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Mafb (NM_010658) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR204681L4V
- LentiORF®
-
Lenti ORF particles, Mafb (GFP-tagged) - Mouse v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) (Mafb), 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
| Product Data | |
| Product Name | Mafb (NM_010658) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | kr; Kreisler; Krml; Krml1 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_010658 |
| ORF Size | 969 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR204681).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_010658.3, NP_034788.1 |
| RefSeq Size | 3389 bp |
| RefSeq ORF | 972 bp |
| Locus ID | 16658 |
| Gene Summary | Acts as a transcriptional activator or repressor. Plays a pivotal role in regulating lineage-specific hematopoiesis by repressing ETS1-mediated transcription of erythroid-specific genes in myeloid cells. Required for monocytic, macrophage, osteoclast, podocyte and islet beta cell differentiation. Involved in renal tubule survival and F4/80 maturation. Activates the insulin and glucagon promoters. Together with PAX6, transactivates weakly the glucagon gene promoter through the G1 element. SUMO modification controls its transcriptional activity and ability to specify macrophage fate. Binds element G1 on the glucagon promoter. Involved either as an oncogene or as a tumor suppressor, depending on the cell context.[UniProtKB/Swiss-Prot Function] |
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