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Rad51l1 (BC058184) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR203142L3V
- LentiORF®
-
Lenti ORF particles, Rad51l1 (Myc-DDK-tagged) - Mouse RAD51-like 1 (S. cerevisiae) (cDNA clone MGC:67754 IMAGE:5322190), 200ul, >10^7 TU/mL
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CNY 9,975.00
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Specifications
| Product Data | |
| Product Name | Rad51l1 (BC058184) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | R51H2, mREC2 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | BC058184 |
| ORF Size | 744 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR203142).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | BC058184.1 |
| RefSeq Size | 1315 bp |
| RefSeq ORF | 746 bp |
| Locus ID | 19363 |
| Gene Summary | Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. May promote the assembly of presynaptic RAD51 nucleoprotein filaments. Binds single-stranded DNA and double-stranded DNA and has DNA-dependent ATPase activity. Part of the RAD21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. The BCDX2 subcomplex RAD51B:RAD51C exhibits single-stranded DNA-dependent ATPase activity suggesting an involvement in early stages of the HR pathway (By similarity).[UniProtKB/Swiss-Prot Function] |
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