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Il1r2 (BC032962) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR203789L3V
- LentiORF®
-
Lenti ORF particles, Il1r2 (Myc-DDK-tagged) - Mouse interleukin 1 receptor, type II (cDNA clone MGC:41170 IMAGE:1282531), 200ul, >10^7 TU/mL
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CNY 9,975.00
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Specifications
| Product Data | |
| Product Name | Il1r2 (BC032962) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | CD121b; Il1r-2 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | BC032962 |
| ORF Size | 840 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR203789).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | BC032962, AAH32962 |
| RefSeq Size | 1096 bp |
| RefSeq ORF | 842 bp |
| Locus ID | 16178 |
| Gene Summary | Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors (By similarity).[UniProtKB/Swiss-Prot Function] |
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