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Dnajb9 (NM_013760) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR202557L3V
- LentiORF®
-
Lenti ORF particles, Dnajb9 (Myc-DDK-tagged) - Mouse DnaJ (Hsp40) homolog, subfamily B, member 9 (Dnajb9), 200ul, >10^7 TU/mL
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CNY 7,410.00
货期*
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规格
| Cited in 1 publication. |
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经常一起买 (2)
Specifications
| Product Data | |
| Product Name | Dnajb9 (NM_013760) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | AA408011; AA673251; AA673481; AW556981; ERdj4; Mdg1; mDj7 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_013760 |
| ORF Size | 669 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR202557).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_013760.3, NP_038788.2 |
| RefSeq Size | 1865 bp |
| RefSeq ORF | 669 bp |
| Locus ID | 27362 |
| Gene Summary | Co-chaperone for Hsp70 protein HSPA5/BiP that acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR) (By similarity). J domain-containing co-chaperones stimulate the ATPase activity of Hsp70 proteins and are required for efficient substrate recognition by Hsp70 proteins (PubMed:11836248). In the unstressed endoplasmic reticulum, interacts with the luminal region of ERN1/IRE1 and selectively recruits HSPA5/BiP: HSPA5/BiP disrupts the dimerization of the active ERN1/IRE1 luminal region, thereby inactivating ERN1/IRE1 (By similarity). Also involved in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins (PubMed:22267725). Required for survival of B-cell progenitors and normal antibody production (PubMed:25222125).[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Hepatic DNAJB9 Drives Anabolic Biasing to Reduce Steatosis and Obesity.
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Cell reports
,PubMed ID 32049014
[Dnajb9]
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