRIT, CLARP, FLAME, Casper, I-FLICE, Flip |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | BC023121 |
| ORF Size | 120 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR200009).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | BC023121 |
| RefSeq Size | 2019 bp |
| RefSeq ORF | 122 bp |
| Locus ID | 12633 |
| Gene Summary | Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity (By similarity).[UniProtKB/Swiss-Prot Function] |
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