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Wdr77 (NM_027432) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR205136L3V
- LentiORF®
-
Lenti ORF particles, Wdr77 (Myc-DDK-tagged) - Mouse WD repeat domain 77 (Wdr77), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
| Product Data | |
| Product Name | Wdr77 (NM_027432) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 2610003I18Rik; 2610312E17Rik; C79984; p44/MEP50 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_027432 |
| ORF Size | 1029 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR205136).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_027432.3, NP_081708.1 |
| RefSeq Size | 3553 bp |
| RefSeq ORF | 1029 bp |
| Locus ID | 70465 |
| Gene Summary | Non-catalytic component of the methylosome complex, composed of PRMT5, WDR77 and CLNS1A, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The methylosome complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage (PubMed:19584108).[UniProtKB/Swiss-Prot Function] |
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