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Bnip3 (NM_009760) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR201757L4V
- LentiORF®
-
Lenti ORF particles, Bnip3 (GFP-tagged) - Mouse BCL2/adenovirus E1B interacting protein 3 (Bnip3), nuclear gene encoding mitochondrial protein, 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
| Product Data | |
| Product Name | Bnip3 (NM_009760) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | Nip3 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_009760 |
| ORF Size | 564 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR201757).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_009760.4, NP_033890.1 |
| RefSeq Size | 1756 bp |
| RefSeq ORF | 564 bp |
| Locus ID | 12176 |
| Gene Summary | Apoptosis-inducing protein that can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2 (By similarity). Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane may play a critical role in the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix (By similarity). The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix (By similarity). Plays an important role in the calprotectin (S100A8/A9)-induced cell death pathway (By similarity).[UniProtKB/Swiss-Prot Function] |
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