Abhd2 (NM_018811) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR206769L4V
- LentiORF®
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Lenti ORF particles, Abhd2 (GFP-tagged) - Mouse abhydrolase domain containing 2 (Abhd2), 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
Product Data | |
Product Name | Abhd2 (NM_018811) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | 2210009N18Rik; Labh-2; LABH2 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_018811 |
ORF Size | 1278 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR206769).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_018811.4 |
RefSeq Size | 2903 bp |
RefSeq ORF | 1278 bp |
Locus ID | 54608 |
Gene Summary | Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol (AG) from cell membrane. Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol (1AG) and 2-arachidonoylglycerol (2AG) to glycerol and arachidonic acid (AA). Also displays an ester hydrolase activity against acetyl ester, butanoate ester and hexadecanoate ester. Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2AG, an inhibitor of the sperm calcium channel CatSper, leading to calcium influx via CatSper and sperm activation (By similarity). Involved in acrosomal reaction (Probable). May also play a role in smooth muscle cells migration (PubMed:15721306).[UniProtKB/Swiss-Prot Function] |
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