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Chac1 (NM_026929) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR202572L4V
- LentiORF®
-
Lenti ORF particles, Chac1 (GFP-tagged) - Mouse ChaC, cation transport regulator-like 1 (E. coli) (Chac1), 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
| Product Data | |
| Product Name | Chac1 (NM_026929) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 1810008K03Rik |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_026929 |
| ORF Size | 672 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR202572).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_026929.2, NP_081205.1 |
| RefSeq Size | 1583 bp |
| RefSeq ORF | 672 bp |
| Locus ID | 69065 |
| Gene Summary | Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides. Glutathione depletion is an important factor for apoptosis initiation and execution. Acts as a pro-apoptotic component of the unfolded protein response pathway by mediating the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade (By similarity). Negative regulator of Notch signaling pathway involved in embryonic neurogenesis: acts by inhibiting Notch cleavage by furin, maintaining Notch in an immature inactive form, thereby promoting neurogenesis in embryos (PubMed:22445366).[UniProtKB/Swiss-Prot Function] |
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