Setd4 (BC029101) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR203574L4V
- LentiORF®
Lenti ORF particles, Setd4 (GFP-tagged) - Mouse SET domain containing 4 (cDNA clone MGC:27899 IMAGE:3499483), 200ul, >10^7 TU/mL
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CNY 11,115.00
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Specifications
Product Data | |
Product Name | Setd4 (BC029101) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | AY037804; C21orf18; ORF21 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | BC029101 |
ORF Size | 807 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR203574).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | BC029101 |
RefSeq Size | 2360 bp |
RefSeq ORF | 809 bp |
Locus ID | 224440 |
Gene Summary | Histone-lysine N-methyltransferase that acts as a regulator of cell proliferation, cell differentiation and inflammatory response (PubMed:31376731, PubMed:31794893, PubMed:33506343). Regulates the inflammatory response by mediating mono- and dimethylation of 'Lys-4' of histone H3 (H3K4me1 and H3K4me2, respectively), leading to activate the transcription of proinflammatory cytokines IL6 and TNF-alpha (PubMed:31376731). Also involved in the regulation of stem cell quiescence by catalyzing the trimethylation of 'Lys-20' of histone H4 (H4K20me3), thereby promoting heterochromatin formation (By similarity). Involved in proliferation, migration, paracrine and myogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) (PubMed:33506343).[UniProtKB/Swiss-Prot Function] |
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