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Ppp4r2 (BC056340) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR206596L4V
- LentiORF®
-
Lenti ORF particles, Ppp4r2 (GFP-tagged) - Mouse protein phosphatase 4, regulatory subunit 2 (cDNA clone MGC:73463 IMAGE:5703151), 200ul, >10^7 TU/mL
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CNY 11,115.00
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Specifications
| Product Data | |
| Product Name | Ppp4r2 (BC056340) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | BE691708; C230060M08Rik |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | BC056340 |
| ORF Size | 1251 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR206596).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | BC056340, AAH56340 |
| RefSeq Size | 2769 bp |
| RefSeq ORF | 1253 bp |
| Locus ID | 232314 |
| Gene Summary | Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair (By similarity). Mediates RPA2 dephosphorylation by recruiting PPP4C to RPA2 in a DNA damage-dependent manner. RPA2 dephosphorylation is required for the efficient RPA2-mediated recruitment of RAD51 to chromatin following double strand breaks, an essential step for DNA repair (By similarity).[UniProtKB/Swiss-Prot Function] |
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