Smug1 (NM_027885) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR203761L3V
- LentiORF®
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Lenti ORF particles, Smug1 (Myc-DDK-tagged) - Mouse single-strand selective monofunctional uracil DNA glycosylase (Smug1), 200ul, >10^7 TU/mL
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CNY 7,410.00
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规格
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Specifications
Product Data | |
Product Name | Smug1 (NM_027885) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | 1200013B09Rik; A930006H09Rik; C85220 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_027885 |
ORF Size | 840 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR203761).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_027885.3, NP_082161.2 |
RefSeq Size | 3611 bp |
RefSeq ORF | 840 bp |
Locus ID | 71726 |
Gene Summary | Recognizes base lesions in the genome and initiates base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA with a preference for single-stranded DNA substrates. The activity is greater toward mismatches (U/G) compared to matches (U/A). Excises uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5-hydroxymethyluracil (hmU)] in ssDNA and dsDNA, but not analogous cytosine derivatives (5-hydroxycytosine and 5-formylcytosine), nor other oxidized bases. The activity is damage-specific and salt-dependent. The substrate preference is the following: ssDNA > dsDNA (G pair) = dsDNA (A pair) at low salt concentration, and dsDNA (G pair) > dsDNA (A pair) > ssDNA at high salt concentration.[UniProtKB/Swiss-Prot Function] |
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