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Ptpmt1 (NM_025576) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR203396L3V
- LentiORF®
-
Lenti ORF particles, Ptpmt1 (Myc-DDK-tagged) - Mouse protein tyrosine phosphatase, mitochondrial 1 (Ptpmt1), nuclear gene encoding mitochondrial protein, 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | Ptpmt1 (NM_025576) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 1110001D10Rik; 2810004N20Rik; PLIP |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_025576 |
| ORF Size | 783 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR203396).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_025576.2, NP_079852.1 |
| RefSeq Size | 1322 bp |
| RefSeq ORF | 786 bp |
| Locus ID | 66461 |
| Gene Summary | Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) (PubMed:21641550, PubMed:21730175). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle (PubMed:21641550). Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production (By similarity). Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues (By similarity). Probably involved in regulation of insulin secretion in pancreatic beta cells (By similarity). May prevent intrinsic apoptosis, probably by regulating mitochondrial membrane integrity (By similarity).[UniProtKB/Swiss-Prot Function] |
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