Arhgdia (NM_133796) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR202112L4V

  • LentiORF®

Lenti ORF particles, Arhgdia (GFP-tagged) - Mouse Rho GDP dissociation inhibitor (GDI) alpha (Arhgdia), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 8,360.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Arhgdia (NM_133796) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms 5330430M07Rik; Gdi-1; Rho-GDI; RhoDGI; RhoGDI-1
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_133796
ORF Size 615 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR202112).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_133796.5
RefSeq Size 2732 bp
RefSeq ORF 615 bp
Locus ID 192662
Gene Summary Controls Rho proteins homeostasis. Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Retains Rho proteins such as CDC42, RAC1 and RHOA in an inactive cytosolic pool, regulating their stability and protecting them from degradation. Actively involved in the recycling and distribution of activated Rho GTPases in the cell, mediates extraction from membranes of both inactive and activated molecules due its exceptionally high affinity for prenylated forms. Through the modulation of Rho proteins, may play a role in cell motility regulation. In glioma cells, inhibits cell migration and invasion by mediating the signals of SEMA5A and PLXNB3 that lead to inactivation of RAC1.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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